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Results: 11

1.

Small molecule microarrays enable the discovery of compounds that bind the Alzheimer's Aβ peptide and reduce its cytotoxicity.

Chen J, Armstrong AH, Koehler AN, Hecht MH.

J Am Chem Soc. 2010 Dec 1;132(47):17015-22. doi: 10.1021/ja107552s. Epub 2010 Nov 9.

PMID:
21062056
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Conformations and biological activities of amyloid beta peptide 25-35.

Millucci L, Ghezzi L, Bernardini G, Santucci A.

Curr Protein Pept Sci. 2010 Feb;11(1):54-67. Review.

PMID:
20201807
[PubMed - indexed for MEDLINE]
3.

Small-molecule inhibitors/modulators of amyloid-β peptide aggregation and toxicity for the treatment of Alzheimer's disease: a patent review (2010 - 2012).

Belluti F, Rampa A, Gobbi S, Bisi A.

Expert Opin Ther Pat. 2013 May;23(5):581-96. doi: 10.1517/13543776.2013.772983. Epub 2013 Feb 21. Review.

PMID:
23425062
[PubMed - indexed for MEDLINE]
4.

Beta amyloid aggregation inhibitors: small molecules as candidate drugs for therapy of Alzheimer's disease.

Re F, Airoldi C, Zona C, Masserini M, La Ferla B, Quattrocchi N, Nicotra F.

Curr Med Chem. 2010;17(27):2990-3006. Review.

PMID:
20629631
[PubMed - indexed for MEDLINE]
5.

Approaches to discovery and characterization of inhibitors of amyloid beta-peptide polymerization.

Findeis MA.

Biochim Biophys Acta. 2000 Jul 26;1502(1):76-84. Review.

PMID:
10899433
[PubMed - indexed for MEDLINE]
Free Article
6.

Small molecule inhibitors of amyloid β peptide aggregation as a potential therapeutic strategy for Alzheimer's disease.

Nie Q, Du XG, Geng MY.

Acta Pharmacol Sin. 2011 May;32(5):545-51. doi: 10.1038/aps.2011.14. Epub 2011 Apr 18. Review.

PMID:
21499284
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Dye-binding assays for evaluation of the effects of small molecule inhibitors on amyloid (aβ) self-assembly.

Jameson LP, Smith NW, Dzyuba SV.

ACS Chem Neurosci. 2012 Nov 21;3(11):807-19. doi: 10.1021/cn300076x. Epub 2012 Aug 6. Review.

PMID:
23173064
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The role of molecular simulations in the development of inhibitors of amyloid β-peptide aggregation for the treatment of Alzheimer's disease.

Lemkul JA, Bevan DR.

ACS Chem Neurosci. 2012 Nov 21;3(11):845-56. doi: 10.1021/cn300091a. Epub 2012 Aug 27. Review.

PMID:
23173066
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Targeting the undruggable proteome: the small molecules of my dreams.

Crews CM.

Chem Biol. 2010 Jun 25;17(6):551-5. doi: 10.1016/j.chembiol.2010.05.011. Review.

PMID:
20609404
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Methods for the elucidation of protein-small molecule interactions.

McFedries A, Schwaid A, Saghatelian A.

Chem Biol. 2013 May 23;20(5):667-73. doi: 10.1016/j.chembiol.2013.04.008. Review.

PMID:
23706633
[PubMed - indexed for MEDLINE]
Free Article
11.

Probing small molecule binding to amyloid fibrils.

Buell AK, Esbjörner EK, Riss PJ, White DA, Aigbirhio FI, Toth G, Welland ME, Dobson CM, Knowles TP.

Phys Chem Chem Phys. 2011 Dec 7;13(45):20044-52. doi: 10.1039/c1cp22283j. Epub 2011 Oct 17. Review.

PMID:
22006124
[PubMed - indexed for MEDLINE]

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