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Results: 1 to 20 of 83

1.

Neurorescue activity, APP regulation and amyloid-beta peptide reduction by novel multi-functional brain permeable iron- chelating- antioxidants, M-30 and green tea polyphenol, EGCG.

Avramovich-Tirosh Y, Reznichenko L, Mit T, Zheng H, Fridkin M, Weinreb O, Mandel S, Youdim MB.

Curr Alzheimer Res. 2007 Sep;4(4):403-11.

PMID:
17908043
[PubMed - indexed for MEDLINE]
2.

Implications of co-morbidity for etiology and treatment of neurodegenerative diseases with multifunctional neuroprotective-neurorescue drugs; ladostigil.

Youdim MB, Amit T, Bar-Am O, Weinreb O, Yogev-Falach M.

Neurotox Res. 2006 Dec;10(3-4):181-92. Review.

PMID:
17197368
[PubMed - indexed for MEDLINE]
3.
4.
5.

Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: special reference to epigallocatechin gallate (EGCG).

Mandel SA, Amit T, Kalfon L, Reznichenko L, Weinreb O, Youdim MB.

J Alzheimers Dis. 2008 Oct;15(2):211-22. Review.

PMID:
18953110
[PubMed - indexed for MEDLINE]
6.

Simultaneous manipulation of multiple brain targets by green tea catechins: a potential neuroprotective strategy for Alzheimer and Parkinson diseases.

Mandel SA, Amit T, Weinreb O, Reznichenko L, Youdim MB.

CNS Neurosci Ther. 2008 Winter;14(4):352-65. doi: 10.1111/j.1755-5949.2008.00060.x. Review.

PMID:
19040558
[PubMed - indexed for MEDLINE]
7.

Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: implications for neurodegenerative diseases.

Mandel S, Weinreb O, Amit T, Youdim MB.

J Neurochem. 2004 Mar;88(6):1555-69. Review. Erratum in: J Neurochem. 2004 Apr;89(2):527.

PMID:
15009657
[PubMed - indexed for MEDLINE]
8.

Involvement of multiple survival signal transduction pathways in the neuroprotective, neurorescue and APP processing activity of rasagiline and its propargyl moiety.

Weinreb O, Amit T, Bar-Am O, Sagi Y, Mandel S, Youdim MB.

J Neural Transm Suppl. 2006;(70):457-65. Review.

PMID:
17017568
[PubMed - indexed for MEDLINE]
9.

Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway.

Mandel SA, Avramovich-Tirosh Y, Reznichenko L, Zheng H, Weinreb O, Amit T, Youdim MB.

Neurosignals. 2005;14(1-2):46-60. Review.

PMID:
15956814
[PubMed - indexed for MEDLINE]
10.

Multifunctional neuroprotective derivatives of rasagiline as anti-Alzheimer's disease drugs.

Weinreb O, Mandel S, Bar-Am O, Yogev-Falach M, Avramovich-Tirosh Y, Amit T, Youdim MB.

Neurotherapeutics. 2009 Jan;6(1):163-74. doi: 10.1016/j.nurt.2008.10.030. Review.

PMID:
19110207
[PubMed - indexed for MEDLINE]
11.

Green tea catechins as brain-permeable, non toxic iron chelators to "iron out iron" from the brain.

Mandel S, Weinreb O, Reznichenko L, Kalfon L, Amit T.

J Neural Transm Suppl. 2006;(71):249-57. Review.

PMID:
17447435
[PubMed - indexed for MEDLINE]
12.

Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders.

Mandel S, Amit T, Reznichenko L, Weinreb O, Youdim MB.

Mol Nutr Food Res. 2006 Feb;50(2):229-34. Review.

PMID:
16470637
[PubMed - indexed for MEDLINE]
13.

The path from anti Parkinson drug selegiline and rasagiline to multifunctional neuroprotective anti Alzheimer drugs ladostigil and m30.

Youdim MB.

Curr Alzheimer Res. 2006 Dec;3(5):541-50. Review.

PMID:
17168653
[PubMed - indexed for MEDLINE]
14.

Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases.

Weinreb O, Mandel S, Amit T, Youdim MB.

J Nutr Biochem. 2004 Sep;15(9):506-16. Review.

PMID:
15350981
[PubMed - indexed for MEDLINE]
15.

Metal and inflammatory targets for Alzheimer's disease.

Rogers JT, Lahiri DK.

Curr Drug Targets. 2004 Aug;5(6):535-51. Review.

PMID:
15270200
[PubMed - indexed for MEDLINE]
16.

The redox chemistry of the Alzheimer's disease amyloid beta peptide.

Smith DG, Cappai R, Barnham KJ.

Biochim Biophys Acta. 2007 Aug;1768(8):1976-90. Epub 2007 Feb 9. Review.

PMID:
17433250
[PubMed - indexed for MEDLINE]
Free Article
17.

Physiological and pathological aspects of Abeta in iron homeostasis via 5'UTR in the APP mRNA and the therapeutic use of iron-chelators.

Avramovich-Tirosh Y, Amit T, Bar-Am O, Weinreb O, Youdim MB.

BMC Neurosci. 2008 Dec 3;9 Suppl 2:S2. doi: 10.1186/1471-2202-9-S2-S2. Review.

PMID:
19090990
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate].

Youdim MB, Weinstock M.

Cell Mol Neurobiol. 2001 Dec;21(6):555-73. Review.

PMID:
12043833
[PubMed - indexed for MEDLINE]
19.

Redox-active metals, oxidative stress, and Alzheimer's disease pathology.

Huang X, Moir RD, Tanzi RE, Bush AI, Rogers JT.

Ann N Y Acad Sci. 2004 Mar;1012:153-63. Review.

PMID:
15105262
[PubMed - indexed for MEDLINE]
20.

Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease.

Rogers JT, Bush AI, Cho HH, Smith DH, Thomson AM, Friedlich AL, Lahiri DK, Leedman PJ, Huang X, Cahill CM.

Biochem Soc Trans. 2008 Dec;36(Pt 6):1282-7. doi: 10.1042/BST0361282. Review.

PMID:
19021541
[PubMed - indexed for MEDLINE]
Free PMC Article

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