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Items: 1 to 20 of 61

1.

5-Lipoxygenase: regulation of expression and enzyme activity.

Rådmark O, Werz O, Steinhilber D, Samuelsson B.

Trends Biochem Sci. 2007 Jul;32(7):332-41. Epub 2007 Jun 18. Review.

PMID:
17576065
2.

Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis.

Rådmark O, Samuelsson B.

Biochem Biophys Res Commun. 2010 May 21;396(1):105-10. doi: 10.1016/j.bbrc.2010.02.173. Review.

PMID:
20494120
3.

5-Lipoxygenase: enzyme expression and regulation of activity.

Steinhilber D.

Pharm Acta Helv. 1994 Jul;69(1):3-14. Review.

PMID:
7938075
4.

Pharmacogenetics of the 5-lipoxygenase pathway in asthma.

Silverman E, In KH, Yandava C, Drazen JM.

Clin Exp Allergy. 1998 Nov;28 Suppl 5:164-70; discussion 171-3. Review.

PMID:
9988463
5.

5-Lipoxygenase: a target for antiinflammatory drugs revisited.

Steinhilber D.

Curr Med Chem. 1999 Jan;6(1):71-85. Review.

PMID:
9873115
6.

Nuclear import of arachidonate 5-lipoxygenase.

Brock TG, Healy AM.

Arch Immunol Ther Exp (Warsz). 2000;48(6):481-6. Review.

PMID:
11197602
7.

5-lipoxygenase mRNA and protein isoforms.

Ochs MJ, Suess B, Steinhilber D.

Basic Clin Pharmacol Toxicol. 2014 Jan;114(1):78-82. doi: 10.1111/bcpt.12115. Epub 2013 Sep 10. Review.

8.

5-lipoxygenase: cellular biology and molecular pharmacology.

Werz O.

Curr Drug Targets Inflamm Allergy. 2002 Mar;1(1):23-44. Review.

PMID:
14561204
9.

Development of 5-lipoxygenase inhibitors--lessons from cellular enzyme regulation.

Werz O, Steinhilber D.

Biochem Pharmacol. 2005 Aug 1;70(3):327-33. Review.

PMID:
15907806
10.

The biology of 5-lipoxygenase: function, structure, and regulatory mechanisms.

Silverman ES, Drazen JM.

Proc Assoc Am Physicians. 1999 Nov-Dec;111(6):525-36. Review.

PMID:
10591081
11.

Structural organization of the regulatory domain of human 5-lipoxygenase.

Allard JB, Brock TG.

Curr Protein Pept Sci. 2005 Apr;6(2):125-31. Review.

PMID:
15853649
12.

5-lipoxygenase and FLAP.

Peters-Golden M, Brock TG.

Prostaglandins Leukot Essent Fatty Acids. 2003 Aug-Sep;69(2-3):99-109. Review.

PMID:
12895592
13.

5-lipoxygenase: regulation and possible involvement in atherosclerosis.

Rådmark O, Samuelsson B.

Prostaglandins Other Lipid Mediat. 2007 May;83(3):162-74. Epub 2007 Jan 25. Review.

PMID:
17481551
14.

[Inhibitors of 5-lipoxygenase].

Gápovský M, Remko M.

Ceska Slov Farm. 2002 Mar;51(2):55-62. Review. Slovak.

PMID:
11928277
15.

Involvement of leukotriene pathway in the pathogenesis of ischemia-reperfusion injury and septic and non-septic shock.

Rossi A, Cuzzocrea S, Sautebin L.

Curr Vasc Pharmacol. 2009 Apr;7(2):185-97. Review.

PMID:
19356002
16.

On the biosynthesis and biological role of eoxins and 15-lipoxygenase-1 in airway inflammation and Hodgkin lymphoma.

Claesson HE.

Prostaglandins Other Lipid Mediat. 2009 Sep;89(3-4):120-5. doi: 10.1016/j.prostaglandins.2008.12.003. Epub 2008 Dec 14. Review.

PMID:
19130894
17.

Therapeutic options for 5-lipoxygenase inhibitors.

Werz O, Steinhilber D.

Pharmacol Ther. 2006 Dec;112(3):701-18. Epub 2006 Jul 11. Review.

PMID:
16837050
18.

Extending the understanding of leukotrienes in asthma.

Coffey M, Peters-Golden M.

Curr Opin Allergy Clin Immunol. 2003 Feb;3(1):57-63. Review.

PMID:
12582316
19.

The 5-lipoxygenase/leukotriene pathway in preclinical models of cardiovascular disease.

Poeckel D, Funk CD.

Cardiovasc Res. 2010 May 1;86(2):243-53. doi: 10.1093/cvr/cvq016. Epub 2010 Jan 21. Review.

20.

Inhibitors of the 5-lipoxygenase pathway in atherosclerosis.

Bäck M.

Curr Pharm Des. 2009;15(27):3116-32. Review.

PMID:
19754386
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