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Items: 16

1.

Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells.

Persad S, Attwell S, Gray V, Delcommenne M, Troussard A, Sanghera J, Dedhar S.

Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3207-12.

2.

Integrin-linked kinase (ILK): a "hot" therapeutic target.

Yoganathan TN, Costello P, Chen X, Jabali M, Yan J, Leung D, Zhang Z, Yee A, Dedhar S, Sanghera J.

Biochem Pharmacol. 2000 Oct 15;60(8):1115-9. Review.

PMID:
11007949
3.

Biological role of phosphatase PTEN in cancer and tissue injury healing.

Tsugawa K, Jones MK, Sugimachi K, Sarfeh IJ, Tarnawski AS.

Front Biosci. 2002 May 1;7:e245-51. Review.

PMID:
11991859
4.

The role of integrin-linked kinase (ILK) in cancer progression.

Persad S, Dedhar S.

Cancer Metastasis Rev. 2003 Dec;22(4):375-84. Review.

PMID:
12884912
5.

Putting the rap on Akt.

Thompson JE, Thompson CB.

J Clin Oncol. 2004 Oct 15;22(20):4217-26. Review.

PMID:
15483033
6.
7.

The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network.

Mayo LD, Donner DB.

Trends Biochem Sci. 2002 Sep;27(9):462-7. Review.

PMID:
12217521
8.

Inhibition of protein kinase B/Akt. implications for cancer therapy.

Hill MM, Hemmings BA.

Pharmacol Ther. 2002 Feb-Mar;93(2-3):243-51. Review.

PMID:
12191616
9.
10.

Akt: a potential target for thyroid cancer therapy.

Kada F, Saji M, Ringel MD.

Curr Drug Targets Immune Endocr Metabol Disord. 2004 Sep;4(3):181-5. Review.

PMID:
15379721
11.

Modulation of cellular apoptotic potential: contributions to oncogenesis.

Stambolic V, Mak TW, Woodgett JR.

Oncogene. 1999 Nov 1;18(45):6094-103. Review.

12.
13.

Apoptosis in prostate cancer: progressive and therapeutic implications (Review).

Wang G, Reed E, Li QQ.

Int J Mol Med. 2004 Jul;14(1):23-34. Review.

PMID:
15202013
14.

PTEN and myotubularin: novel phosphoinositide phosphatases.

Maehama T, Taylor GS, Dixon JE.

Annu Rev Biochem. 2001;70:247-79. Review.

PMID:
11395408
15.

Akt in prostate cancer: possible role in androgen-independence.

Ghosh PM, Malik S, Bedolla R, Kreisberg JI.

Curr Drug Metab. 2003 Dec;4(6):487-96. Review.

PMID:
14683476
16.

Oncogenic ILK, tumor suppression and all that JNK.

Durbin AD, Hannigan GE, Malkin D.

Cell Cycle. 2009 Dec 15;8(24):4060-6. Epub 2009 Dec 15. Review.

PMID:
19923885
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