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Items: 9

1.

Rational design of Rho GTPase-targeting inhibitors.

Shang X, Zheng Y.

Methods Mol Biol. 2012;928:29-38. doi: 10.1007/978-1-62703-008-3_3.

PMID:
22956131
2.

Structure-function based design of small molecule inhibitors targeting Rho family GTPases.

Nassar N, Cancelas J, Zheng J, Williams DA, Zheng Y.

Curr Top Med Chem. 2006;6(11):1109-16. Review.

PMID:
16842149
3.

Targeting rho GTPases by peptidic structures.

Marchioni F, Zheng Y.

Curr Pharm Des. 2009;15(21):2481-7. Review.

PMID:
19601845
4.

Rho GTPases: promising cellular targets for novel anticancer drugs.

Fritz G, Kaina B.

Curr Cancer Drug Targets. 2006 Feb;6(1):1-14. Review.

PMID:
16475973
5.

Approaches of targeting Rho GTPases in cancer drug discovery.

Lin Y, Zheng Y.

Expert Opin Drug Discov. 2015;10(9):991-1010. doi: 10.1517/17460441.2015.1058775. Epub 2015 Jun 18. Review.

6.

The GTP-binding protein Rho.

Ridley AJ.

Int J Biochem Cell Biol. 1997 Nov;29(11):1225-9. Review.

PMID:
9451818
7.

Driving Rho GTPase activity in endothelial cells regulates barrier integrity.

Beckers CM, van Hinsbergh VW, van Nieuw Amerongen GP.

Thromb Haemost. 2010 Jan;103(1):40-55. doi: 10.1160/TH09-06-0403. Epub 2009 Sep 30. Review.

PMID:
20062930
8.

Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.

Tsou PS, Haak AJ, Khanna D, Neubig RR.

Am J Physiol Cell Physiol. 2014 Jul 1;307(1):C2-13. doi: 10.1152/ajpcell.00060.2014. Epub 2014 Apr 16. Review.

9.

Targeting GTPases in Parkinson's disease: comparison to the historic path of kinase drug discovery and perspectives.

Hong L, Sklar LA.

Front Mol Neurosci. 2014 Jun 5;7:52. doi: 10.3389/fnmol.2014.00052. eCollection 2014. Review.

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