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Items: 1 to 20 of 22


LASP1, a Newly Identified Melanocytic Protein with a Possible Role in Melanin Release, but Not in Melanoma Progression.

Vaman V S A, Poppe H, Houben R, Grunewald TG, Goebeler M, Butt E.

PLoS One. 2015 Jun 10;10(6):e0129219. doi: 10.1371/journal.pone.0129219. eCollection 2015.


Molecular characterization of LASP-1 expression reveals vimentin as its new partner in human hepatocellular carcinoma cells.

Salvi A, Bongarzone I, Ferrari L, Abeni E, Arici B, De Bortoli M, Scuri S, Bonini D, Grossi I, Benetti A, Baiocchi G, Portolani N, De Petro G.

Int J Oncol. 2015 May;46(5):1901-12. doi: 10.3892/ijo.2015.2923. Epub 2015 Mar 9.


An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein.

Orth MF, Cazes A, Butt E, Grunewald TG.

Oncotarget. 2015 Jan 1;6(1):26-42. Review.


LASP1 is a HIF1α target gene critical for metastasis of pancreatic cancer.

Zhao T, Ren H, Li J, Chen J, Zhang H, Xin W, Sun Y, Sun L, Yang Y, Sun J, Wang X, Gao S, Huang C, Zhang H, Yang S, Hao J.

Cancer Res. 2015 Jan 1;75(1):111-9. doi: 10.1158/0008-5472.CAN-14-2040. Epub 2014 Nov 10.


LIM and SH3 domain protein 1 (LASP-1) overexpression was associated with aggressive phenotype and poor prognosis in clear cell renal cell cancer.

Yang F, Zhou X, Du S, Zhao Y, Ren W, Deng Q, Wang F, Yuan J.

PLoS One. 2014 Jun 23;9(6):e100557. doi: 10.1371/journal.pone.0100557. eCollection 2014.


Proteomic analysis on effectors involved in BMP-2-induced osteogenic differentiation of beagle bone marrow mesenchymal stem cells.

Hu JJ, Liu YW, He MY, Jin D, Zhao H, Yu B.

Proteome Sci. 2014 Mar 1;12(1):13. doi: 10.1186/1477-5956-12-13.


Investigating lasp-2 in cell adhesion: new binding partners and roles in motility.

Bliss KT, Chu M, Jones-Weinert CM, Gregorio CC.

Mol Biol Cell. 2013 Apr;24(7):995-1006. doi: 10.1091/mbc.E12-10-0723. Epub 2013 Feb 6.


Lasp-1 regulates podosome function.

Stölting M, Wiesner C, van Vliet V, Butt E, Pavenstädt H, Linder S, Kremerskothen J.

PLoS One. 2012;7(4):e35340. doi: 10.1371/journal.pone.0035340. Epub 2012 Apr 13.


MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer.

Hudson RS, Yi M, Esposito D, Watkins SK, Hurwitz AA, Yfantis HG, Lee DH, Borin JF, Naslund MJ, Alexander RB, Dorsey TH, Stephens RM, Croce CM, Ambs S.

Nucleic Acids Res. 2012 Apr;40(8):3689-703. doi: 10.1093/nar/gkr1222. Epub 2011 Dec 30.


Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer.

Frietsch JJ, Grunewald TG, Jasper S, Kammerer U, Herterich S, Kapp M, Honig A, Butt E.

Br J Cancer. 2010 May 25;102(11):1645-53. doi: 10.1038/sj.bjc.6605685. Epub 2010 May 11.


Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.

Nakagawa H, Suzuki H, Machida S, Suzuki J, Ohashi K, Jin M, Miyamoto S, Terasaki AG.

PLoS One. 2009 Oct 23;4(10):e7530. doi: 10.1371/journal.pone.0007530.


Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models.

Wilkinson MB, Xiao G, Kumar A, LaPlant Q, Renthal W, Sikder D, Kodadek TJ, Nestler EJ.

J Neurosci. 2009 Jun 17;29(24):7820-32. doi: 10.1523/JNEUROSCI.0932-09.2009.


Lasp1 gene disruption is linked to enhanced cell migration and tumor formation.

Zhang H, Chen X, Bollag WB, Bollag RJ, Sheehan DJ, Chew CS.

Physiol Genomics. 2009 Aug 7;38(3):372-85. doi: 10.1152/physiolgenomics.00048.2009. Epub 2009 Jun 16.


Proteomic identification of LASP-1 down-regulation after RNAi urokinase silencing in human hepatocellular carcinoma cells.

Salvi A, Bongarzone I, Miccichè F, Arici B, Barlati S, De Petro G.

Neoplasia. 2009 Feb;11(2):207-19.


Ectopic expression of LIM-nebulette (LASP2) reveals roles in cell migration and spreading.

Deng XA, Norris A, Panaviene Z, Moncman CL.

Cell Motil Cytoskeleton. 2008 Oct;65(10):827-40. doi: 10.1002/cm.20304.


Global gene expression analysis identifies PDEF transcriptional networks regulating cell migration during cancer progression.

Turner DP, Findlay VJ, Kirven AD, Moussa O, Watson DK.

Mol Biol Cell. 2008 Sep;19(9):3745-57. doi: 10.1091/mbc.E08-02-0154. Epub 2008 Jun 25.


Targeted disruption of the Lasp-1 gene is linked to increases in histamine-stimulated gastric HCl secretion.

Chew CS, Chen X, Bollag RJ, Isales C, Ding KH, Zhang H.

Am J Physiol Gastrointest Liver Physiol. 2008 Jul;295(1):G37-G44. doi: 10.1152/ajpgi.90247.2008. Epub 2008 May 15.


The LIM and SH3 domain protein family: structural proteins or signal transducers or both?

Grunewald TG, Butt E.

Mol Cancer. 2008 Apr 17;7:31. doi: 10.1186/1476-4598-7-31.


Nuclear localization and cytosolic overexpression of LASP-1 correlates with tumor size and nodal-positivity of human breast carcinoma.

Grunewald TG, Kammerer U, Kapp M, Eck M, Dietl J, Butt E, Honig A.

BMC Cancer. 2007 Oct 23;7:198.


Overexpression of LASP-1 mediates migration and proliferation of human ovarian cancer cells and influences zyxin localisation.

Grunewald TG, Kammerer U, Winkler C, Schindler D, Sickmann A, Honig A, Butt E.

Br J Cancer. 2007 Jan 29;96(2):296-305. Epub 2007 Jan 9.

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