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Items: 1 to 20 of 82


SYNGAP1: Mind the Gap.

Jeyabalan N, Clement JP.

Front Cell Neurosci. 2016 Feb 15;10:32. doi: 10.3389/fncel.2016.00032. eCollection 2016. Review.


AIDA-1 Moves out of the Postsynaptic Density Core under Excitatory Conditions.

Dosemeci A, Toy D, Reese TS, Tao-Cheng JH.

PLoS One. 2015 Sep 10;10(9):e0137216. doi: 10.1371/journal.pone.0137216. eCollection 2015.


Prioritizing the development of mouse models for childhood brain disorders.

Ogden KK, Ozkan ED, Rumbaugh G.

Neuropharmacology. 2016 Jan;100:2-16. doi: 10.1016/j.neuropharm.2015.07.029. Epub 2015 Jul 29. Review.


Wnt-related SynGAP1 is a neuroprotective factor of glutamatergic synapses against Aβ oligomers.

Codocedo JF, Montecinos-Oliva C, Inestrosa NC.

Front Cell Neurosci. 2015 Jun 15;9:227. doi: 10.3389/fncel.2015.00227. eCollection 2015.


Rapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP.

Araki Y, Zeng M, Zhang M, Huganir RL.

Neuron. 2015 Jan 7;85(1):173-89. doi: 10.1016/j.neuron.2014.12.023.


Phosphorylation of synaptic GTPase-activating protein (synGAP) by Ca2+/calmodulin-dependent protein kinase II (CaMKII) and cyclin-dependent kinase 5 (CDK5) alters the ratio of its GAP activity toward Ras and Rap GTPases.

Walkup WG 4th, Washburn L, Sweredoski MJ, Carlisle HJ, Graham RL, Hess S, Kennedy MB.

J Biol Chem. 2015 Feb 20;290(8):4908-27. doi: 10.1074/jbc.M114.614420. Epub 2014 Dec 22.


Syngap1 haploinsufficiency damages a postnatal critical period of pyramidal cell structural maturation linked to cortical circuit assembly.

Aceti M, Creson TK, Vaissiere T, Rojas C, Huang WC, Wang YX, Petralia RS, Page DT, Miller CA, Rumbaugh G.

Biol Psychiatry. 2015 May 1;77(9):805-15. doi: 10.1016/j.biopsych.2014.08.001. Epub 2014 Aug 13.


Convergent synaptic and circuit substrates underlying autism genetic risks.

McGee A, Li G, Lu Z, Qiu S.

Front Biol (Beijing). 2014 Feb 1;9(2):137-150.


Reduced cognition in Syngap1 mutants is caused by isolated damage within developing forebrain excitatory neurons.

Ozkan ED, Creson TK, Kramár EA, Rojas C, Seese RR, Babyan AH, Shi Y, Lucero R, Xu X, Noebels JL, Miller CA, Lynch G, Rumbaugh G.

Neuron. 2014 Jun 18;82(6):1317-33. doi: 10.1016/j.neuron.2014.05.015.


Efficacy of lovastatin on learning and memory deficits caused by chronic intermittent hypoxia-hypercapnia: through regulation of NR2B-containing NMDA receptor-ERK pathway.

Huo XL, Min JJ, Pan CY, Zhao CC, Pan LL, Gui FF, Jin L, Wang XT.

PLoS One. 2014 Apr 9;9(4):e94278. doi: 10.1371/journal.pone.0094278. eCollection 2014.


Neurofibromin is the major ras inactivator in dendritic spines.

Oliveira AF, Yasuda R.

J Neurosci. 2014 Jan 15;34(3):776-83. doi: 10.1523/JNEUROSCI.3096-13.2014.


SynGAP regulates protein synthesis and homeostatic synaptic plasticity in developing cortical networks.

Wang CC, Held RG, Hall BJ.

PLoS One. 2013 Dec 31;8(12):e83941. doi: 10.1371/journal.pone.0083941. eCollection 2013.


Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.

Pozniak CD, Sengupta Ghosh A, Gogineni A, Hanson JE, Lee SH, Larson JL, Solanoy H, Bustos D, Li H, Ngu H, Jubb AM, Ayalon G, Wu J, Scearce-Levie K, Zhou Q, Weimer RM, Kirkpatrick DS, Lewcock JW.

J Exp Med. 2013 Nov 18;210(12):2553-67. doi: 10.1084/jem.20122832. Epub 2013 Oct 28.


Expression of non-protein-coding antisense RNAs in genomic regions related to autism spectrum disorders.

Velmeshev D, Magistri M, Faghihi MA.

Mol Autism. 2013 Sep 4;4(1):32. doi: 10.1186/2040-2392-4-32.


Camkii-mediated phosphorylation regulates distributions of Syngap-α1 and -α2 at the postsynaptic density.

Yang Y, Tao-Cheng JH, Bayer KU, Reese TS, Dosemeci A.

PLoS One. 2013 Aug 13;8(8):e71795. doi: 10.1371/journal.pone.0071795. eCollection 2013.


Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses.

Won H, Mah W, Kim E.

Front Mol Neurosci. 2013 Aug 5;6:19. doi: 10.3389/fnmol.2013.00019. eCollection 2013.


AGAP3 and Arf6 regulate trafficking of AMPA receptors and synaptic plasticity.

Oku Y, Huganir RL.

J Neurosci. 2013 Jul 31;33(31):12586-98. doi: 10.1523/JNEUROSCI.0341-13.2013.


SYNGAP1 links the maturation rate of excitatory synapses to the duration of critical-period synaptic plasticity.

Clement JP, Ozkan ED, Aceti M, Miller CA, Rumbaugh G.

J Neurosci. 2013 Jun 19;33(25):10447-52. doi: 10.1523/JNEUROSCI.0765-13.2013.


Modulation of behavior by scaffolding proteins of the post-synaptic density.

Gao C, Tronson NC, Radulovic J.

Neurobiol Learn Mem. 2013 Oct;105:3-12. doi: 10.1016/j.nlm.2013.04.014. Epub 2013 May 20. Review.

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