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Results: 14

1.

A new aspartyl protease on 21q22.3, BACE2, is highly similar to Alzheimer's amyloid precursor protein beta-secretase.

Solans A, Estivill X, de La Luna S.

Cytogenet Cell Genet. 2000;89(3-4):177-84.

PMID:
10965118
[PubMed - indexed for MEDLINE]
2.

The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.

Stockley JH, O'Neill C.

Biochem Soc Trans. 2007 Jun;35(Pt 3):574-6. Review.

PMID:
17511655
[PubMed - indexed for MEDLINE]
3.

The beta-secretase, BACE: a prime drug target for Alzheimer's disease.

Vassar R.

J Mol Neurosci. 2001 Oct;17(2):157-70. Review.

PMID:
11816789
[PubMed - indexed for MEDLINE]
4.

BACE1: the beta-secretase enzyme in Alzheimer's disease.

Vassar R.

J Mol Neurosci. 2004;23(1-2):105-14. Review.

PMID:
15126696
[PubMed - indexed for MEDLINE]
5.

Beta-secretase (BACE) as a drug target for Alzheimer's disease.

Vassar R.

Adv Drug Deliv Rev. 2002 Dec 7;54(12):1589-602. Review.

PMID:
12453676
[PubMed - indexed for MEDLINE]
6.

Targeting BACE with small inhibitory nucleic acids - a future for Alzheimer's disease therapy?

Nawrot B.

Acta Biochim Pol. 2004;51(2):431-44. Review.

PMID:
15218540
[PubMed - indexed for MEDLINE]
Free Article
7.

Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease.

Johnston JA, Liu WW, Todd SA, Coulson DT, Murphy S, Irvine GB, Passmore AP.

Biochem Soc Trans. 2005 Nov;33(Pt 5):1096-100. Review.

PMID:
16246054
[PubMed - indexed for MEDLINE]
8.

The amyloid peptide precursor in Alzheimer's disease.

Octave JN.

Acta Neurol Belg. 1995 Dec;95(4):197-209. Review.

PMID:
8553793
[PubMed - indexed for MEDLINE]
9.

Regulation of APP cleavage by alpha-, beta- and gamma-secretases.

Nunan J, Small DH.

FEBS Lett. 2000 Oct 13;483(1):6-10. Review.

PMID:
11033346
[PubMed - indexed for MEDLINE]
Free Article
10.

Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.

Steiner H, Capell A, Leimer U, Haass C.

Eur Arch Psychiatry Clin Neurosci. 1999;249(6):266-70. Review.

PMID:
10653281
[PubMed - indexed for MEDLINE]
11.

Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease.

Huse JT, Doms RW.

Mol Neurobiol. 2000 Aug-Dec;22(1-3):81-98. Review.

PMID:
11414282
[PubMed - indexed for MEDLINE]
12.

Uncovering gamma-secretase.

Steiner H.

Curr Alzheimer Res. 2004 Aug;1(3):175-81. Review.

PMID:
15975065
[PubMed - indexed for MEDLINE]
13.

Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome.

Beyreuther K, Pollwein P, Multhaup G, Mönning U, König G, Dyrks T, Schubert W, Masters CL.

Ann N Y Acad Sci. 1993 Sep 24;695:91-102. Review.

PMID:
8239320
[PubMed - indexed for MEDLINE]
14.

BACE2 as a new diabetes target: a patent review (2010 - 2012).

Southan C.

Expert Opin Ther Pat. 2013 May;23(5):649-63. doi: 10.1517/13543776.2013.780032. Epub 2013 Mar 18. Review.

PMID:
23506624
[PubMed - indexed for MEDLINE]

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