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Results: 1 to 20 of 31

1.

p53 Modulates the exonuclease activity of Werner syndrome protein.

Brosh RM Jr, Karmakar P, Sommers JA, Yang Q, Wang XW, Spillare EA, Harris CC, Bohr VA.

J Biol Chem. 2001 Sep 14;276(37):35093-102. Epub 2001 Jun 26.

PMID:
11427532
[PubMed - indexed for MEDLINE]
Free Article
2.

Unwinding the molecular basis of the Werner syndrome.

Shen J, Loeb LA.

Mech Ageing Dev. 2001 Jul 15;122(9):921-44. Review.

PMID:
11348659
[PubMed - indexed for MEDLINE]
3.

Werner syndrome protein: biochemical properties and functional interactions.

Bohr VA, Cooper M, Orren D, Machwe A, Piotrowski J, Sommers J, Karmakar P, Brosh R.

Exp Gerontol. 2000 Sep;35(6-7):695-702. Review.

PMID:
11053659
[PubMed - indexed for MEDLINE]
4.

The Werner syndrome protein: an update.

Oshima J.

Bioessays. 2000 Oct;22(10):894-901. Review.

PMID:
10984715
[PubMed - indexed for MEDLINE]
5.

The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases.

Shen JC, Loeb LA.

Trends Genet. 2000 May;16(5):213-20. Review.

PMID:
10782115
[PubMed - indexed for MEDLINE]
6.

The Werner syndrome helicase-nuclease--one protein, many mysteries.

Fry M.

Sci Aging Knowledge Environ. 2002 Apr 3;2002(13):re2. Review.

PMID:
14602980
[PubMed - indexed for MEDLINE]
7.

Role of Werner syndrome gene product helicase in carcinogenesis and in resistance to genotoxins by cancer cells.

Futami K, Ishikawa Y, Goto M, Furuichi Y, Sugimoto M.

Cancer Sci. 2008 May;99(5):843-8. doi: 10.1111/j.1349-7006.2008.00778.x. Epub 2008 Feb 26. Review.

PMID:
18312465
[PubMed - indexed for MEDLINE]
8.

Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

Opresko PL, Cheng WH, von Kobbe C, Harrigan JA, Bohr VA.

Carcinogenesis. 2003 May;24(5):791-802. Review.

PMID:
12771022
[PubMed - indexed for MEDLINE]
Free Article
9.

The Werner syndrome. A model for the study of human aging.

Nehlin JO, Skovgaard GL, Bohr VA.

Ann N Y Acad Sci. 2000 Jun;908:167-79. Review.

PMID:
10911957
[PubMed - indexed for MEDLINE]
10.

Roles of the Werner syndrome protein in pathways required for maintenance of genome stability.

Brosh RM Jr, Bohr VA.

Exp Gerontol. 2002 Apr;37(4):491-506. Review.

PMID:
11830352
[PubMed - indexed for MEDLINE]
11.

Current advances in unraveling the function of the Werner syndrome protein.

Ozgenc A, Loeb LA.

Mutat Res. 2005 Sep 4;577(1-2):237-51. Review.

PMID:
15946710
[PubMed - indexed for MEDLINE]
12.

Pathways and functions of the Werner syndrome protein.

Lee JW, Harrigan J, Opresko PL, Bohr VA.

Mech Ageing Dev. 2005 Jan;126(1):79-86. Review.

PMID:
15610765
[PubMed - indexed for MEDLINE]
13.

Werner syndrome protein: functions in the response to DNA damage and replication stress in S-phase.

Cheng WH, Muftuoglu M, Bohr VA.

Exp Gerontol. 2007 Sep;42(9):871-8. Epub 2007 May 10. Review.

PMID:
17587522
[PubMed - indexed for MEDLINE]
14.

Werner syndrome: genetic and molecular basis of a premature aging disorder.

Lebel M.

Cell Mol Life Sci. 2001 Jun;58(7):857-67. Review.

PMID:
11497235
[PubMed - indexed for MEDLINE]
15.

The role of WRN in DNA repair is affected by post-translational modifications.

Kusumoto R, Muftuoglu M, Bohr VA.

Mech Ageing Dev. 2007 Jan;128(1):50-7. Epub 2006 Nov 20. Review.

PMID:
17116323
[PubMed - indexed for MEDLINE]
16.

Werner syndrome: molecular insights into the relationships between defective DNA metabolism, genomic instability, cancer and aging.

Orren DK.

Front Biosci. 2006 Sep 1;11:2657-71. Review.

PMID:
16720342
[PubMed - indexed for MEDLINE]
17.

Deficient DNA repair in the human progeroid disorder, Werner syndrome.

Bohr VA.

Mutat Res. 2005 Sep 4;577(1-2):252-9. Review.

PMID:
15916783
[PubMed - indexed for MEDLINE]
18.

The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis.

Muftuoglu M, Oshima J, von Kobbe C, Cheng WH, Leistritz DF, Bohr VA.

Hum Genet. 2008 Nov;124(4):369-77. doi: 10.1007/s00439-008-0562-0. Epub 2008 Sep 23. Review.

PMID:
18810497
[PubMed - indexed for MEDLINE]
19.

WRN mutations in Werner syndrome.

Moser MJ, Oshima J, Monnat RJ Jr.

Hum Mutat. 1999;13(4):271-9. Review. Erratum in: Hum Mutat 1999;14(1):84-5.

PMID:
10220139
[PubMed - indexed for MEDLINE]
20.

[Functional analysis of yeast homologue gene associated with human DNA helicase causative syndromes].

Miyajima A.

Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku. 2002;(120):53-74. Review. Japanese.

PMID:
12638184
[PubMed - indexed for MEDLINE]

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