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Results: 1 to 20 of 22

1.

Expedient synthesis of highly potent antagonists of inhibitor of apoptosis proteins (IAPs) with unique selectivity for ML-IAP.

Vamos M, Welsh K, Finlay D, Lee PS, Mace PD, Snipas SJ, Gonzalez ML, Ganji SR, Ardecky RJ, Riedl SJ, Salvesen GS, Vuori K, Reed JC, Cosford ND.

ACS Chem Biol. 2013 Apr 19;8(4):725-32. doi: 10.1021/cb3005512. Epub 2013 Feb 5.

PMID:
23323685
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Inhibitors of apoptosis proteins (IAPs) as potential molecular targets for therapy of hematological malignancies.

Smolewski P, Robak T.

Curr Mol Med. 2011 Nov;11(8):633-49. Review.

PMID:
21902653
[PubMed - indexed for MEDLINE]
3.

The inhibitors of apoptosis (IAPs) as cancer targets.

Hunter AM, LaCasse EC, Korneluk RG.

Apoptosis. 2007 Sep;12(9):1543-68. Review.

PMID:
17573556
[PubMed - indexed for MEDLINE]
4.

Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family.

Eckelman BP, Salvesen GS, Scott FL.

EMBO Rep. 2006 Oct;7(10):988-94. Review.

PMID:
17016456
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Inhibitors of apoptotic proteins: new targets for anticancer therapy.

Saleem M, Qadir MI, Perveen N, Ahmad B, Saleem U, Irshad T, Ahmad B.

Chem Biol Drug Des. 2013 Sep;82(3):243-51. doi: 10.1111/cbdd.12176. Review.

PMID:
23790005
[PubMed - indexed for MEDLINE]
6.

The inhibitors of apoptosis: there is more to life than Bcl2.

Liston P, Fong WG, Korneluk RG.

Oncogene. 2003 Nov 24;22(53):8568-80. Review.

PMID:
14634619
[PubMed - indexed for MEDLINE]
7.

IAPs: more than just inhibitors of apoptosis proteins.

Dubrez-Daloz L, Dupoux A, Cartier J.

Cell Cycle. 2008 Apr 15;7(8):1036-46. Epub 2008 Feb 11. Review.

PMID:
18414036
[PubMed - indexed for MEDLINE]
Free Article
8.

The inhibitors of apoptosis (IAPs) and their emerging role in cancer.

LaCasse EC, Baird S, Korneluk RG, MacKenzie AE.

Oncogene. 1998 Dec 24;17(25):3247-59. Review.

PMID:
9916987
[PubMed - indexed for MEDLINE]
Free Article
9.

Inhibitor of apoptosis proteins: fascinating biology leads to attractive tumor therapeutic targets.

Varfolomeev E, Vucic D.

Future Oncol. 2011 May;7(5):633-48. doi: 10.2217/fon.11.40. Review.

PMID:
21568679
[PubMed - indexed for MEDLINE]
10.

Targeting IAP proteins for therapeutic intervention in cancer.

Fulda S, Vucic D.

Nat Rev Drug Discov. 2012 Feb 1;11(2):109-24. doi: 10.1038/nrd3627. Review. Erratum in: Nat Rev Drug Discov. 2012 Apr;11(4):331.

PMID:
22293567
[PubMed - indexed for MEDLINE]
11.

Molecular pathways: targeting inhibitor of apoptosis proteins in cancer--from molecular mechanism to therapeutic application.

Fulda S.

Clin Cancer Res. 2014 Jan 15;20(2):289-95. doi: 10.1158/1078-0432.CCR-13-0227. Epub 2013 Nov 22. Review.

PMID:
24270683
[PubMed - indexed for MEDLINE]
12.

Targeting endogenous inhibitors of apoptosis for treatment of cancer, stroke and multiple sclerosis.

Holcík M.

Expert Opin Ther Targets. 2004 Jun;8(3):241-53. Review.

PMID:
15161430
[PubMed - indexed for MEDLINE]
13.

Modulation of immune signalling by inhibitors of apoptosis.

Beug ST, Cheung HH, LaCasse EC, Korneluk RG.

Trends Immunol. 2012 Nov;33(11):535-45. doi: 10.1016/j.it.2012.06.004. Epub 2012 Jul 24. Review.

PMID:
22836014
[PubMed - indexed for MEDLINE]
14.

IAP-targeted therapies for cancer.

LaCasse EC, Mahoney DJ, Cheung HH, Plenchette S, Baird S, Korneluk RG.

Oncogene. 2008 Oct 20;27(48):6252-75. doi: 10.1038/onc.2008.302. Review.

PMID:
18931692
[PubMed - indexed for MEDLINE]
15.

The inhibitor of apoptosis protein family and its antagonists in acute leukemias.

Wrzesień-Kuś A, Smolewski P, Sobczak-Pluta A, Wierzbowska A, Robak T.

Apoptosis. 2004 Nov;9(6):705-15. Review.

PMID:
15505413
[PubMed - indexed for MEDLINE]
16.

Inhibitor of apoptosis proteins (IAPs) as regulatory factors of hepatic apoptosis.

Wang K, Lin B.

Cell Signal. 2013 Oct;25(10):1970-80. doi: 10.1016/j.cellsig.2013.06.003. Epub 2013 Jun 11. Review.

PMID:
23770286
[PubMed - indexed for MEDLINE]
17.

[The role of the inhibitor of apoptosis protein (IAP) family in hematological malignancies].

Grzybowska-Izydorczyk O, Smolewski P.

Postepy Hig Med Dosw (Online). 2008 Feb 14;62:55-63. Review. Polish.

PMID:
18283236
[PubMed - indexed for MEDLINE]
Free Article
18.

Anti-cancer IAP antagonists promote bone metastasis: a cautionary tale.

Yang C, Novack DV.

J Bone Miner Metab. 2013 Sep;31(5):496-506. doi: 10.1007/s00774-013-0479-0. Epub 2013 Jun 6. Review.

PMID:
23740289
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function.

Wright CW, Duckett CS.

J Clin Invest. 2005 Oct;115(10):2673-8. Review.

PMID:
16200201
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Inhibitor of apoptosis proteins and apoptosis.

Wei Y, Fan T, Yu M.

Acta Biochim Biophys Sin (Shanghai). 2008 Apr;40(4):278-88. Review.

PMID:
18401525
[PubMed - indexed for MEDLINE]
Free Article
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