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Results: 1 to 20 of 107

1.

The role of the BRCA1 tumor suppressor in DNA double-strand break repair.

Zhang J, Powell SN.

Mol Cancer Res. 2005 Oct;3(10):531-9. Review.

PMID:
16254187
[PubMed - indexed for MEDLINE]
Free Article
2.

Therapeutic exploitation of tumor cell defects in homologous recombination.

Powell SN, Kachnic LA.

Anticancer Agents Med Chem. 2008 May;8(4):448-60. Review.

PMID:
18473729
[PubMed - indexed for MEDLINE]
3.

Good timing in the cell cycle for precise DNA repair by BRCA1.

Durant ST, Nickoloff JA.

Cell Cycle. 2005 Sep;4(9):1216-22. Epub 2005 Sep 13. Review.

PMID:
16103751
[PubMed - indexed for MEDLINE]
Free Article
4.

Human syndromes with genomic instability and multiprotein machines that repair DNA double-strand breaks.

De la Torre C, Pincheira J, López-Sáez JF.

Histol Histopathol. 2003 Jan;18(1):225-43. Review.

PMID:
12507302
[PubMed - indexed for MEDLINE]
5.

The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair.

Starita LM, Parvin JD.

Curr Opin Cell Biol. 2003 Jun;15(3):345-50. Review.

PMID:
12787778
[PubMed - indexed for MEDLINE]
6.

Homologous repair of DNA damage and tumorigenesis: the BRCA connection.

Jasin M.

Oncogene. 2002 Dec 16;21(58):8981-93. Review.

PMID:
12483514
[PubMed - indexed for MEDLINE]
Free Article
7.

Role played by BRCA1 in regulating the cellular response to stress.

Gilmore PM, Quinn JE, Mullan PB, Andrews HN, McCabe N, Carty M, Kennedy RD, Harkin DP.

Biochem Soc Trans. 2003 Feb;31(Pt 1):257-62. Review.

PMID:
12546697
[PubMed - indexed for MEDLINE]
8.

BRCA1 gene in breast cancer.

Rosen EM, Fan S, Pestell RG, Goldberg ID.

J Cell Physiol. 2003 Jul;196(1):19-41. Review.

PMID:
12767038
[PubMed - indexed for MEDLINE]
9.

BRCA1 role in the mitigation of radiotoxicity and chromosomal instability through repair of clustered DNA lesions.

Hair JM, Terzoudi GI, Hatzi VI, Lehockey KA, Srivastava D, Wang W, Pantelias GE, Georgakilas AG.

Chem Biol Interact. 2010 Nov 5;188(2):350-8. doi: 10.1016/j.cbi.2010.03.046. Epub 2010 Apr 4. Review.

PMID:
20371364
[PubMed - indexed for MEDLINE]
10.

Caretaker Brca1: keeping the genome in the straight and narrow.

Yu V.

Breast Cancer Res. 2000;2(2):82-5. Epub 2000 Feb 7. Review.

PMID:
11250695
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The relationship between the roles of BRCA genes in DNA repair and cancer predisposition.

Tutt A, Ashworth A.

Trends Mol Med. 2002 Dec;8(12):571-6. Review.

PMID:
12470990
[PubMed - indexed for MEDLINE]
12.

The role of BRCA1 in non-homologous end-joining.

Bau DT, Mau YC, Shen CY.

Cancer Lett. 2006 Aug 18;240(1):1-8. Epub 2005 Sep 19. Review.

PMID:
16171943
[PubMed - indexed for MEDLINE]
13.

BRCA1 16 years later: DNA damage-induced BRCA1 shuttling.

Yang ES, Xia F.

FEBS J. 2010 Aug;277(15):3079-85. doi: 10.1111/j.1742-4658.2010.07734.x. Epub 2010 Jul 1. Review.

PMID:
20608971
[PubMed - indexed for MEDLINE]
14.

BRCA1 regulation of transcription.

Rosen EM, Fan S, Ma Y.

Cancer Lett. 2006 May 18;236(2):175-85. Epub 2005 Jun 21. Review.

PMID:
15975711
[PubMed - indexed for MEDLINE]
15.

The DNA double-strand break response pathway: becoming more BRCAish than ever.

Ting NS, Lee WH.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):935-44. Review.

PMID:
15279779
[PubMed - indexed for MEDLINE]
16.

BRCA1 involvement in toxicological responses and human cancer etiology.

Georgakilas AG, Aziz K, Ziech D, Georgakila S, Panayiotidis MI.

Toxicol Lett. 2009 Jul 24;188(2):77-83. doi: 10.1016/j.toxlet.2009.04.006. Epub 2009 Apr 16. Review.

PMID:
19375487
[PubMed - indexed for MEDLINE]
17.

Targeting the DNA repair defect of BRCA tumours.

Turner N, Tutt A, Ashworth A.

Curr Opin Pharmacol. 2005 Aug;5(4):388-93. Review.

PMID:
15955736
[PubMed - indexed for MEDLINE]
18.

Roles of BRCA1 in DNA damage repair: a link between development and cancer.

Deng CX, Wang RH.

Hum Mol Genet. 2003 Apr 1;12 Spec No 1:R113-23. Review.

PMID:
12668603
[PubMed - indexed for MEDLINE]
Free Article
19.

BRCA gene structure and function in tumor suppression: a repair-centric perspective.

Murphy CG, Moynahan ME.

Cancer J. 2010 Jan-Feb;16(1):39-47. doi: 10.1097/PPO.0b013e3181cf0204. Review.

PMID:
20164689
[PubMed - indexed for MEDLINE]
20.

Analysis of DNA double-strand break repair pathways in mice.

Brugmans L, Kanaar R, Essers J.

Mutat Res. 2007 Jan 3;614(1-2):95-108. Epub 2006 Jun 23. Review.

PMID:
16797606
[PubMed - indexed for MEDLINE]

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