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Results: 1 to 20 of 77

1.

The impact of network biology in pharmacology and toxicology.

Panagiotou G, Taboureau O.

SAR QSAR Environ Res. 2012;23(3-4):221-35. doi: 10.1080/1062936X.2012.657237. Epub 2012 Feb 22. Review.

PMID:
22352466
[PubMed - indexed for MEDLINE]
2.

Network analyses in systems pharmacology.

Berger SI, Iyengar R.

Bioinformatics. 2009 Oct 1;25(19):2466-72. doi: 10.1093/bioinformatics/btp465. Epub 2009 Jul 30. Review.

PMID:
19648136
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Toxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies.

Aardema MJ, MacGregor JT.

Mutat Res. 2002 Jan 29;499(1):13-25. Review.

PMID:
11804602
[PubMed - indexed for MEDLINE]
4.

[Network pharmacology and drug discovery].

Wang J, Li XJ.

Sheng Li Ke Xue Jin Zhan. 2011 Aug;42(4):241-5. Review. Chinese.

PMID:
22066413
[PubMed - indexed for MEDLINE]
5.

Unveiling the role of network and systems biology in drug discovery.

Pujol A, Mosca R, Farr├ęs J, Aloy P.

Trends Pharmacol Sci. 2010 Mar;31(3):115-23. doi: 10.1016/j.tips.2009.11.006. Epub 2010 Feb 1. Review.

PMID:
20117850
[PubMed - indexed for MEDLINE]
6.

Systems pharmacology: network analysis to identify multiscale mechanisms of drug action.

Zhao S, Iyengar R.

Annu Rev Pharmacol Toxicol. 2012;52:505-21. doi: 10.1146/annurev-pharmtox-010611-134520. Review.

PMID:
22235860
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Network systems biology for drug discovery.

Arrell DK, Terzic A.

Clin Pharmacol Ther. 2010 Jul;88(1):120-5. doi: 10.1038/clpt.2010.91. Epub 2010 Jun 2. Review.

PMID:
20520604
[PubMed - indexed for MEDLINE]
8.

Proteomics and systems biology: application in drug discovery and development.

Chakravarti B, Mallik B, Chakravarti DN.

Methods Mol Biol. 2010;662:3-28. doi: 10.1007/978-1-60761-800-3_1. Review.

PMID:
20824464
[PubMed - indexed for MEDLINE]
9.

Role of systems pharmacology in understanding drug adverse events.

Berger SI, Iyengar R.

Wiley Interdiscip Rev Syst Biol Med. 2011 Mar-Apr;3(2):129-35. doi: 10.1002/wsbm.114. Epub 2010 Aug 27. Review.

PMID:
20803507
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Informed toxicity assessment in drug discovery: systems-based toxicology.

Mayne JT, Ku WW, Kennedy SP.

Curr Opin Drug Discov Devel. 2006 Jan;9(1):75-83. Review.

PMID:
16445119
[PubMed - indexed for MEDLINE]
11.

Drug discovery in the age of systems biology: the rise of computational approaches for data integration.

Iskar M, Zeller G, Zhao XM, van Noort V, Bork P.

Curr Opin Biotechnol. 2012 Aug;23(4):609-16. doi: 10.1016/j.copbio.2011.11.010. Epub 2011 Dec 5. Review.

PMID:
22153034
[PubMed - indexed for MEDLINE]
12.

Adopting network pharmacology for cancer drug discovery.

Azmi AS.

Curr Drug Discov Technol. 2013 Jun;10(2):95-105. Review.

PMID:
23237672
[PubMed - indexed for MEDLINE]
13.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials.

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Epub 2008 Feb 13. Review.

PMID:
18328408
[PubMed - indexed for MEDLINE]
14.

Systems biology impact on antiepileptic drug discovery.

Margineanu DG.

Epilepsy Res. 2012 Feb;98(2-3):104-15. doi: 10.1016/j.eplepsyres.2011.10.006. Epub 2011 Nov 3. Review.

PMID:
22055355
[PubMed - indexed for MEDLINE]
15.

Systems pharmacology to predict drug toxicity: integration across levels of biological organization.

Bai JP, Abernethy DR.

Annu Rev Pharmacol Toxicol. 2013;53:451-73. doi: 10.1146/annurev-pharmtox-011112-140248. Epub 2012 Nov 5. Review.

PMID:
23140241
[PubMed - indexed for MEDLINE]
16.

Applying systems biology in drug discovery and development.

Galizzi JP, Lockhart BP, Bril A.

Drug Metabol Drug Interact. 2013;28(2):67-78. doi: 10.1515/dmdi-2013-0002. Review.

PMID:
23612649
[PubMed - indexed for MEDLINE]
17.

Systems approaches to polypharmacology and drug discovery.

Boran AD, Iyengar R.

Curr Opin Drug Discov Devel. 2010 May;13(3):297-309. Review.

PMID:
20443163
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Network biology as a new approach to drug discovery.

Lowe JA, Jones P, Wilson DM.

Curr Opin Drug Discov Devel. 2010 Sep;13(5):524-6. Review.

PMID:
20812143
[PubMed - indexed for MEDLINE]
19.

Systems biology tools for toxicology.

Geenen S, Taylor PN, Snoep JL, Wilson ID, Kenna JG, Westerhoff HV.

Arch Toxicol. 2012 Aug;86(8):1251-71. doi: 10.1007/s00204-012-0857-8. Epub 2012 May 9. Review.

PMID:
22569772
[PubMed - indexed for MEDLINE]
20.

Systems-ADME/Tox: resources and network approaches.

Ekins S.

J Pharmacol Toxicol Methods. 2006 Jan-Feb;53(1):38-66. Epub 2005 Jul 27. Review.

PMID:
16054403
[PubMed - indexed for MEDLINE]

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