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Items: 7

1.

Three-dimensional HepaRG model as an attractive tool for toxicity testing.

Leite SB, Wilk-Zasadna I, Zaldivar JM, Airola E, Reis-Fernandes MA, Mennecozzi M, Guguen-Guillouzo C, Chesne C, Guillou C, Alves PM, Coecke S.

Toxicol Sci. 2012 Nov;130(1):106-16. doi: 10.1093/toxsci/kfs232. Epub 2012 Jul 27.

2.

The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics.

Guillouzo A, Corlu A, Aninat C, Glaise D, Morel F, Guguen-Guillouzo C.

Chem Biol Interact. 2007 May 20;168(1):66-73. Epub 2006 Dec 16. Review.

PMID:
17241619
3.

The HepaRG cell line: a unique in vitro tool for understanding drug metabolism and toxicology in human.

Andersson TB, Kanebratt KP, Kenna JG.

Expert Opin Drug Metab Toxicol. 2012 Jul;8(7):909-20. doi: 10.1517/17425255.2012.685159. Epub 2012 May 8. Review.

PMID:
22568886
4.

New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures.

Gebhardt R, Hengstler JG, Müller D, Glöckner R, Buenning P, Laube B, Schmelzer E, Ullrich M, Utesch D, Hewitt N, Ringel M, Hilz BR, Bader A, Langsch A, Koose T, Burger HJ, Maas J, Oesch F.

Drug Metab Rev. 2003 May-Aug;35(2-3):145-213. Review.

PMID:
12959414
5.

Optimization of the HepaRG cell model for drug metabolism and toxicity studies.

Anthérieu S, Chesné C, Li R, Guguen-Guillouzo C, Guillouzo A.

Toxicol In Vitro. 2012 Dec;26(8):1278-85. doi: 10.1016/j.tiv.2012.05.008. Epub 2012 May 27. Review.

PMID:
22643240
6.

Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies.

Fraczek J, Bolleyn J, Vanhaecke T, Rogiers V, Vinken M.

Arch Toxicol. 2013 Apr;87(4):577-610. doi: 10.1007/s00204-012-0983-3. Epub 2012 Dec 15. Review.

PMID:
23242478
7.

State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology.

Alépée N, Bahinski A, Daneshian M, De Wever B, Fritsche E, Goldberg A, Hansmann J, Hartung T, Haycock J, Hogberg H, Hoelting L, Kelm JM, Kadereit S, McVey E, Landsiedel R, Leist M, Lübberstedt M, Noor F, Pellevoisin C, Petersohn D, Pfannenbecker U, Reisinger K, Ramirez T, Rothen-Rutishauser B, Schäfer-Korting M, Zeilinger K, Zurich MG.

ALTEX. 2014;31(4):441-77. doi: http://dx.doi.org/10.14573/altex1406111. Epub 2014 Jul 14. Review.

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