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Items: 1 to 20 of 21

1.

Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.

Khrapunovich-Baine M, Menon V, Verdier-Pinard P, Smith AB 3rd, Angeletti RH, Fiser A, Horwitz SB, Xiao H.

Biochemistry. 2009 Dec 15;48(49):11664-77. doi: 10.1021/bi901351q.

2.

Strategies for the development of novel Taxol-like agents.

Mooberry SL.

Methods Mol Med. 2007;137:289-302. Review.

PMID:
18085237
3.

The structure activity relationship of discodermolide analogues.

Shaw SJ.

Mini Rev Med Chem. 2008 Mar;8(3):276-84. Review.

PMID:
18336347
4.

(+)-discodermolide: a marine natural product against cancer.

De Souza MV.

ScientificWorldJournal. 2004 Jun 11;4:415-36. Review.

5.

Development of practical syntheses of the marine anticancer agents discodermolide and dictyostatin.

Florence GJ, Gardner NM, Paterson I.

Nat Prod Rep. 2008 Apr;25(2):342-75. doi: 10.1039/b705661n. Epub 2008 Feb 27. Review.

PMID:
18389141
6.

The solid state, solution and tubulin-bound conformations of agents that promote microtubule stabilization.

Jiménez-Barbero J, Amat-Guerri F, Snyder JP.

Curr Med Chem Anticancer Agents. 2002 Jan;2(1):91-122. Review.

PMID:
12678753
7.

The clinical development of new mitotic inhibitors that stabilize the microtubule.

Mani S, Macapinlac M Jr, Goel S, Verdier-Pinard D, Fojo T, Rothenberg M, Colevas D.

Anticancer Drugs. 2004 Jul;15(6):553-8. Review.

PMID:
15205596
8.

The binding sites of microtubule-stabilizing agents.

Field JJ, Díaz JF, Miller JH.

Chem Biol. 2013 Mar 21;20(3):301-15. doi: 10.1016/j.chembiol.2013.01.014. Review.

9.

Taxol (paclitaxel): mechanisms of action.

Horwitz SB.

Ann Oncol. 1994;5 Suppl 6:S3-6. Review.

PMID:
7865431
10.

What tubulin drugs tell us about microtubule structure and dynamics.

Amos LA.

Semin Cell Dev Biol. 2011 Dec;22(9):916-26. doi: 10.1016/j.semcdb.2011.09.014. Epub 2011 Oct 5. Review.

PMID:
22001382
11.

Microtubule stabilizing agents: their molecular signaling consequences and the potential for enhancement by drug combination.

Bergstralh DT, Ting JP.

Cancer Treat Rev. 2006 May;32(3):166-79. Epub 2006 Mar 9. Review.

PMID:
16527420
12.

Peloruside A: a lead non-taxoid-site microtubule-stabilizing agent with potential activity against cancer, neurodegeneration, and autoimmune disease.

Kanakkanthara A, Northcote PT, Miller JH.

Nat Prod Rep. 2016 Apr;33(4):549-61. doi: 10.1039/c5np00146c. Epub 2016 Feb 12. Review.

PMID:
26867978
13.

Taccalonolide microtubule stabilizers.

Li J, Risinger AL, Mooberry SL.

Bioorg Med Chem. 2014 Sep 15;22(18):5091-6. doi: 10.1016/j.bmc.2014.01.012. Epub 2014 Jan 15. Review.

14.

Zampanolide and dactylolide: cytotoxic tubulin-assembly agents and promising anticancer leads.

Chen QH, Kingston DG.

Nat Prod Rep. 2014 Sep;31(9):1202-26. doi: 10.1039/c4np00024b. Review.

15.

Microtubule drugs: action, selectivity, and resistance across the kingdoms of life.

Dostál V, Libusová L.

Protoplasma. 2014 Sep;251(5):991-1005. doi: 10.1007/s00709-014-0633-0. Epub 2014 Mar 21. Review.

PMID:
24652407
16.

Tubulins - the target for anticancer therapy.

Vindya NG, Sharma N, Yadav M, Ethiraj KR.

Curr Top Med Chem. 2015;15(1):73-82. Review.

PMID:
25579568
17.

Natural antitubulin agents: importance of 3,4,5-trimethoxyphenyl fragment.

Negi AS, Gautam Y, Alam S, Chanda D, Luqman S, Sarkar J, Khan F, Konwar R.

Bioorg Med Chem. 2015 Feb 1;23(3):373-89. doi: 10.1016/j.bmc.2014.12.027. Epub 2014 Dec 20. Review.

PMID:
25564377
18.

Drug discovery targeting cell division proteins, microtubules and FtsZ.

Ojima I, Kumar K, Awasthi D, Vineberg JG.

Bioorg Med Chem. 2014 Sep 15;22(18):5060-77. doi: 10.1016/j.bmc.2014.02.036. Epub 2014 Mar 5. Review.

19.

Measurement of ligand binding to tubulin by sulfhydryl reactivity.

Begaye A, Sackett DL.

Methods Cell Biol. 2010;95:391-403. doi: 10.1016/S0091-679X(10)95021-8. Review.

PMID:
20466146
20.

Nanotube interactions with microtubules: implications for cancer medicine.

García-Hevia L, Fernández F, Grávalos C, García A, Villegas JC, Fanarraga ML.

Nanomedicine (Lond). 2014 Jul;9(10):1581-8. doi: 10.2217/nnm.14.92. Review.

PMID:
25253503
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