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Results: 13

1.

A competitive inhibitor traps LeuT in an open-to-out conformation.

Singh SK, Piscitelli CL, Yamashita A, Gouaux E.

Science. 2008 Dec 12;322(5908):1655-61. doi: 10.1126/science.1166777.

PMID:
19074341
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

How LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transporters.

Penmatsa A, Gouaux E.

J Physiol. 2014 Mar 1;592(Pt 5):863-9. doi: 10.1113/jphysiol.2013.259051. Epub 2013 Jul 22. Review.

PMID:
23878376
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Substrate and drug binding sites in LeuT.

Nyola A, Karpowich NK, Zhen J, Marden J, Reith ME, Wang DN.

Curr Opin Struct Biol. 2010 Aug;20(4):415-22. doi: 10.1016/j.sbi.2010.05.007. Epub 2010 Jun 16. Review.

PMID:
20739005
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Mechanistic aspects of sodium-binding sites in LeuT-like fold symporters.

Perez C, Ziegler C.

Biol Chem. 2013 May;394(5):641-8. doi: 10.1515/hsz-2012-0336. Review.

PMID:
23362203
[PubMed - indexed for MEDLINE]
5.

What is an antidepressant binding site doing in a bacterial transporter?

Rudnick G.

ACS Chem Biol. 2007 Sep 21;2(9):606-9. Review.

PMID:
17894444
[PubMed - indexed for MEDLINE]
6.

Secondary transport of amino acids in prokaryotes.

Jung H, Pirch T, Hilger D.

J Membr Biol. 2006;213(2):119-33. Epub 2007 Apr 6. Review.

PMID:
17417701
[PubMed - indexed for MEDLINE]
7.

LeuT: a prokaryotic stepping stone on the way to a eukaryotic neurotransmitter transporter structure.

Singh SK.

Channels (Austin). 2008 Sep-Oct;2(5):380-9. Review.

PMID:
19066470
[PubMed - indexed for MEDLINE]
Free Article
8.

Cytoplasmic permeation pathway of neurotransmitter transporters.

Rudnick G.

Biochemistry. 2011 Sep 6;50(35):7462-75. doi: 10.1021/bi200926b. Epub 2011 Aug 10. Review.

PMID:
21774491
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Amino acid secondary transporters: toward a common transport mechanism.

Schweikhard ES, Ziegler CM.

Curr Top Membr. 2012;70:1-28. doi: 10.1016/B978-0-12-394316-3.00001-6. Review.

PMID:
23177982
[PubMed - indexed for MEDLINE]
10.

Emerging structure-function relationships defining monoamine NSS transporter substrate and ligand affinity.

Wang CI, Lewis RJ.

Biochem Pharmacol. 2010 Apr 15;79(8):1083-91. doi: 10.1016/j.bcp.2009.11.019. Epub 2009 Nov 30. Review.

PMID:
19954741
[PubMed - indexed for MEDLINE]
11.

The Na⁺/L-proline transporter PutP.

Jung H, Hilger D, Raba M.

Front Biosci (Landmark Ed). 2012 Jan 1;17:745-59. Review.

PMID:
22201772
[PubMed - indexed for MEDLINE]
12.

The use of LeuT as a model in elucidating binding sites for substrates and inhibitors in neurotransmitter transporters.

Loland CJ.

Biochim Biophys Acta. 2015 Mar;1850(3):500-510. doi: 10.1016/j.bbagen.2014.04.011. Epub 2014 Apr 24. Review.

PMID:
24769398
[PubMed - as supplied by publisher]
13.

Structural perspectives on secondary active transporters.

Boudker O, Verdon G.

Trends Pharmacol Sci. 2010 Sep;31(9):418-26. doi: 10.1016/j.tips.2010.06.004. Epub 2010 Jul 23. Review.

PMID:
20655602
[PubMed - indexed for MEDLINE]
Free PMC Article
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