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Histone methylation modifiers in cellular signaling pathways.

Alam H, Gu B, Lee MG.

Cell Mol Life Sci. 2015 Dec;72(23):4577-92. doi: 10.1007/s00018-015-2023-y. Epub 2015 Aug 25. Review.


Highly homologous proteins exert opposite biological activities by using different interaction interfaces.

Amir AI, van Rosmalen M, Mayer G, Lebendiker M, Danieli T, Friedler A.

Sci Rep. 2015 Jul 1;5:11629. doi: 10.1038/srep11629.


Variant TP53BP1 rs560191 G>C is associated with risk of gastric cardia adenocarcinoma in a Chinese Han population.

Zhang S, Tang W, Ding G, Liu C, Liu R, Chen S, Gu H, Yu C.

Chin J Cancer Res. 2015 Apr;27(2):156-62. doi: 10.3978/j.issn.1000-9604.2015.03.05.


KDM1 class flavin-dependent protein lysine demethylases.

Burg JM, Link JE, Morgan BS, Heller FJ, Hargrove AE, McCafferty DG.

Biopolymers. 2015 Jul;104(4):213-46. doi: 10.1002/bip.22643.


p21 rs3176352 G>C and p73 rs1801173 C>T polymorphisms are associated with an increased risk of esophageal cancer in a Chinese population.

Zheng L, Tang W, Shi Y, Chen S, Wang X, Wang L, Shao A, Ding G, Liu C, Liu R, Yin J, Gu H.

PLoS One. 2014 May 12;9(5):e96958. doi: 10.1371/journal.pone.0096958. eCollection 2014.


An unexpected journey: lysine methylation across the proteome.

Moore KE, Gozani O.

Biochim Biophys Acta. 2014 Dec;1839(12):1395-403. doi: 10.1016/j.bbagrm.2014.02.008. Epub 2014 Feb 20. Review.


Role of p53 in Cell Death and Human Cancers.

Ozaki T, Nakagawara A.

Cancers (Basel). 2011 Mar 3;3(1):994-1013. doi: 10.3390/cancers3010994.


53BP1 sensitizes breast cancer cells to 5-fluorouracil.

Li X, Kong X, Kong X, Wang Y, Yan S, Yang Q.

PLoS One. 2013 Sep 6;8(9):e74928. doi: 10.1371/journal.pone.0074928. eCollection 2013.


Genetic susceptibility to lung cancer--light at the end of the tunnel?

Marshall AL, Christiani DC.

Carcinogenesis. 2013 Mar;34(3):487-502. doi: 10.1093/carcin/bgt016. Epub 2013 Jan 24. Review.


53BP1 is a haploinsufficient tumor suppressor and protects cells from radiation response in glioma.

Squatrito M, Vanoli F, Schultz N, Jasin M, Holland EC.

Cancer Res. 2012 Oct 15;72(20):5250-60. doi: 10.1158/0008-5472.CAN-12-0045. Epub 2012 Aug 21.


The activation of DNA damage detection and repair responses in cleavage-stage rat embryos by a damaged paternal genome.

Grenier L, Robaire B, Hales BF.

Toxicol Sci. 2012 Jun;127(2):555-66. doi: 10.1093/toxsci/kfs120. Epub 2012 Mar 27.


The role of ATM and 53BP1 as predictive markers in cervical cancer.

Roossink F, Wieringa HW, Noordhuis MG, ten Hoor KA, Kok M, Slagter-Menkema L, Hollema H, de Bock GH, Pras E, de Vries EG, de Jong S, van der Zee AG, Schuuring E, Wisman GB, van Vugt MA.

Int J Cancer. 2012 Nov 1;131(9):2056-66. doi: 10.1002/ijc.27488. Epub 2012 Mar 29.


Regulation of the BRCA1 gene by an SRC3/53BP1 complex.

Corkery D, Thillainadesan G, Coughlan N, Mohan RD, Isovic M, Tini M, Torchia J.

BMC Biochem. 2011 Sep 13;12:50. doi: 10.1186/1471-2091-12-50.


Analysis of microdissected neurons by 18O mass spectrometry reveals altered protein expression in Alzheimer's disease.

Hashimoto M, Bogdanovic N, Nakagawa H, Volkmann I, Aoki M, Winblad B, Sakai J, Tjernberg LO.

J Cell Mol Med. 2012 Aug;16(8):1686-700. doi: 10.1111/j.1582-4934.2011.01441.x.


Physical and functional antagonism between tumor suppressor protein p53 and fortilin, an anti-apoptotic protein.

Chen Y, Fujita T, Zhang D, Doan H, Pinkaew D, Liu Z, Wu J, Koide Y, Chiu A, Lin CC, Chang JY, Ruan KH, Fujise K.

J Biol Chem. 2011 Sep 16;286(37):32575-85. doi: 10.1074/jbc.M110.217836. Epub 2011 Jul 27.


Requirement for DNA ligase IV during embryonic neuronal development.

Gatz SA, Ju L, Gruber R, Hoffmann E, Carr AM, Wang ZQ, Liu C, Jeggo PA.

J Neurosci. 2011 Jul 6;31(27):10088-100. doi: 10.1523/JNEUROSCI.1324-11.2011. Erratum in: J Neurosci. 2011 Sep 21;31(38):13695.


Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.

FitzGerald J, Moureau S, Drogaris P, O'Connell E, Abshiru N, Verreault A, Thibault P, Grenon M, Lowndes NF.

PLoS One. 2011 Feb 24;6(2):e14714. doi: 10.1371/journal.pone.0014714.


Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor.

Stegh AH, Brennan C, Mahoney JA, Forloney KL, Jenq HT, Luciano JP, Protopopov A, Chin L, Depinho RA.

Genes Dev. 2010 Oct 1;24(19):2194-204. doi: 10.1101/gad.1924710. Epub 2010 Sep 13.


Genetic variants in the 53BP1 gene and skin cancer risk.

He C, Nan H, Qureshi AA, Han J.

J Invest Dermatol. 2010 Dec;130(12):2850-3. doi: 10.1038/jid.2010.227. Epub 2010 Aug 5. No abstract available.


A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint.

van Vugt MA, Gardino AK, Linding R, Ostheimer GJ, Reinhardt HC, Ong SE, Tan CS, Miao H, Keezer SM, Li J, Pawson T, Lewis TA, Carr SA, Smerdon SJ, Brummelkamp TR, Yaffe MB.

PLoS Biol. 2010 Jan 26;8(1):e1000287. doi: 10.1371/journal.pbio.1000287.

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