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Psychopharmacol Commun. 1975;1(4):445-54.

A sensitive GLC method for the determination of imipramine and desmethylimipramine using a nitrogen detector.

Abstract

A sensitive method for determination of imipramine and desmethylimipramine using a GLC system fitted with a new nitrogen detector is described. The lower limit of sensitivity is less than 1 ng/ml with a lower limit enabling quantitation with acceptable precision of 3-5 ng/ml. Data from 20 control subjects given a single oral dose of imipramine are shown.

PMID:
1224013
[PubMed - indexed for MEDLINE]
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