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Items: 16

1.

Understanding molecular recognition by G protein βγ subunits on the path to pharmacological targeting.

Lin Y, Smrcka AV.

Mol Pharmacol. 2011 Oct;80(4):551-7. doi: 10.1124/mol.111.073072. Epub 2011 Jul 7. Review.

2.

Interaction of Gbetagamma with RACK1 and other WD40 repeat proteins.

Chen S, Spiegelberg BD, Lin F, Dell EJ, Hamm HE.

J Mol Cell Cardiol. 2004 Aug;37(2):399-406. Review.

PMID:
15276010
3.

G protein betagamma subunits as targets for small molecule therapeutic development.

Smrcka AV, Lehmann DM, Dessal AL.

Comb Chem High Throughput Screen. 2008 Jun;11(5):382-95. Review.

4.

The expanding roles of Gβγ subunits in G protein-coupled receptor signaling and drug action.

Khan SM, Sleno R, Gora S, Zylbergold P, Laverdure JP, Labbé JC, Miller GJ, Hébert TE.

Pharmacol Rev. 2013 Feb 13;65(2):545-77. doi: 10.1124/pr.111.005603. Print 2013 Apr. Review.

5.

Molecular targeting of Gα and Gβγ subunits: a potential approach for cancer therapeutics.

Smrcka AV.

Trends Pharmacol Sci. 2013 May;34(5):290-8. doi: 10.1016/j.tips.2013.02.006. Epub 2013 Apr 1. Review.

6.

Interaction of nucleoside diphosphate kinase B with heterotrimeric G protein betagamma dimers: consequences on G protein activation and stability.

Wieland T.

Naunyn Schmiedebergs Arch Pharmacol. 2007 Feb;374(5-6):373-83. Epub 2007 Jan 3. Review.

PMID:
17200862
7.

Chaperone-mediated assembly of G protein complexes.

Willardson BM, Tracy CM.

Subcell Biochem. 2012;63:131-53. doi: 10.1007/978-94-007-4765-4_8. Review.

PMID:
23161137
8.

Synthesis and assembly of G protein βγ dimers: comparison of in vitro and in vivo studies.

Dingus J, Hildebrandt JD.

Subcell Biochem. 2012;63:155-80. doi: 10.1007/978-94-007-4765-4_9. Review.

PMID:
23161138
9.

The role of Gbetagamma subunits in the organization, assembly, and function of GPCR signaling complexes.

Dupré DJ, Robitaille M, Rebois RV, Hébert TE.

Annu Rev Pharmacol Toxicol. 2009;49:31-56. doi: 10.1146/annurev-pharmtox-061008-103038. Review.

10.

Taking the heart failure battle inside the cell: small molecule targeting of Gβγ subunits.

Kamal FA, Smrcka AV, Blaxall BC.

J Mol Cell Cardiol. 2011 Oct;51(4):462-7. doi: 10.1016/j.yjmcc.2011.01.006. Epub 2011 Jan 21. Review.

11.

G protein βγ subunits: central mediators of G protein-coupled receptor signaling.

Smrcka AV.

Cell Mol Life Sci. 2008 Jul;65(14):2191-214. doi: 10.1007/s00018-008-8006-5. Review.

12.

Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling.

Blumer JB, Smrcka AV, Lanier SM.

Pharmacol Ther. 2007 Mar;113(3):488-506. Epub 2006 Nov 28. Review.

13.

Structural determinants involved in the formation and activation of G protein betagamma dimers.

McIntire WE.

Neurosignals. 2009;17(1):82-99. doi: 10.1159/000186692. Epub 2009 Feb 12. Review.

14.

Function of phosducin-like proteins in G protein signaling and chaperone-assisted protein folding.

Willardson BM, Howlett AC.

Cell Signal. 2007 Dec;19(12):2417-27. Epub 2007 Jun 28. Review.

15.

Emerging non-canonical functions for heterotrimeric G proteins in cellular signaling.

Ahmed SM, Angers S.

J Recept Signal Transduct Res. 2013 Jun;33(3):177-83. doi: 10.3109/10799893.2013.795972. Review.

PMID:
23721574
16.

GPCR mediated regulation of synaptic transmission.

Betke KM, Wells CA, Hamm HE.

Prog Neurobiol. 2012 Mar;96(3):304-21. doi: 10.1016/j.pneurobio.2012.01.009. Epub 2012 Jan 28. Review.

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