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Items: 1 to 20 of 33

1.

Structure and function of the glucocorticoid receptor ligand binding domain.

Bledsoe RK, Stewart EL, Pearce KH.

Vitam Horm. 2004;68:49-91. Review.

PMID:
15193451
2.

Gene regulation by the glucocorticoid receptor: structure:function relationship.

Kumar R, Thompson EB.

J Steroid Biochem Mol Biol. 2005 Apr;94(5):383-94. Epub 2005 Apr 22. Review.

PMID:
15876404
3.
4.

Crystallization of the human glucocorticoid receptor ligand binding domain: a step towards selective glucocorticoids.

Necela BM, Cidlowski JA.

Trends Pharmacol Sci. 2003 Feb;24(2):58-61. Review.

PMID:
12559765
5.

Rational ligand-based virtual screening and structure-activity relationship studies in the ligand-binding domain of the glucocorticoid receptor-α.

Onnis V, Kinsella GK, Carta G, Fayne D, Lloyd DG.

Future Med Chem. 2009 Jun;1(3):483-99. doi: 10.4155/fmc.09.39. Review.

PMID:
21426128
6.

Sequence variants of the ligand-binding domain of the glucocorticoid receptor gene and their functional consequences on the three-dimensional protein structure.

Likó I, Igaz P, Patócs A, Tóth S, Pázmány T, Tóth M, Rácz K.

Curr Med Chem. 2004 Dec;11(24):3229-37. Review.

PMID:
15579010
7.

Mineralocorticoid receptor binding, structure and function.

Rogerson FM, Brennan FE, Fuller PJ.

Mol Cell Endocrinol. 2004 Mar 31;217(1-2):203-12. Review.

PMID:
15134819
8.

Selective glucocorticoid receptor agonists (SEGRAs): novel ligands with an improved therapeutic index.

Schäcke H, Berger M, Rehwinkel H, Asadullah K.

Mol Cell Endocrinol. 2007 Sep 15;275(1-2):109-17. Epub 2007 May 31. Review.

PMID:
17630119
9.

Cortisol resistance in conditions such as asthma and the involvement of 11beta-HSD-2: a hypothesis.

Pretorius E, Wallner B, Marx J.

Horm Metab Res. 2006 Jun;38(6):368-76. Review.

PMID:
16823718
10.
11.

Selective transrepression versus transactivation mechanisms by glucocorticoid receptor modulators in stress and immune systems.

De Bosscher K, Van Craenenbroeck K, Meijer OC, Haegeman G.

Eur J Pharmacol. 2008 Apr 7;583(2-3):290-302. doi: 10.1016/j.ejphar.2007.11.076. Epub 2008 Jan 31. Review.

PMID:
18289525
13.

Structural analysis of the GR ligand-binding domain.

Egner U.

Ernst Schering Res Found Workshop. 2002;(40):341-56. Review. No abstract available.

PMID:
12355725
14.

Intracellular glucocorticoid signaling: a formerly simple system turns stochastic.

Chrousos GP, Kino T.

Sci STKE. 2005 Oct 4;2005(304):pe48. Review.

PMID:
16204701
15.

Negative glucocorticoid receptor response elements and their role in glucocorticoid action.

Dostert A, Heinzel T.

Curr Pharm Des. 2004;10(23):2807-16. Review.

PMID:
15379669
16.

Mechanisms generating diversity in glucocorticoid receptor signaling.

Revollo JR, Cidlowski JA.

Ann N Y Acad Sci. 2009 Oct;1179:167-78. doi: 10.1111/j.1749-6632.2009.04986.x. Review.

PMID:
19906239
17.

The physiology of human glucocorticoid receptor beta (hGRbeta) and glucocorticoid resistance.

Lewis-Tuffin LJ, Cidlowski JA.

Ann N Y Acad Sci. 2006 Jun;1069:1-9. Review.

PMID:
16855130
18.

Drug insight: selective agonists and antagonists of the glucocorticoid receptor.

McMaster A, Ray DW.

Nat Clin Pract Endocrinol Metab. 2008 Feb;4(2):91-101. doi: 10.1038/ncpendmet0745. Review.

PMID:
18212811
19.

Functional probing of glucocorticoid receptor structure.

Carlstedt-Duke J, Gustafsson JA.

J Steroid Biochem. 1988 Oct;31(4B):593-7. Review.

PMID:
3059058
20.

Structural insights into ligand-induced activation of the insulin receptor.

Ward C, Lawrence M, Streltsov V, Garrett T, McKern N, Lou MZ, Lovrecz G, Adams T.

Acta Physiol (Oxf). 2008 Jan;192(1):3-9. doi: 10.1111/j.1748-1716.2007.01781.x. Review.

PMID:
18171424
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