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Gα13 Stimulates the Tyrosine Phosphorylation of Ric-8A.

Yan M, Ha JH, Dhanasekaran DN.

J Mol Signal. 2015 Jul 27;10:3. doi: 10.5334/1750-2187-10-3.


BTK inhibition results in impaired CXCR4 chemokine receptor surface expression, signaling and function in chronic lymphocytic leukemia.

Chen SS, Chang BY, Chang S, Tong T, Ham S, Sherry B, Burger JA, Rai KR, Chiorazzi N.

Leukemia. 2016 Apr;30(4):833-43. doi: 10.1038/leu.2015.316. Epub 2015 Nov 9.


Quantitative Proteomics Identifies Activation of Hallmark Pathways of Cancer in Patient Melanoma.

Byrum SD, Larson SK, Avaritt NL, Moreland LE, Mackintosh SG, Cheung WL, Tackett AJ.

J Proteomics Bioinform. 2013 Mar 1;6(3):43-50.


The zinc-binding region of IL-2 inducible T cell kinase (Itk) is required for interaction with Gα13 and activation of serum response factor.

Huang W, Morales JL, Gazivoda VP, Lai J, Qi Q, August A.

Int J Biochem Cell Biol. 2013 Jun;45(6):1074-82. doi: 10.1016/j.biocel.2013.02.011. Epub 2013 Feb 27.


Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13.

Kozasa T, Hajicek N, Chow CR, Suzuki N.

J Biochem. 2011 Oct;150(4):357-69. doi: 10.1093/jb/mvr105. Epub 2011 Aug 26. Review.


Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization.

Wang L, Guo D, Xing B, Zhang JJ, Shu HB, Guo L, Huang XY.

J Biol Chem. 2011 Sep 2;286(35):31055-61. doi: 10.1074/jbc.M111.253427. Epub 2011 Jul 19.


Mitogenic Signaling by the gep Oncogene Involves the Upregulation of S-Phase Kinase-Associated Protein 2.

Radhakrishnan R, Ha JH, Dhanasekaran DN.

Genes Cancer. 2010 Oct;1(10):1033-43. doi: 10.1177/1947601910390516.


Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance.

Cohen I, Maoz M, Turm H, Grisaru-Granovsky S, Maly B, Uziely B, Weiss E, Abramovitch R, Gross E, Barzilay O, Qiu Y, Bar-Shavit R.

PLoS One. 2010 Jun 15;5(6):e11135. doi: 10.1371/journal.pone.0011135. Erratum in: PLoS One. 2010;5(12) doi: 10.1371/annotation/7ed84180-ec3d-46c0-8c10-f7b830999f8d.


The Tec family kinase Itk exists as a folded monomer in vivo.

Qi Q, August A.

J Biol Chem. 2009 Oct 23;284(43):29882-92. doi: 10.1074/jbc.M109.003129. Epub 2009 Aug 28.


Role of G12 proteins in oncogenesis and metastasis.

Juneja J, Casey PJ.

Br J Pharmacol. 2009 Sep;158(1):32-40. doi: 10.1111/j.1476-5381.2009.00180.x. Epub 2009 Apr 30. Review.


Regulation and physiological functions of G12/13-mediated signaling pathways.

Suzuki N, Hajicek N, Kozasa T.

Neurosignals. 2009;17(1):55-70. doi: 10.1159/000186690. Epub 2009 Feb 12. Review.


Chemokine signaling in cancer: one hump or two?

Rubin JB.

Semin Cancer Biol. 2009 Apr;19(2):116-22. doi: 10.1016/j.semcancer.2008.10.001. Epub 2008 Oct 17. Review.


The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.

Liao Z, Seye CI, Weisman GA, Erb L.

J Cell Sci. 2007 May 1;120(Pt 9):1654-62.


Csk mediates G-protein-coupled lysophosphatidic acid receptor-induced inhibition of membrane-bound guanylyl cyclase activity.

Madhusoodanan KS, Guo D, McGarrigle DK, Maack T, Huang XY.

Biochemistry. 2006 Mar 14;45(10):3396-403.


Inhibition of a background potassium channel by Gq protein alpha-subunits.

Chen X, Talley EM, Patel N, Gomis A, McIntire WE, Dong B, Viana F, Garrison JC, Bayliss DA.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3422-7. Epub 2006 Feb 21.


Leucine-rich repeat kinase 2: a new player with a familiar theme for Parkinson's disease pathogenesis.

Li C, Beal MF.

Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16535-6. Epub 2005 Nov 7. No abstract available.


CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca2+.

Liu Q, Walker SA, Gao D, Taylor JA, Dai YF, Arkell RS, Bootman MD, Roderick HL, Cullen PJ, Lockyer PJ.

J Cell Biol. 2005 Jul 18;170(2):183-90. Epub 2005 Jul 11.


Ligand-dependent autophosphorylation of the insulin receptor is positively regulated by Gi-proteins.

Kreuzer J, Nürnberg B, Krieger-Brauer HI.

Biochem J. 2004 Jun 15;380(Pt 3):831-6.


Identification and molecular characterization of the G alpha12-Rho guanine nucleotide exchange factor pathway in Caenorhabditis elegans.

Yau DM, Yokoyama N, Goshima Y, Siddiqui ZK, Siddiqui SS, Kozasa T.

Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14748-53. Epub 2003 Dec 1.

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