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Results: 1 to 20 of 49

1.

Translation of ischemic preconditioning to the patient: prolyl hydroxylase inhibition and hypoxia inducible factor-1 as novel targets for stroke therapy.

Ratan RR, Siddiq A, Aminova L, Lange PS, Langley B, Ayoub I, Gensert J, Chavez J.

Stroke. 2004 Nov;35(11 Suppl 1):2687-9. Epub 2004 Oct 7. Review.

PMID:
15472113
[PubMed - indexed for MEDLINE]
Free Article
2.

Prolyl hydroxylase domain inhibitors: a route to HIF activation and neuroprotection.

Harten SK, Ashcroft M, Maxwell PH.

Antioxid Redox Signal. 2010 Apr;12(4):459-80. doi: 10.1089/ars.2009.2870. Review.

PMID:
19737089
[PubMed - indexed for MEDLINE]
3.

The prolyl hydroxylase enzymes that act as oxygen sensors regulating destruction of hypoxia-inducible factor alpha.

Willam C, Nicholls LG, Ratcliffe PJ, Pugh CW, Maxwell PH.

Adv Enzyme Regul. 2004;44:75-92. Review. No abstract available.

PMID:
15581484
[PubMed - indexed for MEDLINE]
4.
5.

Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology.

Semenza GL.

Trends Mol Med. 2001 Aug;7(8):345-50. Review.

PMID:
11516994
[PubMed - indexed for MEDLINE]
6.

Organ protection by hypoxia and hypoxia-inducible factors.

Bernhardt WM, Warnecke C, Willam C, Tanaka T, Wiesener MS, Eckardt KU.

Methods Enzymol. 2007;435:221-45. Review.

PMID:
17998057
[PubMed - indexed for MEDLINE]
7.

Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics?

Karuppagounder SS, Ratan RR.

J Cereb Blood Flow Metab. 2012 Jul;32(7):1347-61. doi: 10.1038/jcbfm.2012.28. Epub 2012 Mar 14. Review.

PMID:
22415525
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Hypoxia, HIF-1, and the pathophysiology of common human diseases.

Semenza GL, Agani F, Feldser D, Iyer N, Kotch L, Laughner E, Yu A.

Adv Exp Med Biol. 2000;475:123-30. Review.

PMID:
10849654
[PubMed - indexed for MEDLINE]
9.

Hypoxia-inducible factor 1: control of oxygen homeostasis in health and disease.

Semenza GL.

Pediatr Res. 2001 May;49(5):614-7. Review.

PMID:
11328942
[PubMed - indexed for MEDLINE]
10.

Hypoxia-inducible factor 1 in lower limb ischemia.

Ho TK, Abraham DJ, Black CM, Baker DM.

Vascular. 2006 Nov-Dec;14(6):321-7. Review.

PMID:
17150152
[PubMed - indexed for MEDLINE]
11.

HIF-1alpha and p53 promote hypoxia-induced delayed neuronal death in models of CNS ischemia.

Halterman MW, Federoff HJ.

Exp Neurol. 1999 Sep;159(1):65-72. Review.

PMID:
10486175
[PubMed - indexed for MEDLINE]
12.

Review: hypoxia-inducible factor-1 (HIF-1): a novel transcription factor in immune reactions.

Hellwig-Bürgel T, Stiehl DP, Wagner AE, Metzen E, Jelkmann W.

J Interferon Cytokine Res. 2005 Jun;25(6):297-310. Review.

PMID:
15957953
[PubMed - indexed for MEDLINE]
13.

[Hypoxic preconditioning: role of transcription factor HIF-1alpha].

Belaïdi E, Béguin PC, Ribuot C, Godin-Ribuot D.

Ann Cardiol Angeiol (Paris). 2006 Apr;55(2):70-3. Review. French.

PMID:
16708989
[PubMed - indexed for MEDLINE]
14.

Hydroxylation of hypoxia-inducible transcription factors and chemical compounds targeting the HIF-alpha hydroxylases.

Bruegge K, Jelkmann W, Metzen E.

Curr Med Chem. 2007;14(17):1853-62. Review.

PMID:
17627521
[PubMed - indexed for MEDLINE]
15.

Erythropoietin--a novel concept for neuroprotection.

Sirén AL, Ehrenreich H.

Eur Arch Psychiatry Clin Neurosci. 2001 Aug;251(4):179-84. Review.

PMID:
11697582
[PubMed - indexed for MEDLINE]
16.

Harnessing hypoxic adaptation to prevent, treat, and repair stroke.

Ratan RR, Siddiq A, Smirnova N, Karpisheva K, Haskew-Layton R, McConoughey S, Langley B, Estevez A, Huerta PT, Volpe B, Roy S, Sen CK, Gazaryan I, Cho S, Fink M, LaManna J.

J Mol Med (Berl). 2007 Dec;85(12):1331-8. Epub 2007 Nov 28. Review.

PMID:
18043901
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Novel drugs and the response to hypoxia: HIF stabilizers and prolyl hydroxylase.

Nangaku M, Kojima I, Tanaka T, Ohse T, Kato H, Fujita T.

Recent Pat Cardiovasc Drug Discov. 2006 Jun;1(2):129-39. Review.

PMID:
18221080
[PubMed - indexed for MEDLINE]
18.

Molecular biology of erythropoietin.

Jelkmann W.

Intern Med. 2004 Aug;43(8):649-59. Review.

PMID:
15468961
[PubMed - indexed for MEDLINE]
Free Article
19.

Hypoxia-inducible factor 1 (HIF-1) in cancer.

Quintero M, Mackenzie N, Brennan PA.

Eur J Surg Oncol. 2004 Jun;30(5):465-8. Review.

PMID:
15135470
[PubMed - indexed for MEDLINE]
20.

Hypoxia-inducible factors and kidney vascular development.

Freeburg PB, Abrahamson DR.

J Am Soc Nephrol. 2003 Nov;14(11):2723-30. Review.

PMID:
14569081
[PubMed - indexed for MEDLINE]
Free Article

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