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Results: 1 to 20 of 27

1.

Group I p21-activated kinases (PAKs) promote tumor cell proliferation and survival through the AKT1 and Raf-MAPK pathways.

Menges CW, Sementino E, Talarchek J, Xu J, Chernoff J, Peterson JR, Testa JR.

Mol Cancer Res. 2012 Sep;10(9):1178-88. Epub 2012 Jul 12.

PMID:
22798428
[PubMed - in process]
Free PMC Article
2.

Pak protein kinases and their role in cancer.

Dummler B, Ohshiro K, Kumar R, Field J.

Cancer Metastasis Rev. 2009 Jun;28(1-2):51-63. doi: 10.1007/s10555-008-9168-1. Review.

PMID:
19165420
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways.

Lim L, Manser E, Leung T, Hall C.

Eur J Biochem. 1996 Dec 1;242(2):171-85. Review.

PMID:
8973630
[PubMed - indexed for MEDLINE]
Free Article
4.

An emerging role for p21-activated kinases (Paks) in viral infections.

Van den Broeke C, Radu M, Chernoff J, Favoreel HW.

Trends Cell Biol. 2010 Mar;20(3):160-9. doi: 10.1016/j.tcb.2009.12.005. Epub 2010 Jan 12. Review.

PMID:
20071173
[PubMed - indexed for MEDLINE]
5.

The p21Rac/Cdc42-activated kinases (PAKs).

Knaus UG, Bokoch GM.

Int J Biochem Cell Biol. 1998 Aug;30(8):857-62. Review.

PMID:
9744077
[PubMed - indexed for MEDLINE]
6.

P21-activated kinases in human cancer.

Vadlamudi RK, Kumar R.

Cancer Metastasis Rev. 2003 Dec;22(4):385-93. Review.

PMID:
12884913
[PubMed - indexed for MEDLINE]
7.

Involvement of Rac/Cdc42/PAK pathway in cytoskeletal rearrangements.

Szczepanowska J.

Acta Biochim Pol. 2009;56(2):225-34. Epub 2009 Jun 10. Review.

PMID:
19513348
[PubMed - indexed for MEDLINE]
Free Article
8.

The emerging importance of group II PAKs.

Wells CM, Jones GE.

Biochem J. 2010 Jan 15;425(3):465-73. doi: 10.1042/BJ20091173. Review.

PMID:
20070256
[PubMed - indexed for MEDLINE]
9.

PAK thread from amoeba to mammals.

Kumar A, Molli PR, Pakala SB, Bui Nguyen TM, Rayala SK, Kumar R.

J Cell Biochem. 2009 Jul 1;107(4):579-85. doi: 10.1002/jcb.22159. Review.

PMID:
19350548
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

UnPAKing the class differences among p21-activated kinases.

Eswaran J, Soundararajan M, Kumar R, Knapp S.

Trends Biochem Sci. 2008 Aug;33(8):394-403. doi: 10.1016/j.tibs.2008.06.002. Epub 2008 Jul 17. Review.

PMID:
18639460
[PubMed - indexed for MEDLINE]
11.

Signalling to cancer cell invasion through PAK family kinases.

Whale A, Hashim FN, Fram S, Jones GE, Wells CM.

Front Biosci (Landmark Ed). 2011 Jan 1;16:849-64. Review.

PMID:
21196207
[PubMed - indexed for MEDLINE]
12.

PAK signaling in oncogenesis.

Molli PR, Li DQ, Murray BW, Rayala SK, Kumar R.

Oncogene. 2009 Jul 16;28(28):2545-55. doi: 10.1038/onc.2009.119. Epub 2009 May 25. Review.

PMID:
19465939
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

p21-activated kinases and gastrointestinal cancer.

He H, Baldwin GS.

Biochim Biophys Acta. 2013 Jan;1833(1):33-9. doi: 10.1016/j.bbamcr.2012.10.015. Epub 2012 Oct 22. Review.

PMID:
23092728
[PubMed - indexed for MEDLINE]
Free Article
14.

p21-activated kinases: three more join the Pak.

Jaffer ZM, Chernoff J.

Int J Biochem Cell Biol. 2002 Jul;34(7):713-7. Review.

PMID:
11950587
[PubMed - indexed for MEDLINE]
15.

A tale of two Paks.

Arias-Romero LE, Chernoff J.

Biol Cell. 2008 Feb;100(2):97-108. doi: 10.1042/BC20070109. Review.

PMID:
18199048
[PubMed - indexed for MEDLINE]
16.

Targeting group II PAKs in cancer and metastasis.

Eswaran J, Soundararajan M, Knapp S.

Cancer Metastasis Rev. 2009 Jun;28(1-2):209-17. doi: 10.1007/s10555-008-9181-4. Review.

PMID:
19160016
[PubMed - indexed for MEDLINE]
17.

PAK as a therapeutic target in gastric cancer.

Li X, Liu F, Li F.

Expert Opin Ther Targets. 2010 Apr;14(4):419-33. doi: 10.1517/14728221003642019. Review.

PMID:
20146633
[PubMed - indexed for MEDLINE]
18.

NF2: the wizardry of merlin.

Xiao GH, Chernoff J, Testa JR.

Genes Chromosomes Cancer. 2003 Dec;38(4):389-99. Review.

PMID:
14566860
[PubMed - indexed for MEDLINE]
19.

Emerging functions of p21-activated kinases in human cancer cells.

Kumar R, Vadlamudi RK.

J Cell Physiol. 2002 Nov;193(2):133-44. Review.

PMID:
12384990
[PubMed - indexed for MEDLINE]
20.

PAKs in human disease.

Chan PM, Manser E.

Prog Mol Biol Transl Sci. 2012;106:171-87. doi: 10.1016/B978-0-12-396456-4.00011-0. Review.

PMID:
22340718
[PubMed - indexed for MEDLINE]

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