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Items: 1 to 20 of 27

1.

Dual neuroprotective pathways of a pro-electrophilic compound via HSF-1-activated heat-shock proteins and Nrf2-activated phase 2 antioxidant response enzymes.

Satoh T, Rezaie T, Seki M, Sunico CR, Tabuchi T, Kitagawa T, Yanagitai M, Senzaki M, Kosegawa C, Taira H, McKercher SR, Hoffman JK, Roth GP, Lipton SA.

J Neurochem. 2011 Nov;119(3):569-78. doi: 10.1111/j.1471-4159.2011.07449.x. Epub 2011 Sep 21.

2.

Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs.

Satoh T, McKercher SR, Lipton SA.

Free Radic Biol Med. 2013 Dec;65:645-57. doi: 10.1016/j.freeradbiomed.2013.07.022. Epub 2013 Jul 25. Review.

3.

Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.

Giudice A, Arra C, Turco MC.

Methods Mol Biol. 2010;647:37-74. doi: 10.1007/978-1-60761-738-9_3. Review.

PMID:
20694660
4.
5.

Nrf2/ARE regulated antioxidant gene expression in endothelial and smooth muscle cells in oxidative stress: implications for atherosclerosis and preeclampsia.

Mann GE, Niehueser-Saran J, Watson A, Gao L, Ishii T, de Winter P, Siow RC.

Sheng Li Xue Bao. 2007 Apr 25;59(2):117-27. Review.

6.

Keap1-Nrf2 signaling pathway: mechanisms of regulation and role in protection of cells against toxicity caused by xenobiotics and electrophiles.

Turpaev KT.

Biochemistry (Mosc). 2013 Feb;78(2):111-26. doi: 10.1134/S0006297913020016. Review.

PMID:
23581983
7.

Nrf2 signaling in coordinated activation of antioxidant gene expression.

Jaiswal AK.

Free Radic Biol Med. 2004 May 15;36(10):1199-207. Review.

PMID:
15110384
8.

The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress.

Nguyen T, Yang CS, Pickett CB.

Free Radic Biol Med. 2004 Aug 15;37(4):433-41. Review.

PMID:
15256215
9.

Nrf2 as a novel molecular target for chemoprevention.

Lee JS, Surh YJ.

Cancer Lett. 2005 Jun 28;224(2):171-84. Epub 2004 Nov 11. Review.

PMID:
15914268
10.

Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis.

Li W, Khor TO, Xu C, Shen G, Jeong WS, Yu S, Kong AN.

Biochem Pharmacol. 2008 Dec 1;76(11):1485-9. doi: 10.1016/j.bcp.2008.07.017. Epub 2008 Jul 23. Review.

11.

The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1.

Rhee SG, Bae SH.

Free Radic Biol Med. 2015 Nov;88(Pt B):205-11. doi: 10.1016/j.freeradbiomed.2015.06.007. Epub 2015 Jun 25. Review.

PMID:
26117317
12.

Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular protection in stroke.

Alfieri A, Srivastava S, Siow RC, Modo M, Fraser PA, Mann GE.

J Physiol. 2011 Sep 1;589(17):4125-36. doi: 10.1113/jphysiol.2011.210294. Epub 2011 Jun 6. Review.

13.

Nrf2 defends the lung from oxidative stress.

Cho HY, Reddy SP, Kleeberger SR.

Antioxid Redox Signal. 2006 Jan-Feb;8(1-2):76-87. Review.

PMID:
16487040
15.

Oxidative stress response and Nrf2 signaling in aging.

Zhang H, Davies KJ, Forman HJ.

Free Radic Biol Med. 2015 Nov;88(Pt B):314-36. doi: 10.1016/j.freeradbiomed.2015.05.036. Epub 2015 Jun 9. Review.

PMID:
26066302
16.

Role of dietary pro-oxidants in the maintenance of health and resilience to oxidative stress.

de Roos B, Duthie GG.

Mol Nutr Food Res. 2015 Jul;59(7):1229-48. doi: 10.1002/mnfr.201400568. Epub 2015 Jan 22. Review.

PMID:
25546122
17.

Endogenous Generation and Signaling Actions of Omega-3 Fatty Acid Electrophilic Derivatives.

Cipollina C.

Biomed Res Int. 2015;2015:501792. doi: 10.1155/2015/501792. Epub 2015 Aug 3. Review.

18.

Dual roles of NRF2 in tumor prevention and progression: possible implications in cancer treatment.

Moon EJ, Giaccia A.

Free Radic Biol Med. 2015 Feb;79:292-9. doi: 10.1016/j.freeradbiomed.2014.11.009. Epub 2014 Nov 29. Review.

19.

Chemopreventive role of anthocyanins in atherosclerosis via activation of Nrf2-ARE as an indicator and modulator of redox.

Aboonabi A, Singh I.

Biomed Pharmacother. 2015 May;72:30-6. doi: 10.1016/j.biopha.2015.03.008. Epub 2015 Apr 9. Review.

PMID:
26054672
20.

Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation.

Bai Y, Wang X, Zhao S, Ma C, Cui J, Zheng Y.

Oxid Med Cell Longev. 2015;2015:407580. doi: 10.1155/2015/407580. Epub 2015 Oct 25. Review.

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