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Items: 1 to 20 of 41

1.

Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites.

Kimura T, Tsutsumi K, Taoka M, Saito T, Masuda-Suzukake M, Ishiguro K, Plattner F, Uchida T, Isobe T, Hasegawa M, Hisanaga S.

J Biol Chem. 2013 Mar 15;288(11):7968-77. doi: 10.1074/jbc.M112.433326. Epub 2013 Jan 28.

2.

Pinning down phosphorylated tau and tauopathies.

Lim J, Lu KP.

Biochim Biophys Acta. 2005 Jan 3;1739(2-3):311-22. Epub 2004 Nov 30. Review.

3.

Pin1: a new outlook in Alzheimer's disease.

Lonati E, Masserini M, Bulbarelli A.

Curr Alzheimer Res. 2011 Sep;8(6):615-22. Review.

PMID:
21605045
4.

Physiological and pathological phosphorylation of tau by Cdk5.

Kimura T, Ishiguro K, Hisanaga S.

Front Mol Neurosci. 2014 Jul 15;7:65. doi: 10.3389/fnmol.2014.00065. eCollection 2014. Review.

5.

Phosphorylation-dependent prolyl isomerization: a novel signaling regulatory mechanism.

Zhou XZ, Lu PJ, Wulf G, Lu KP.

Cell Mol Life Sci. 1999 Nov 30;56(9-10):788-806. Review.

PMID:
11212339
6.

Tau pathology in Alzheimer disease and other tauopathies.

Iqbal K, Alonso Adel C, Chen S, Chohan MO, El-Akkad E, Gong CX, Khatoon S, Li B, Liu F, Rahman A, Tanimukai H, Grundke-Iqbal I.

Biochim Biophys Acta. 2005 Jan 3;1739(2-3):198-210. Review.

7.

Current advances on different kinases involved in tau phosphorylation, and implications in Alzheimer's disease and tauopathies.

Ferrer I, Gomez-Isla T, Puig B, Freixes M, Ribé E, Dalfó E, Avila J.

Curr Alzheimer Res. 2005 Jan;2(1):3-18. Review.

PMID:
15977985
8.

Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease.

Salminen A, Ojala J, Kaarniranta K, Hiltunen M, Soininen H.

Prog Neurobiol. 2011 Jan;93(1):99-110. doi: 10.1016/j.pneurobio.2010.10.006. Epub 2010 Nov 5. Review.

PMID:
21056617
9.

Tauopathies and tau oligomers.

Takashima A.

J Alzheimers Dis. 2013;37(3):565-8. doi: 10.3233/JAD-130653. Review.

PMID:
23948895
10.

Mechanisms of tau-induced neurodegeneration.

Iqbal K, Liu F, Gong CX, Alonso Adel C, Grundke-Iqbal I.

Acta Neuropathol. 2009 Jul;118(1):53-69. doi: 10.1007/s00401-009-0486-3. Epub 2009 Jan 30. Review.

11.

Phosphorylation-specific peptidyl-prolyl isomerization of neuronal cytoskeletal proteins by Pin1: implications for therapeutics in neurodegeneration.

Rudrabhatla P, Pant HC.

J Alzheimers Dis. 2010;19(2):389-403. doi: 10.3233/JAD-2010-1243. Review.

PMID:
20110589
12.

Significance and mechanism of Alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion.

Iqbal K, Alonso Adel C, El-Akkad E, Gong CX, Haque N, Khatoon S, Pei JJ, Tsujio I, Wang JZ, Grundke-Iqbal I.

J Mol Neurosci. 2002 Aug-Oct;19(1-2):95-9. Review.

PMID:
12212801
13.

Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration.

Wang JZ, Xia YY, Grundke-Iqbal I, Iqbal K.

J Alzheimers Dis. 2013;33 Suppl 1:S123-39. Review.

PMID:
22710920
14.

Mechanism of neurofibrillary degeneration and pharmacologic therapeutic approach.

Iqbal K, Alonso AD, Gondal JA, Gong CX, Haque N, Khatoon S, Sengupta A, Wang JZ, Grundke-Iqbal I.

J Neural Transm Suppl. 2000;59:213-22. Review.

PMID:
10961432
15.

Pin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism?

Balastik M, Lim J, Pastorino L, Lu KP.

Biochim Biophys Acta. 2007 Apr;1772(4):422-9. Epub 2007 Jan 23. Review.

16.

[Unexpected roles of the peptidyl-prolyl cis/trans isomerase Pin1].

Lavoie SB, Albert AL, Vincent M.

Med Sci (Paris). 2003 Dec;19(12):1251-8. Review. French.

17.

Deregulated Cdk5 activity is involved in inducing Alzheimer's disease.

Shukla V, Skuntz S, Pant HC.

Arch Med Res. 2012 Nov;43(8):655-62. doi: 10.1016/j.arcmed.2012.10.015. Epub 2012 Nov 7. Review.

18.

Role of protein phosphatase 2A in Alzheimer's disease.

Rudrabhatla P, Pant HC.

Curr Alzheimer Res. 2011 Sep;8(6):623-32. Review.

PMID:
21605044
19.

Tau in Alzheimer disease and related tauopathies.

Iqbal K, Liu F, Gong CX, Grundke-Iqbal I.

Curr Alzheimer Res. 2010 Dec;7(8):656-64. Review.

20.

The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease.

Blair LJ, Baker JD, Sabbagh JJ, Dickey CA.

J Neurochem. 2015 Apr;133(1):1-13. doi: 10.1111/jnc.13033. Epub 2015 Feb 24. Review.

PMID:
25628064
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