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Items: 1 to 20 of 30

1.

JAK mutations in high-risk childhood acute lymphoblastic leukemia.

Mullighan CG, Zhang J, Harvey RC, Collins-Underwood JR, Schulman BA, Phillips LA, Tasian SK, Loh ML, Su X, Liu W, Devidas M, Atlas SR, Chen IM, Clifford RJ, Gerhard DS, Carroll WL, Reaman GH, Smith M, Downing JR, Hunger SP, Willman CL.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9414-8. doi: 10.1073/pnas.0811761106. Epub 2009 May 22.

2.

The molecular genetic makeup of acute lymphoblastic leukemia.

Mullighan CG.

Hematology Am Soc Hematol Educ Program. 2012;2012:389-96. doi: 10.1182/asheducation-2012.1.389. Review.

3.

Beyond Philadelphia: 'Ph-like' B cell precursor acute lymphoblastic leukemias - diagnostic challenges and therapeutic promises.

Izraeli S.

Curr Opin Hematol. 2014 Jul;21(4):289-96. doi: 10.1097/MOH.0000000000000050. Review.

PMID:
24848770
4.

Mining for JAK-STAT mutations in cancer.

Constantinescu SN, Girardot M, Pecquet C.

Trends Biochem Sci. 2008 Mar;33(3):122-31. doi: 10.1016/j.tibs.2007.12.002. Review.

PMID:
18291658
5.

Lymphoid malignancies: Another face to the Janus kinases.

Scott LM.

Blood Rev. 2013 Mar;27(2):63-70. doi: 10.1016/j.blre.2012.12.004. Epub 2013 Jan 20. Review.

PMID:
23340138
6.

Genomic profiling of high-risk acute lymphoblastic leukemia.

Collins-Underwood JR, Mullighan CG.

Leukemia. 2010 Oct;24(10):1676-85. doi: 10.1038/leu.2010.177. Epub 2010 Aug 26. Review.

PMID:
20739952
7.

JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies.

Vainchenker W, Dusa A, Constantinescu SN.

Semin Cell Dev Biol. 2008 Aug;19(4):385-93. doi: 10.1016/j.semcdb.2008.07.002. Epub 2008 Jul 17. Review.

PMID:
18682296
8.

The molecular regulation of Janus kinase (JAK) activation.

Babon JJ, Lucet IS, Murphy JM, Nicola NA, Varghese LN.

Biochem J. 2014 Aug 15;462(1):1-13. doi: 10.1042/BJ20140712. Review.

9.

[Therapeutic strategies for childhood high-risk acute lymphoblastic leukemia].

Lu XT.

Beijing Da Xue Xue Bao. 2013 Apr 18;45(2):327-32. Review. Chinese.

10.

JAK/STAT signaling in hematological malignancies.

Vainchenker W, Constantinescu SN.

Oncogene. 2013 May 23;32(21):2601-13. doi: 10.1038/onc.2012.347. Epub 2012 Aug 6. Review.

PMID:
22869151
11.

JAK and MPL mutations in myeloid malignancies.

Tefferi A.

Leuk Lymphoma. 2008 Mar;49(3):388-97. doi: 10.1080/10428190801895360. Review.

PMID:
18297515
12.

The use of structural biology in Janus kinase targeted drug discovery.

Alicea-Velázquez NL, Boggon TJ.

Curr Drug Targets. 2011 Apr;12(4):546-55. Review.

13.

Activating Janus kinase pseudokinase domain mutations in myeloproliferative and other blood cancers.

Constantinescu SN, Leroy E, Gryshkova V, Pecquet C, Dusa A.

Biochem Soc Trans. 2013 Aug;41(4):1048-54. doi: 10.1042/BST20130084. Review.

PMID:
23863177
14.

Genomic profiling of B-progenitor acute lymphoblastic leukemia.

Mullighan CG.

Best Pract Res Clin Haematol. 2011 Dec;24(4):489-503. doi: 10.1016/j.beha.2011.09.004. Epub 2011 Nov 6. Review.

15.

How new advances in genetic analysis are influencing the understanding and treatment of childhood acute leukemia.

Roberts KG, Mullighan CG.

Curr Opin Pediatr. 2011 Feb;23(1):34-40. doi: 10.1097/MOP.0b013e3283426260. Review.

PMID:
21169835
16.

Improving outcomes for high-risk ALL: translating new discoveries into clinical care.

Hunger SP, Raetz EA, Loh ML, Mullighan CG.

Pediatr Blood Cancer. 2011 Jun;56(6):984-93. doi: 10.1002/pbc.22996. Epub 2011 Feb 15. Review.

PMID:
21370430
17.

Understanding the biology of CRLF2-overexpressing acute lymphoblastic leukemia.

Tasian SK, Loh ML.

Crit Rev Oncog. 2011;16(1-2):13-24. Review.

18.

[Research advances in the role of JAK2 mutations in acute leukemia].

Zhang HY, Zhai XW.

Zhongguo Dang Dai Er Ke Za Zhi. 2015 Jun;17(6):644-9. Review. Chinese.

19.
20.

JAK3 pathway is constitutively active in B-lineage acute lymphoblastic leukemia.

Uckun FM, Pitt J, Qazi S.

Expert Rev Anticancer Ther. 2011 Jan;11(1):37-48. doi: 10.1586/era.10.203. Epub 2010 Nov 11. Review.

PMID:
21070101
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