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Results: 14

1.

Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer.

Abkevich V, Timms KM, Hennessy BT, Potter J, Carey MS, Meyer LA, Smith-McCune K, Broaddus R, Lu KH, Chen J, Tran TV, Williams D, Iliev D, Jammulapati S, FitzGerald LM, Krivak T, DeLoia JA, Gutin A, Mills GB, Lanchbury JS.

Br J Cancer. 2012 Nov 6;107(10):1776-82. doi: 10.1038/bjc.2012.451. Epub 2012 Oct 9.

PMID:
23047548
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Therapeutic exploitation of tumor cell defects in homologous recombination.

Powell SN, Kachnic LA.

Anticancer Agents Med Chem. 2008 May;8(4):448-60. Review.

PMID:
18473729
[PubMed - indexed for MEDLINE]
3.

Minding the gap: the underground functions of BRCA1 and BRCA2 at stalled replication forks.

Nagaraju G, Scully R.

DNA Repair (Amst). 2007 Jul 1;6(7):1018-31. Epub 2007 Mar 26. Review.

PMID:
17379580
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Targeting the DNA repair defect of BRCA tumours.

Turner N, Tutt A, Ashworth A.

Curr Opin Pharmacol. 2005 Aug;5(4):388-93. Review.

PMID:
15955736
[PubMed - indexed for MEDLINE]
5.

Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers.

Vollebergh MA, Jonkers J, Linn SC.

Cell Mol Life Sci. 2012 Jan;69(2):223-45. doi: 10.1007/s00018-011-0809-0. Epub 2011 Sep 16. Review.

PMID:
21922196
[PubMed - indexed for MEDLINE]
6.

Homologous repair of DNA damage and tumorigenesis: the BRCA connection.

Jasin M.

Oncogene. 2002 Dec 16;21(58):8981-93. Review.

PMID:
12483514
[PubMed - indexed for MEDLINE]
Free Article
7.

Secondary BRCA1 and BRCA2 alterations and acquired chemoresistance.

Wang W, Figg WD.

Cancer Biol Ther. 2008 Jul;7(7):1004-5. Review.

PMID:
18720553
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The BRCA1/2 pathway prevents hematologic cancers in addition to breast and ovarian cancers.

Friedenson B.

BMC Cancer. 2007 Aug 6;7:152. Review.

PMID:
17683622
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

In brief: BRCA1 and BRCA2.

Foulkes WD, Shuen AY.

J Pathol. 2013 Aug;230(4):347-9. doi: 10.1002/path.4205. Review.

PMID:
23620175
[PubMed - indexed for MEDLINE]
10.

BRCA1 and BRCA2: different roles in a common pathway of genome protection.

Roy R, Chun J, Powell SN.

Nat Rev Cancer. 2011 Dec 23;12(1):68-78. doi: 10.1038/nrc3181. Review.

PMID:
22193408
[PubMed - indexed for MEDLINE]
11.

BRCA gene structure and function in tumor suppression: a repair-centric perspective.

Murphy CG, Moynahan ME.

Cancer J. 2010 Jan-Feb;16(1):39-47. doi: 10.1097/PPO.0b013e3181cf0204. Review.

PMID:
20164689
[PubMed - indexed for MEDLINE]
12.

PARP inhibitors and epithelial ovarian cancer: an approach to targeted chemotherapy and personalised medicine.

Mukhopadhyay A, Curtin N, Plummer R, Edmondson RJ.

BJOG. 2011 Mar;118(4):429-32. doi: 10.1111/j.1471-0528.2010.02838.x. Epub 2011 Jan 18. Review.

PMID:
21244617
[PubMed - indexed for MEDLINE]
13.

Role of BRCA gene dysfunction in breast and ovarian cancer predisposition.

Scully R.

Breast Cancer Res. 2000;2(5):324-30. Epub 2000 Jul 13. Review.

PMID:
11250724
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Hereditary breast and ovarian cancer: new genes, new treatments, new concepts.

Meindl A, Ditsch N, Kast K, Rhiem K, Schmutzler RK.

Dtsch Arztebl Int. 2011 May;108(19):323-30. doi: 10.3238/arztebl.2011.0323. Epub 2011 May 13. Review.

PMID:
21637635
[PubMed - indexed for MEDLINE]
Free PMC Article

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