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Results: 17

1.

Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models.

Armakola M, Higgins MJ, Figley MD, Barmada SJ, Scarborough EA, Diaz Z, Fang X, Shorter J, Krogan NJ, Finkbeiner S, Farese RV Jr, Gitler AD.

Nat Genet. 2012 Dec;44(12):1302-9. doi: 10.1038/ng.2434. Epub 2012 Oct 28.

PMID:
23104007
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

TDP-43 toxicity in yeast.

Armakola M, Hart MP, Gitler AD.

Methods. 2011 Mar;53(3):238-45. doi: 10.1016/j.ymeth.2010.11.006. Epub 2010 Nov 27. Review.

PMID:
21115123
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis.

Wang DB, Gitcho MA, Kraemer BC, Klein RL.

Eur J Neurosci. 2011 Oct;34(8):1179-88. doi: 10.1111/j.1460-9568.2011.07803.x. Epub 2011 Jul 21. Review.

PMID:
21777407
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS.

Ito D, Suzuki N.

Neurology. 2011 Oct 25;77(17):1636-43. doi: 10.1212/WNL.0b013e3182343365. Epub 2011 Sep 28. Review.

PMID:
21956718
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

RNA-binding proteins with prion-like domains in ALS and FTLD-U.

Gitler AD, Shorter J.

Prion. 2011 Jul-Sep;5(3):179-87. doi: 10.4161/pri.5.3.17230. Epub 2011 Jul 1. Review.

PMID:
21847013
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis.

Pesiridis GS, Lee VM, Trojanowski JQ.

Hum Mol Genet. 2009 Oct 15;18(R2):R156-62. doi: 10.1093/hmg/ddp303. Review.

PMID:
19808791
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

[Molecular link between inefficient GluA2 RNA editing and TDP-43 pathology in ALS motor neurons].

Kwak S.

Brain Nerve. 2012 May;64(5):549-56. Review. Japanese.

PMID:
22570068
[PubMed - indexed for MEDLINE]
8.

How do the RNA-binding proteins TDP-43 and FUS relate to amyotrophic lateral sclerosis and frontotemporal degeneration, and to each other?

Baloh RH.

Curr Opin Neurol. 2012 Dec;25(6):701-7. doi: 10.1097/WCO.0b013e32835a269b. Review.

PMID:
23041957
[PubMed - indexed for MEDLINE]
9.

[The implications of TDP-43 mutations in pathogenesis of amyotrophic lateral sclerosis].

Ishihara T, Yokoseki A, Nishizawa M, Takahashi H, Onodera O.

Brain Nerve. 2009 Nov;61(11):1301-7. Review. Japanese.

PMID:
19938687
[PubMed - indexed for MEDLINE]
10.

Stress granules as crucibles of ALS pathogenesis.

Li YR, King OD, Shorter J, Gitler AD.

J Cell Biol. 2013 Apr 29;201(3):361-72. doi: 10.1083/jcb.201302044. Review.

PMID:
23629963
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: disease-associated pathways.

Barmada SJ, Finkbeiner S.

Rev Neurosci. 2010;21(4):251-72. Review.

PMID:
21086759
[PubMed - indexed for MEDLINE]
12.

TDP-43 and FUS/TLS: sending a complex message about messenger RNA in amyotrophic lateral sclerosis?

Strong MJ, Volkening K.

FEBS J. 2011 Oct;278(19):3569-77. doi: 10.1111/j.1742-4658.2011.08277.x. Epub 2011 Sep 6. Review.

PMID:
21810174
[PubMed - indexed for MEDLINE]
13.

[Implications of microRNA dysfunction in the pathogenesis of ALS].

Kawahara Y.

Rinsho Shinkeigaku. 2010 Nov;50(11):979-81. Review. Japanese.

PMID:
21921534
[PubMed - indexed for MEDLINE]
14.

[Clinical and pathological spectrum of TDP-43 associated ALS].

Onodera O, Yokoseki A, Tan CF, Ishihara T, Nishiira Y, Toyoshima Y, Kakita A, Nishizawa M, Takahashi H.

Rinsho Shinkeigaku. 2010 Nov;50(11):940-2. Review. Japanese.

PMID:
21921519
[PubMed - indexed for MEDLINE]
15.

Using yeast models to probe the molecular basis of amyotrophic lateral sclerosis.

Bastow EL, Gourlay CW, Tuite MF.

Biochem Soc Trans. 2011 Oct;39(5):1482-7. doi: 10.1042/BST0391482. Review.

PMID:
21936838
[PubMed - indexed for MEDLINE]
16.

SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments.

Joyce PI, Fratta P, Fisher EM, Acevedo-Arozena A.

Mamm Genome. 2011 Aug;22(7-8):420-48. doi: 10.1007/s00335-011-9339-1. Epub 2011 Jun 26. Review.

PMID:
21706386
[PubMed - indexed for MEDLINE]
17.

Does a loss of TDP-43 function cause neurodegeneration?

Xu ZS.

Mol Neurodegener. 2012 Jun 14;7:27. doi: 10.1186/1750-1326-7-27. Review.

PMID:
22697423
[PubMed - indexed for MEDLINE]
Free PMC Article
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