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Emerging role of Hpo signaling and YAP in hepatocellular carcinoma.

Valero V 3rd, Pawlik TM, Anders RA.

J Hepatocell Carcinoma. 2015 Jun 18;2:69-78. doi: 10.2147/JHC.S48505. eCollection 2015. Review.


The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and Warts.

Jahanshahi M, Hsiao K, Jenny A, Pfleger CM.

PLoS Genet. 2016 Aug 5;12(8):e1006198. doi: 10.1371/journal.pgen.1006198. eCollection 2016 Aug.


Zyxin-Siah2-Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways.

Ma B, Cheng H, Gao R, Mu C, Chen L, Wu S, Chen Q, Zhu Y.

Nat Commun. 2016 Mar 31;7:11123. doi: 10.1038/ncomms11123.


Mechanisms of Hippo pathway regulation.

Meng Z, Moroishi T, Guan KL.

Genes Dev. 2016 Jan 1;30(1):1-17. doi: 10.1101/gad.274027.115. Review.


Fat/Dachsous Signaling Promotes Drosophila Wing Growth by Regulating the Conformational State of the NDR Kinase Warts.

Vrabioiu AM, Struhl G.

Dev Cell. 2015 Dec 21;35(6):737-49. doi: 10.1016/j.devcel.2015.11.027.


Cell density regulates cancer metastasis via the Hippo pathway.

Sharif GM, Wellstein A.

Future Oncol. 2015;11(24):3253-60. doi: 10.2217/fon.15.268. Epub 2015 Nov 12.


Mammalian Sterile 20-like Kinase 1 (Mst1) Enhances the Stability of Forkhead Box P3 (Foxp3) and the Function of Regulatory T Cells by Modulating Foxp3 Acetylation.

Li J, Du X, Shi H, Deng K, Chi H, Tao W.

J Biol Chem. 2015 Dec 25;290(52):30762-70. doi: 10.1074/jbc.M115.668442. Epub 2015 Nov 3.


Lats1 suppresses centrosome overduplication by modulating the stability of Cdc25B.

Mukai S, Yabuta N, Yoshida K, Okamoto A, Miura D, Furuta Y, Abe T, Nojima H.

Sci Rep. 2015 Nov 4;5:16173. doi: 10.1038/srep16173.


Safeguarding genome stability: RASSF1A tumor suppressor regulates BRCA2 at stalled forks.

Pefani DE, O'Neill E.

Cell Cycle. 2015;14(11):1624-30. doi: 10.1080/15384101.2015.1035845.


The hippo pathway in heart development, regeneration, and diseases.

Zhou Q, Li L, Zhao B, Guan KL.

Circ Res. 2015 Apr 10;116(8):1431-47. doi: 10.1161/CIRCRESAHA.116.303311. Review.


Cell growth density modulates cancer cell vascular invasion via Hippo pathway activity and CXCR2 signaling.

Sharif GM, Schmidt MO, Yi C, Hu Z, Haddad BR, Glasgow E, Riegel AT, Wellstein A.

Oncogene. 2015 Nov 26;34(48):5879-89. doi: 10.1038/onc.2015.44. Epub 2015 Mar 16.


New genetic variants of LATS1 detected in urinary bladder and colon cancer.

Saadeldin MK, Shawer H, Mostafa A, Kassem NM, Amleh A, Siam R.

Front Genet. 2015 Jan 13;5:425. doi: 10.3389/fgene.2014.00425. eCollection 2014.


RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2.

Pefani DE, Latusek R, Pires I, Grawenda AM, Yee KS, Hamilton G, van der Weyden L, Esashi F, Hammond EM, O'Neill E.

Nat Cell Biol. 2014 Oct;16(10):962-71, 1-8. doi: 10.1038/ncb3035. Epub 2014 Sep 14. Erratum in: Nat Cell Biol. 2015 Apr;17(4):531.


Harnessing Hippo in the heart: Hippo/Yap signaling and applications to heart regeneration and rejuvenation.

Lin Z, Pu WT.

Stem Cell Res. 2014 Nov;13(3 Pt B):571-81. doi: 10.1016/j.scr.2014.04.010. Epub 2014 May 6. Review.


Salt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death.

Chen H, Huang S, Han X, Zhang J, Shan C, Tsang YH, Ma HT, Poon RY.

Cell Death Dis. 2014 Apr 17;5:e1177. doi: 10.1038/cddis.2014.154.


Defining the protein-protein interaction network of the human hippo pathway.

Wang W, Li X, Huang J, Feng L, Dolinta KG, Chen J.

Mol Cell Proteomics. 2014 Jan;13(1):119-31. doi: 10.1074/mcp.M113.030049. Epub 2013 Oct 14.


Evidence for a tumor suppressor role for the large tumor suppressor genes LATS1 and LATS2 in human cancer.

Yu T, Bachman J, Lai ZC.

Genetics. 2013 Nov;195(3):1193-6. doi: 10.1534/genetics.113.156372. Epub 2013 Sep 11.


Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling.

Hergovich A.

Cell Biosci. 2013 Aug 28;3(1):32. doi: 10.1186/2045-3701-3-32.


Underexpression of LATS1 TSG in colorectal cancer is associated with promoter hypermethylation.

Wierzbicki PM, Adrych K, Kartanowicz D, Stanislawowski M, Kowalczyk A, Godlewski J, Skwierz-Bogdanska I, Celinski K, Gach T, Kulig J, Korybalski B, Kmiec Z.

World J Gastroenterol. 2013 Jul 21;19(27):4363-73. doi: 10.3748/wjg.v19.i27.4363.


Identification of a lifespan extending mutation in the Schizosaccharomyces pombe cyclin gene clg1+ by direct selection of long-lived mutants.

Chen BR, Li Y, Eisenstatt JR, Runge KW.

PLoS One. 2013 Jul 9;8(7):e69084. doi: 10.1371/journal.pone.0069084. Print 2013.

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