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Results: 17

1.

Inhibitors of mammalian acetyl-CoA carboxylase.

Corbett JW, Harwood JH Jr.

Recent Pat Cardiovasc Drug Discov. 2007 Nov;2(3):162-80. Review.

PMID:
18221116
[PubMed - indexed for MEDLINE]
2.

Treating the metabolic syndrome: acetyl-CoA carboxylase inhibition.

Harwood HJ Jr.

Expert Opin Ther Targets. 2005 Apr;9(2):267-81. Review.

PMID:
15934915
[PubMed - indexed for MEDLINE]
3.

Acetyl-CoA carboxylase inhibition for the treatment of metabolic syndrome.

Harwood HJ Jr.

Curr Opin Investig Drugs. 2004 Mar;5(3):283-9. Review.

PMID:
15083594
[PubMed - indexed for MEDLINE]
4.

Review of recent acetyl-CoA carboxylase inhibitor patents: mid-2007-2008.

Corbett JW.

Expert Opin Ther Pat. 2009 Jul;19(7):943-56. doi: 10.1517/13543770902862180. Review.

PMID:
19552511
[PubMed - indexed for MEDLINE]
5.

Acetyl-coenzyme A carboxylase: crucial metabolic enzyme and attractive target for drug discovery.

Tong L.

Cell Mol Life Sci. 2005 Aug;62(16):1784-803. Review.

PMID:
15968460
[PubMed - indexed for MEDLINE]
6.

Targeting acetyl-CoA carboxylases: small molecular inhibitors and their therapeutic potential.

Luo DX, Tong DJ, Rajput S, Wang C, Liao DF, Cao D, Maser E.

Recent Pat Anticancer Drug Discov. 2012 May 1;7(2):168-84. Review.

PMID:
22339356
[PubMed - indexed for MEDLINE]
7.

Regulatory enzymes of mitochondrial beta-oxidation as targets for treatment of the metabolic syndrome.

Schreurs M, Kuipers F, van der Leij FR.

Obes Rev. 2010 May;11(5):380-8. doi: 10.1111/j.1467-789X.2009.00642.x. Epub 2009 Aug 20. Review.

PMID:
19694967
[PubMed - indexed for MEDLINE]
8.

Structure, function and selective inhibition of bacterial acetyl-coa carboxylase.

Polyak SW, Abell AD, Wilce MC, Zhang L, Booker GW.

Appl Microbiol Biotechnol. 2012 Feb;93(3):983-92. doi: 10.1007/s00253-011-3796-z. Epub 2011 Dec 20. Review.

PMID:
22183085
[PubMed - indexed for MEDLINE]
9.

Acetyl-CoA carboxylase-a as a novel target for cancer therapy.

Wang C, Rajput S, Watabe K, Liao DF, Cao D.

Front Biosci (Schol Ed). 2010 Jan 1;2:515-26. Review.

PMID:
20036965
[PubMed - indexed for MEDLINE]
10.

Lipogenic enzymes as therapeutic targets for obesity and diabetes.

Lenhard JM.

Curr Pharm Des. 2011;17(4):325-31. Review.

PMID:
21375498
[PubMed - indexed for MEDLINE]
11.

Modulation of fatty acid metabolism as a potential approach to the treatment of obesity and the metabolic syndrome.

Kusunoki J, Kanatani A, Moller DE.

Endocrine. 2006 Feb;29(1):91-100. Review.

PMID:
16622296
[PubMed - indexed for MEDLINE]
12.

Chemical genetics of acetyl-CoA carboxylases.

Zu X, Zhong J, Luo D, Tan J, Zhang Q, Wu Y, Liu J, Cao R, Wen G, Cao D.

Molecules. 2013 Jan 28;18(2):1704-19. doi: 10.3390/molecules18021704. Review.

PMID:
23358327
[PubMed - indexed for MEDLINE]
Free Article
13.

Acetyl-coenzyme A carboxylases: versatile targets for drug discovery.

Tong L, Harwood HJ Jr.

J Cell Biochem. 2006 Dec 15;99(6):1476-88. Review.

PMID:
16983687
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Role of malonyl-CoA in heart disease and the hypothalamic control of obesity.

Folmes CD, Lopaschuk GD.

Cardiovasc Res. 2007 Jan 15;73(2):278-87. Epub 2006 Oct 20. Review.

PMID:
17126822
[PubMed - indexed for MEDLINE]
Free Article
15.

The regulation of acetyl-CoA carboxylase--a potential target for the action of hypolipidemic agents.

Munday MR, Hemingway CJ.

Adv Enzyme Regul. 1999;39:205-34. Review.

PMID:
10470374
[PubMed - indexed for MEDLINE]
16.

Regulation of acetyl-CoA carboxylase.

Brownsey RW, Boone AN, Elliott JE, Kulpa JE, Lee WM.

Biochem Soc Trans. 2006 Apr;34(Pt 2):223-7. Review.

PMID:
16545081
[PubMed - indexed for MEDLINE]
17.

The 1993 Merck Frosst Award. Acetyl-CoA carboxylase: an important regulator of fatty acid oxidation in the heart.

Lopaschuk GD, Gamble J.

Can J Physiol Pharmacol. 1994 Oct;72(10):1101-9. Review.

PMID:
7882173
[PubMed - indexed for MEDLINE]

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