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Items: 1 to 20 of 35


Clinical efficacy of combined rituximab treatment in a woman with severe Graves' ophthalmopathy.

Liu X, Guo H, Liu J, Shi B.

Exp Ther Med. 2016 Aug;12(2):1093-1096. Epub 2016 May 19.


Effects over time of two platelet gel supernatants on growth factor, cytokine and hyaluronan concentrations in normal synovial membrane explants challenged with lipopolysaccharide.

Ríos DL, López C, Álvarez ME, Samudio IJ, Carmona JU.

BMC Musculoskelet Disord. 2015 Jun 20;16:153. doi: 10.1186/s12891-015-0605-3.


MiRNA-21 promotes fibrosis in orbital fibroblasts from thyroid-associated ophthalmopathy.

Tong BD, Xiao MY, Zeng JX, Xiong W.

Mol Vis. 2015 Mar 30;21:324-34. eCollection 2015.


Platelet-derived growth factor: a key factor in the pathogenesis of graves' ophthalmopathy and potential target for treatment.

Virakul S, van Steensel L, Dalm VA, Paridaens D, van Hagen PM, Dik WA.

Eur Thyroid J. 2014 Dec;3(4):217-26. doi: 10.1159/000367968. Epub 2014 Dec 6. Review.


TSH-receptor-expressing fibrocytes and thyroid-associated ophthalmopathy.

Smith TJ.

Nat Rev Endocrinol. 2015 Mar;11(3):171-81. doi: 10.1038/nrendo.2014.226. Epub 2015 Jan 6. Review.


PI3K/AKT pathway mediates induction of IL-1RA by TSH in fibrocytes: modulation by PTEN.

Li B, Smith TJ.

J Clin Endocrinol Metab. 2014 Sep;99(9):3363-72. doi: 10.1210/jc.2014-1257. Epub 2014 May 19.


Current concepts in the molecular pathogenesis of thyroid-associated ophthalmopathy.

Wang Y, Smith TJ.

Invest Ophthalmol Vis Sci. 2014 Mar 20;55(3):1735-48. doi: 10.1167/iovs.14-14002. Review.


Thyroid associated orbitopathy: Understanding pathophysiology.

Chaudhry IA.

Saudi J Ophthalmol. 2011 Jan;25(1):1-2. doi: 10.1016/j.sjopt.2010.11.001. Epub 2010 Nov 11. No abstract available.


Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-κB.

Gillespie EF, Raychaudhuri N, Papageorgiou KI, Atkins SJ, Lu Y, Charara LK, Mester T, Smith TJ, Douglas RS.

Invest Ophthalmol Vis Sci. 2012 Nov 21;53(12):7746-53. doi: 10.1167/iovs.12-9861.


Role of insulin-like growth factor-1 (IGF-1) pathway in the pathogenesis of Graves' orbitopathy.

Smith TJ, Hegedüs L, Douglas RS.

Best Pract Res Clin Endocrinol Metab. 2012 Jun;26(3):291-302. doi: 10.1016/j.beem.2011.10.002. Review.


Nuclear targeting of IGF-1 receptor in orbital fibroblasts from Graves' disease: apparent role of ADAM17.

Hoa N, Tsui S, Afifiyan NF, Sinha Hikim A, Li B, Douglas RS, Smith TJ.

PLoS One. 2012;7(4):e34173. doi: 10.1371/journal.pone.0034173. Epub 2012 Apr 10.


Increased expression of TSH receptor by fibrocytes in thyroid-associated ophthalmopathy leads to chemokine production.

Gillespie EF, Papageorgiou KI, Fernando R, Raychaudhuri N, Cockerham KP, Charara LK, Goncalves AC, Zhao SX, Ginter A, Lu Y, Smith TJ, Douglas RS.

J Clin Endocrinol Metab. 2012 May;97(5):E740-6. doi: 10.1210/jc.2011-2514. Epub 2012 Mar 7.


Quercetin inhibits IL-1β-induced inflammation, hyaluronan production and adipogenesis in orbital fibroblasts from Graves' orbitopathy.

Yoon JS, Lee HJ, Choi SH, Chang EJ, Lee SY, Lee EJ.

PLoS One. 2011;6(10):e26261. doi: 10.1371/journal.pone.0026261. Epub 2011 Oct 19.


Divergent Sp1 protein levels may underlie differential expression of UDP-glucose dehydrogenase by fibroblasts: role in susceptibility to orbital Graves disease.

Tsui S, Fernando R, Chen B, Smith TJ.

J Biol Chem. 2011 Jul 8;286(27):24487-99. doi: 10.1074/jbc.M111.241166. Epub 2011 May 16.


PGE2 induces IL-6 in orbital fibroblasts through EP2 receptors and increased gene promoter activity: implications to thyroid-associated ophthalmopathy.

Raychaudhuri N, Douglas RS, Smith TJ.

PLoS One. 2010 Dec 23;5(12):e15296. doi: 10.1371/journal.pone.0015296.


Immunopathogenesis of thyroid eye disease: emerging paradigms.

Naik VM, Naik MN, Goldberg RA, Smith TJ, Douglas RS.

Surv Ophthalmol. 2010 May-Jun;55(3):215-26. doi: 10.1016/j.survophthal.2009.06.009. Review.


Orbital fibroblasts from patients with thyroid-associated ophthalmopathy overexpress CD40: CD154 hyperinduces IL-6, IL-8, and MCP-1.

Hwang CJ, Afifiyan N, Sand D, Naik V, Said J, Pollock SJ, Chen B, Phipps RP, Goldberg RA, Smith TJ, Douglas RS.

Invest Ophthalmol Vis Sci. 2009 May;50(5):2262-8. doi: 10.1167/iovs.08-2328. Epub 2008 Dec 30.

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