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Results: 19

1.

Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor.

Liu X, Shi Y, Maag DX, Palma JP, Patterson MJ, Ellis PA, Surber BW, Ready DB, Soni NB, Ladror US, Xu AJ, Iyer R, Harlan JE, Solomon LR, Donawho CK, Penning TD, Johnson EF, Shoemaker AR.

Clin Cancer Res. 2012 Jan 15;18(2):510-23. doi: 10.1158/1078-0432.CCR-11-1973. Epub 2011 Nov 29.

PMID:
22128301
[PubMed - indexed for MEDLINE]
Free Article
2.

Inducing synthetic lethality using PARP inhibitors.

Boss DS, Beijnen JH, Schellens JH.

Curr Clin Pharmacol. 2010 Aug;5(3):192-5. Review.

PMID:
20406170
[PubMed - indexed for MEDLINE]
3.

PARP inhibitors for cancer therapy.

Curtin NJ.

Expert Rev Mol Med. 2005 Mar 15;7(4):1-20. Review.

PMID:
15836799
[PubMed - indexed for MEDLINE]
4.

Appraising iniparib, the PARP inhibitor that never was--what must we learn?

Mateo J, Ong M, Tan DS, Gonzalez MA, de Bono JS.

Nat Rev Clin Oncol. 2013 Dec;10(12):688-96. doi: 10.1038/nrclinonc.2013.177. Epub 2013 Oct 15. Review.

PMID:
24129347
[PubMed - indexed for MEDLINE]
5.

[PARP inhibitors and breast cancer: update and perspectives].

Gonçalves A.

Bull Cancer. 2012 Apr 1;99(4):441-51. doi: 10.1684/bdc.2012.1553. Review. French.

PMID:
22450359
[PubMed - indexed for MEDLINE]
6.

Small-molecule PARP modulators--current status and future therapeutic potential.

Penning TD.

Curr Opin Drug Discov Devel. 2010 Sep;13(5):577-86. Review.

PMID:
20812149
[PubMed - indexed for MEDLINE]
7.

Poly(ADP-ribose) polymerase inhibition: a new direction for BRCA and triple-negative breast cancer?

Plummer R.

Breast Cancer Res. 2011 Aug 16;13(4):218. doi: 10.1186/bcr2877. Review.

PMID:
21884642
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Iniparib, a PARP1 inhibitor for the potential treatment of cancer, including triple-negative breast cancer.

Liang H, Tan AR.

IDrugs. 2010 Sep;13(9):646-56. Review.

PMID:
20799148
[PubMed - indexed for MEDLINE]
9.

Poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors in cancer chemotherapy.

Cepeda V, Fuertes MA, Castilla J, Alonso C, Quevedo C, Soto M, Pérez JM.

Recent Pat Anticancer Drug Discov. 2006 Jan;1(1):39-53. Review.

PMID:
18221025
[PubMed - indexed for MEDLINE]
10.

The potential role and application of PARP inhibitors in cancer treatment.

Chalmers AJ.

Br Med Bull. 2009;89:23-40. doi: 10.1093/bmb/ldp005. Epub 2009 Feb 9. Review.

PMID:
19208614
[PubMed - indexed for MEDLINE]
11.

Poly(ADP-ribosyl)ation polymerases: mechanism and new target of anticancer therapy.

Heitz F, Harter P, Ewald-Riegler N, Papsdorf M, Kommoss S, du Bois A.

Expert Rev Anticancer Ther. 2010 Jul;10(7):1125-36. doi: 10.1586/era.10.53. Review.

PMID:
20645701
[PubMed - indexed for MEDLINE]
12.

PARP inhibitors: new partners in the therapy of cancer and inflammatory diseases.

Peralta-Leal A, Rodríguez-Vargas JM, Aguilar-Quesada R, Rodríguez MI, Linares JL, de Almodóvar MR, Oliver FJ.

Free Radic Biol Med. 2009 Jul 1;47(1):13-26. doi: 10.1016/j.freeradbiomed.2009.04.008. Epub 2009 Apr 10. Review.

PMID:
19362586
[PubMed - indexed for MEDLINE]
13.

PARP inhibitor development for systemic cancer targeting.

Zaremba T, Curtin NJ.

Anticancer Agents Med Chem. 2007 Sep;7(5):515-23. Review.

PMID:
17896912
[PubMed - indexed for MEDLINE]
14.

PARP inhibitors in ovarian cancer: current status and future promise.

Liu JF, Konstantinopoulos PA, Matulonis UA.

Gynecol Oncol. 2014 May;133(2):362-9. doi: 10.1016/j.ygyno.2014.02.039. Epub 2014 Mar 4. Review.

PMID:
24607283
[PubMed - indexed for MEDLINE]
15.

A review of iniparib in ovarian cancer.

Wilkinson-Ryan I, Mutch D.

Expert Opin Investig Drugs. 2013 Mar;22(3):399-405. doi: 10.1517/13543784.2013.772135. Review.

PMID:
23394483
[PubMed - indexed for MEDLINE]
16.

Emergence of rationally designed therapeutic strategies for breast cancer targeting DNA repair mechanisms.

Rowe BP, Glazer PM.

Breast Cancer Res. 2010;12(2):203. doi: 10.1186/bcr2566. Epub 2010 Apr 30. Review.

PMID:
20459590
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

PARP inhibitors: polypharmacology versus selective inhibition.

Ekblad T, Camaioni E, Schüler H, Macchiarulo A.

FEBS J. 2013 Aug;280(15):3563-75. doi: 10.1111/febs.12298. Epub 2013 May 24. Review.

PMID:
23601167
[PubMed - indexed for MEDLINE]
18.

PARP inhibition as a prototype for synthetic lethal screens.

Liu X.

Methods Mol Biol. 2013;986:123-37. doi: 10.1007/978-1-62703-311-4_9. Review.

PMID:
23436410
[PubMed - indexed for MEDLINE]
19.

PARP inhibition: PARP1 and beyond.

Rouleau M, Patel A, Hendzel MJ, Kaufmann SH, Poirier GG.

Nat Rev Cancer. 2010 Apr;10(4):293-301. doi: 10.1038/nrc2812. Epub 2010 Mar 4. Review.

PMID:
20200537
[PubMed - indexed for MEDLINE]
Free PMC Article
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