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Items: 20

1.

Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response.

Stracker TH, Usui T, Petrini JH.

DNA Repair (Amst). 2009 Sep 2;8(9):1047-54. doi: 10.1016/j.dnarep.2009.04.012. Epub 2009 May 26. Review.

2.

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2.

Reinhardt HC, Yaffe MB.

Curr Opin Cell Biol. 2009 Apr;21(2):245-55. doi: 10.1016/j.ceb.2009.01.018. Epub 2009 Feb 21. Review.

3.

Analysing the DNA damage and replication checkpoints in DT40 cells.

Rainey MD, Zachos G, Gillespie DA.

Subcell Biochem. 2006;40:107-17. Review.

PMID:
17623903
4.

Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways.

Rhind N, Russell P.

J Cell Sci. 2000 Nov;113 ( Pt 22):3889-96. Review.

5.

Checkpoint kinase inhibitors: a patent review (2009 - 2010).

Lainchbury M, Collins I.

Expert Opin Ther Pat. 2011 Aug;21(8):1191-210. doi: 10.1517/13543776.2011.586632. Epub 2011 May 20. Review.

PMID:
21599421
6.

The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer.

Smith J, Tho LM, Xu N, Gillespie DA.

Adv Cancer Res. 2010;108:73-112. doi: 10.1016/B978-0-12-380888-2.00003-0. Review.

PMID:
21034966
7.

Targeting chk2 kinase: molecular interaction maps and therapeutic rationale.

Pommier Y, Sordet O, Rao VA, Zhang H, Kohn KW.

Curr Pharm Des. 2005;11(22):2855-72. Review.

PMID:
16101442
8.

The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability.

Chen Y, Poon RY.

Front Biosci. 2008 May 1;13:5016-29. Review.

PMID:
18508566
9.

Protein kinases that regulate chromosome stability and their downstream targets.

Nojima H.

Genome Dyn. 2006;1:131-48. doi: 10.1159/000092505. Review.

PMID:
18724058
10.

Chk1 in the DNA damage response: conserved roles from yeasts to mammals.

Chen Y, Sanchez Y.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):1025-32. Review.

PMID:
15279789
11.

Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication.

Sørensen CS, Syljuåsen RG.

Nucleic Acids Res. 2012 Jan;40(2):477-86. doi: 10.1093/nar/gkr697. Epub 2011 Sep 21. Review.

12.

Mechanisms of ATR-mediated checkpoint signalling.

Smits VA, Warmerdam DO, Martin Y, Freire R.

Front Biosci (Landmark Ed). 2010 Jun 1;15:840-53. Review.

PMID:
20515729
13.

Checkpoint kinase inhibitors: a review of the patent literature.

Janetka JW, Ashwell S.

Expert Opin Ther Pat. 2009 Feb;19(2):165-97. doi: 10.1517/13543770802653622. Review.

PMID:
19441917
14.

Eukaryotic DNA damage checkpoint activation in response to double-strand breaks.

Finn K, Lowndes NF, Grenon M.

Cell Mol Life Sci. 2012 May;69(9):1447-73. doi: 10.1007/s00018-011-0875-3. Epub 2011 Nov 15. Review.

PMID:
22083606
15.

New insights into checkpoint kinase 1 in the DNA damage response signaling network.

Dai Y, Grant S.

Clin Cancer Res. 2010 Jan 15;16(2):376-83. doi: 10.1158/1078-0432.CCR-09-1029. Epub 2010 Jan 12. Review.

16.

Targeting DNA checkpoint kinases in cancer therapy.

Zhou BB, Anderson HJ, Roberge M.

Cancer Biol Ther. 2003 Jul-Aug;2(4 Suppl 1):S16-22. Review.

PMID:
14508077
17.

Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy?

Goto H, Izawa I, Li P, Inagaki M.

Cancer Sci. 2012 Jul;103(7):1195-200. doi: 10.1111/j.1349-7006.2012.02280.x. Epub 2012 Apr 23. Review.

18.

Allosteric protein kinase regulation by pseudokinases: insights from STRAD.

Rajakulendran T, Sicheri F.

Sci Signal. 2010 Mar 2;3(111):pe8. doi: 10.1126/scisignal.3111pe8. Review.

PMID:
20197543
19.

Integration of stress signals by homeodomain interacting protein kinases.

Schmitz ML, Rodriguez-Gil A, Hornung J.

Biol Chem. 2014 Apr;395(4):375-86. doi: 10.1515/hsz-2013-0264. Review.

PMID:
24225127
20.

When genome integrity and cell cycle decisions collide: roles of polo kinases in cellular adaptation to DNA damage.

Serrano D, D'Amours D.

Syst Synth Biol. 2014 Sep;8(3):195-203. doi: 10.1007/s11693-014-9151-9. Epub 2014 Jul 27. Review.

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