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Results: 1 to 20 of 22

1.

GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.

Nolan-Stevaux O, Lau J, Truitt ML, Chu GC, Hebrok M, Fernández-Zapico ME, Hanahan D.

Genes Dev. 2009 Jan 1;23(1):24-36. doi: 10.1101/gad.1753809.

PMID:
19136624
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.

Morris JP 4th, Wang SC, Hebrok M.

Nat Rev Cancer. 2010 Oct;10(10):683-95. doi: 10.1038/nrc2899. Epub 2010 Sep 3. Review.

PMID:
20814421
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Shh signaling and pancreatic cancer: implications for therapy?

Morton JP, Lewis BC.

Cell Cycle. 2007 Jul 1;6(13):1553-7. Epub 2007 May 18. Review.

PMID:
17611415
[PubMed - indexed for MEDLINE]
Free Article
4.

Pathogenesis of pancreatic cancer: lessons from animal models.

Murtaugh LC.

Toxicol Pathol. 2014 Jan;42(1):217-28. doi: 10.1177/0192623313508250. Epub 2013 Oct 31. Review.

PMID:
24178582
[PubMed - indexed for MEDLINE]
5.

The roles of FOXM1 in pancreatic stem cells and carcinogenesis.

Quan M, Wang P, Cui J, Gao Y, Xie K.

Mol Cancer. 2013 Dec 10;12:159. doi: 10.1186/1476-4598-12-159. Review.

PMID:
24325450
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Primers on molecular pathways GLI: more than just Hedgehog?

Fernández-Zapico ME.

Pancreatology. 2008;8(3):227-9. doi: 10.1159/000134271. Epub 2008 May 22. Review.

PMID:
18497536
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

KRAS: feeding pancreatic cancer proliferation.

Bryant KL, Mancias JD, Kimmelman AC, Der CJ.

Trends Biochem Sci. 2014 Feb;39(2):91-100. doi: 10.1016/j.tibs.2013.12.004. Epub 2014 Jan 2. Review.

PMID:
24388967
[PubMed - indexed for MEDLINE]
8.

Oncogenic KRAS signalling in pancreatic cancer.

Eser S, Schnieke A, Schneider G, Saur D.

Br J Cancer. 2014 Aug 26;111(5):817-22. doi: 10.1038/bjc.2014.215. Epub 2014 Apr 22. Review.

PMID:
24755884
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Inhibition of Hedgehog signaling in the gastrointestinal tract: targeting the cancer microenvironment.

Merchant JL, Saqui-Salces M.

Cancer Treat Rev. 2014 Feb;40(1):12-21. doi: 10.1016/j.ctrv.2013.08.003. Epub 2013 Aug 13. Review.

PMID:
24007940
[PubMed - indexed for MEDLINE]
10.

Cancer cell dormancy in novel mouse models for reversible pancreatic cancer: a lingering challenge in the development of targeted therapies.

Lin WC, Rajbhandari N, Wagner KU.

Cancer Res. 2014 Apr 15;74(8):2138-43. doi: 10.1158/0008-5472.CAN-13-3437. Epub 2014 Mar 26. Review.

PMID:
24670819
[PubMed - indexed for MEDLINE]
11.

Role of protein kinase D signaling in pancreatic cancer.

Guha S, Tanasanvimon S, Sinnett-Smith J, Rozengurt E.

Biochem Pharmacol. 2010 Dec 15;80(12):1946-54. doi: 10.1016/j.bcp.2010.07.002. Epub 2010 Jul 16. Review.

PMID:
20621068
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Obesity, autophagy and the pathogenesis of liver and pancreatic cancers.

Aghajan M, Li N, Karin M.

J Gastroenterol Hepatol. 2012 Mar;27 Suppl 2:10-4. doi: 10.1111/j.1440-1746.2011.07008.x. Review.

PMID:
22320909
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Ras activity in acinar cells links chronic pancreatitis and pancreatic cancer.

Logsdon CD, Ji B.

Clin Gastroenterol Hepatol. 2009 Nov;7(11 Suppl):S40-3. doi: 10.1016/j.cgh.2009.07.040. Review.

PMID:
19896097
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Pancreatic cancer tumour initiating cells: the molecular regulation and therapeutic values.

Ni X, Long J, Cen P, Chen L, Yang J, Li M.

J Cell Mol Med. 2012 May;16(5):988-94. doi: 10.1111/j.1582-4934.2011.01478.x. Review.

PMID:
22050663
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The role of inflammation in pancreatic cancer.

Hausmann S, Kong B, Michalski C, Erkan M, Friess H.

Adv Exp Med Biol. 2014;816:129-51. doi: 10.1007/978-3-0348-0837-8_6. Review.

PMID:
24818722
[PubMed - indexed for MEDLINE]
16.

Metabolism addiction in pancreatic cancer.

Blum R, Kloog Y.

Cell Death Dis. 2014 Feb 20;5:e1065. doi: 10.1038/cddis.2014.38. Review.

PMID:
24556680
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Sonic hedgehog signaling in Basal cell nevus syndrome.

Athar M, Li C, Kim AL, Spiegelman VS, Bickers DR.

Cancer Res. 2014 Sep 15;74(18):4967-75. doi: 10.1158/0008-5472.CAN-14-1666. Epub 2014 Aug 29. Review.

PMID:
25172843
[PubMed - in process]
18.

Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis.

Hogenson T, Lauth M, Pasca diMagliano M, Fernandez-Zapico M.

F1000Res. 2014 Oct 8;3:238. doi: 10.12688/f1000research.5324.1. eCollection 2014. Review.

PMID:
25352983
[PubMed]
Free PMC Article
19.

The secret origins and surprising fates of pancreas tumors.

Bailey JM, DelGiorno KE, Crawford HC.

Carcinogenesis. 2014 Jul;35(7):1436-40. doi: 10.1093/carcin/bgu056. Epub 2014 Feb 28. Review.

PMID:
24583923
[PubMed - indexed for MEDLINE]
20.

Neurotransmitter receptors as central regulators of pancreatic cancer.

Schuller HM, Al-Wadei HA.

Future Oncol. 2010 Feb;6(2):221-8. doi: 10.2217/fon.09.171. Review.

PMID:
20146581
[PubMed - indexed for MEDLINE]
Free PMC Article

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