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Results: 11

1.

TMC310911, a novel human immunodeficiency virus type 1 protease inhibitor, shows in vitro an improved resistance profile and higher genetic barrier to resistance compared with current protease inhibitors.

Dierynck I, Van Marck H, Van Ginderen M, Jonckers TH, Nalam MN, Schiffer CA, Raoof A, Kraus G, Picchio G.

Antimicrob Agents Chemother. 2011 Dec;55(12):5723-31. doi: 10.1128/AAC.00748-11. Epub 2011 Sep 6.

PMID:
21896904
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Resilience to resistance of HIV-1 protease inhibitors: profile of darunavir.

Lefebvre E, Schiffer CA.

AIDS Rev. 2008 Jul-Sep;10(3):131-42. Review.

PMID:
18820715
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

[Resistance to darunavir].

GarcĂ­a Deltoro M.

Enferm Infecc Microbiol Clin. 2008 Oct;26 Suppl 10:51-60. Review. Spanish.

PMID:
19195460
[PubMed - indexed for MEDLINE]
4.

In vitro selection and characterization of VX-478 resistant HIV-1 variants.

Pazhanisamy S, Partaledis JA, Rao BG, Livingston DJ.

Adv Exp Med Biol. 1998;436:75-83. Review.

PMID:
9561202
[PubMed - indexed for MEDLINE]
5.

Resistance to protease inhibitors.

Kuritzkes DR.

J HIV Ther. 2002 Nov;7(4):87-91. Review.

PMID:
12733606
[PubMed - indexed for MEDLINE]
6.

The influence of protease inhibitor resistance profiles on selection of HIV therapy in treatment-naive patients.

Turner D, Schapiro JM, Brenner BG, Wainberg MA.

Antivir Ther. 2004 Jun;9(3):301-14. Review.

PMID:
15259893
[PubMed - indexed for MEDLINE]
7.

Design of HIV protease inhibitors targeting protein backbone: an effective strategy for combating drug resistance.

Ghosh AK, Chapsal BD, Weber IT, Mitsuya H.

Acc Chem Res. 2008 Jan;41(1):78-86. Epub 2007 Aug 28. Review.

PMID:
17722874
[PubMed - indexed for MEDLINE]
8.

Human Immunodeficiency Virus Gag and protease: partners in resistance.

Fun A, Wensing AM, Verheyen J, Nijhuis M.

Retrovirology. 2012 Aug 6;9:63. doi: 10.1186/1742-4690-9-63. Review.

PMID:
22867298
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Darunavir, a conceptually new HIV-1 protease inhibitor for the treatment of drug-resistant HIV.

Ghosh AK, Dawson ZL, Mitsuya H.

Bioorg Med Chem. 2007 Dec 15;15(24):7576-80. Epub 2007 Sep 14. Review.

PMID:
17900913
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Heterocyclic HIV-protease inhibitors.

Calugi C, Guarna A, Trabocchi A.

Curr Med Chem. 2013;20(30):3693-710. Review.

PMID:
23746271
[PubMed - indexed for MEDLINE]
11.

Bis-tetrahydrofuran: a privileged ligand for darunavir and a new generation of hiv protease inhibitors that combat drug resistance.

Ghosh AK, Ramu Sridhar P, Kumaragurubaran N, Koh Y, Weber IT, Mitsuya H.

ChemMedChem. 2006 Sep;1(9):939-50. Review. No abstract available.

PMID:
16927344
[PubMed - indexed for MEDLINE]
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