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Items: 1 to 20 of 200

2.

Chemical substructures in drug discovery.

Merlot C, Domine D, Cleva C, Church DJ.

Drug Discov Today. 2003 Jul 1;8(13):594-602. Review.

PMID:
12850335
3.

Current parallel chemistry principles and practice: application to the discovery of biologically active molecules.

Edwards PJ.

Curr Opin Drug Discov Devel. 2009 Nov;12(6):899-914. Review.

PMID:
19894197
4.

Design of small molecule libraries for NMR screening and other applications in drug discovery.

Jacoby E, Davies J, Blommers MJ.

Curr Top Med Chem. 2003;3(1):11-23. Review.

PMID:
12570776
5.

Diversity in medicinal chemistry space.

Gorse AD.

Curr Top Med Chem. 2006;6(1):3-18. Review.

PMID:
16454754
6.

Combinatorial approaches in anticancer drug discovery: recent advances in design and synthesis.

Bhattacharyya S.

Curr Med Chem. 2001 Oct;8(12):1383-404. Review.

PMID:
11562273
7.

Chemistry challenges in lead optimization: silicon isosteres in drug discovery.

Showell GA, Mills JS.

Drug Discov Today. 2003 Jun 15;8(12):551-6. Review.

PMID:
12821303
8.

Strategies for designing GPCR-focused libraries and screening sets.

Jimonet P, Jäger R.

Curr Opin Drug Discov Devel. 2004 May;7(3):325-33. Review.

PMID:
15216936
9.

Drug discovery in the kinase inhibitory field using the Nested Chemical Library technology.

Kéri G, Székelyhidi Z, Bánhegyi P, Varga Z, Hegymegi-Barakonyi B, Szántai-Kis C, Hafenbradl D, Klebl B, Muller G, Ullrich A, Erös D, Horváth Z, Greff Z, Marosfalvi J, Pató J, Szabadkai I, Szilágyi I, Szegedi Z, Varga I, Wáczek F, Orfi L.

Assay Drug Dev Technol. 2005 Oct;3(5):543-51. Review.

PMID:
16305311
10.

High impact technologies for natural products screening.

Koehn FE.

Prog Drug Res. 2008;65:175, 177-210. Review.

PMID:
18084916
11.

Chemoproteomics as a basis for post-genomic drug discovery.

Beroza P, Villar HO, Wick MM, Martin GR.

Drug Discov Today. 2002 Aug 1;7(15):807-14. Review.

PMID:
12546968
12.

Selection criteria for drug-like compounds.

Muegge I.

Med Res Rev. 2003 May;23(3):302-21. Review.

PMID:
12647312
13.

Pharmacophore features of potential drugs.

Muegge I.

Chemistry. 2002 May 3;8(9):1976-81. Review.

PMID:
11981881
14.

Importance of molecular computer modeling in anticancer drug development.

Geromichalos GD.

J BUON. 2007 Sep;12 Suppl 1:S101-18. Review.

PMID:
17935268
15.

[Development of antituberculous drugs: current status and future prospects].

Tomioka H, Namba K.

Kekkaku. 2006 Dec;81(12):753-74. Review. Japanese.

PMID:
17240921
16.

Pursuing the leadlikeness concept in pharmaceutical research.

Hann MM, Oprea TI.

Curr Opin Chem Biol. 2004 Jun;8(3):255-63. Review.

PMID:
15183323
17.

Expanding the medicinally relevant chemical space with compound libraries.

López-Vallejo F, Giulianotti MA, Houghten RA, Medina-Franco JL.

Drug Discov Today. 2012 Jul;17(13-14):718-26. doi: 10.1016/j.drudis.2012.04.001. Epub 2012 Apr 10. Review.

PMID:
22515962
18.

The application of multi-component reactions in drug discovery.

Weber L.

Curr Med Chem. 2002 Dec;9(23):2085-93. Review.

PMID:
12470248
19.

Combinatorial drug discovery: which methods will produce the greatest value?

Ecker DJ, Crooke ST.

Biotechnology (N Y). 1995 Apr;13(4):351-60. Review.

PMID:
9634776
20.

Combinatorial chemistry as a tool for drug discovery.

Floyd CD, Leblanc C, Whittaker M.

Prog Med Chem. 1999;36:91-168. Review.

PMID:
10818672
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