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Results: 6

1.

Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1.

Satoh T, Kosaka K, Itoh K, Kobayashi A, Yamamoto M, Shimojo Y, Kitajima C, Cui J, Kamins J, Okamoto S, Izumi M, Shirasawa T, Lipton SA.

J Neurochem. 2008 Feb;104(4):1116-31. Epub 2007 Nov 6.

PMID:
17995931
[PubMed - indexed for MEDLINE]
2.

Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution.

Taguchi K, Motohashi H, Yamamoto M.

Genes Cells. 2011 Feb;16(2):123-40. doi: 10.1111/j.1365-2443.2010.01473.x. Review.

PMID:
21251164
[PubMed - indexed for MEDLINE]
3.

Chemistry of the cysteine sensors in Kelch-like ECH-associated protein 1.

Holland R, Fishbein JC.

Antioxid Redox Signal. 2010 Dec 1;13(11):1749-61. doi: 10.1089/ars.2010.3273. Epub 2010 Aug 17. Review.

PMID:
20486763
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.

Giudice A, Arra C, Turco MC.

Methods Mol Biol. 2010;647:37-74. doi: 10.1007/978-1-60761-738-9_3. Review.

PMID:
20694660
[PubMed - indexed for MEDLINE]
5.

Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals.

Surh YJ, Kundu JK, Na HK.

Planta Med. 2008 Oct;74(13):1526-39. doi: 10.1055/s-0028-1088302. Epub 2008 Oct 20. Review.

PMID:
18937164
[PubMed - indexed for MEDLINE]
6.

The Nrf2-ARE pathway: a valuable therapeutic target for the treatment of neurodegenerative diseases.

Joshi G, Johnson JA.

Recent Pat CNS Drug Discov. 2012 Dec;7(3):218-29. Review.

PMID:
22742419
[PubMed - indexed for MEDLINE]
Free PMC Article

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