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Results: 1 to 20 of 22

1.

Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability--a point of convergence in parkinsonian neurodegeneration?

Gillardon F.

J Neurochem. 2009 Sep;110(5):1514-22. doi: 10.1111/j.1471-4159.2009.06235.x. Epub 2009 Jun 22.

PMID:
19545277
[PubMed - indexed for MEDLINE]
2.

The LRRK2 G2019S mutation as the cause of Parkinson's disease in Ashkenazi Jews.

Thaler A, Ash E, Gan-Or Z, Orr-Urtreger A, Giladi N.

J Neural Transm. 2009 Nov;116(11):1473-82. doi: 10.1007/s00702-009-0303-0. Review.

PMID:
19756366
[PubMed - indexed for MEDLINE]
3.

LRRK2 and neurodegeneration.

Santpere G, Ferrer I.

Acta Neuropathol. 2009 Mar;117(3):227-46. doi: 10.1007/s00401-008-0478-8. Epub 2009 Jan 14. Review.

PMID:
19142648
[PubMed - indexed for MEDLINE]
4.

Role of LRRK2 kinase activity in the pathogenesis of Parkinson's disease.

Greggio E.

Biochem Soc Trans. 2012 Oct;40(5):1058-62. Review.

PMID:
22988865
[PubMed - indexed for MEDLINE]
5.

The synaptic function of LRRK2.

Lee S, Imai Y, Gehrke S, Liu S, Lu B.

Biochem Soc Trans. 2012 Oct;40(5):1047-51. Review.

PMID:
22988863
[PubMed - indexed for MEDLINE]
6.

Genetic analysis of Parkinson's disease-linked leucine-rich repeat kinase 2.

Tong Y, Shen J.

Biochem Soc Trans. 2012 Oct;40(5):1042-6. Review.

PMID:
22988862
[PubMed - indexed for MEDLINE]
7.

LRRK2 in Parkinson's disease: genetic and clinical studies from patients.

Kumari U, Tan EK.

FEBS J. 2009 Nov;276(22):6455-63. doi: 10.1111/j.1742-4658.2009.07344.x. Epub 2009 Oct 5. Review.

PMID:
19804413
[PubMed - indexed for MEDLINE]
8.

Molecular biology changes associated with LRRK2 mutations in Parkinson's disease.

Lu YW, Tan EK.

J Neurosci Res. 2008 Jul;86(9):1895-901. doi: 10.1002/jnr.21656. Review.

PMID:
18338801
[PubMed - indexed for MEDLINE]
9.

Mouse models for LRRK2 Parkinson's disease.

Xu Q, Shenoy S, Li C.

Parkinsonism Relat Disord. 2012 Jan;18 Suppl 1:S186-9. doi: 10.1016/S1353-8020(11)70058-X. Review.

PMID:
22166430
[PubMed - indexed for MEDLINE]
10.

A trojan horse for Parkinson's disease.

Hu Y, Tong Y.

Sci Signal. 2010 Apr 6;3(116):pe13. doi: 10.1126/scisignal.3116pe13. Review.

PMID:
20371768
[PubMed - indexed for MEDLINE]
11.

Phosphorylation of LRRK2: from kinase to substrate.

Lobbestael E, Baekelandt V, Taymans JM.

Biochem Soc Trans. 2012 Oct;40(5):1102-10. Review.

PMID:
22988873
[PubMed - indexed for MEDLINE]
12.

New biochemical approaches towards understanding the Parkinson's disease-associated kinase, LRRK2.

Liou GY, Gallo KA.

Biochem J. 2009 Oct 23;424(1):e1-3. doi: 10.1042/BJ20091540. Review.

PMID:
19839940
[PubMed - indexed for MEDLINE]
13.

LRRK2 in Parkinson's disease: function in cells and neurodegeneration.

Webber PJ, West AB.

FEBS J. 2009 Nov;276(22):6436-44. doi: 10.1111/j.1742-4658.2009.07342.x. Epub 2009 Oct 5. Review.

PMID:
19804415
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Cellular effects of LRRK2 mutations.

Cookson MR.

Biochem Soc Trans. 2012 Oct;40(5):1070-3. Review.

PMID:
22988867
[PubMed - indexed for MEDLINE]
15.

LRRK2 and vesicle trafficking.

Sanna G, Del Giudice MG, Crosio C, Iaccarino C.

Biochem Soc Trans. 2012 Oct;40(5):1117-22. Review.

PMID:
22988875
[PubMed - indexed for MEDLINE]
16.

LRRK2 signaling pathways: the key to unlocking neurodegeneration?

Berwick DC, Harvey K.

Trends Cell Biol. 2011 May;21(5):257-65. doi: 10.1016/j.tcb.2011.01.001. Epub 2011 Feb 8. Review.

PMID:
21306901
[PubMed - indexed for MEDLINE]
17.

Mechanisms of LRRK2-mediated neurodegeneration.

Tsika E, Moore DJ.

Curr Neurol Neurosci Rep. 2012 Jun;12(3):251-60. doi: 10.1007/s11910-012-0265-8. Review.

PMID:
22441981
[PubMed - indexed for MEDLINE]
18.

Genetic LRRK2 models of Parkinson's disease: Dissecting the pathogenic pathway and exploring clinical applications.

Yue Z, Lachenmayer ML.

Mov Disord. 2011 Jul;26(8):1386-97. doi: 10.1002/mds.23737. Epub 2011 Apr 29. Review.

PMID:
21538530
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

LRRK2 in Parkinson's disease: biochemical functions.

Anand VS, Braithwaite SP.

FEBS J. 2009 Nov;276(22):6428-35. doi: 10.1111/j.1742-4658.2009.07341.x. Epub 2009 Oct 5. Review.

PMID:
19804416
[PubMed - indexed for MEDLINE]
20.

Insights into LRRK2 function and dysfunction from transgenic and knockout rodent models.

Sloan M, Alegre-Abarrategui J, Wade-Martins R.

Biochem Soc Trans. 2012 Oct;40(5):1080-5. Review.

PMID:
22988869
[PubMed - indexed for MEDLINE]

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