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Early protective role of MST1 knockdown in response to experimental diabetic nephropathy.

Wu W, Zhang M, Ou S, Liu X, Xue L, Liu J, Wu Y, Li Y, Liu Q.

Am J Transl Res. 2016 Mar 15;8(3):1397-411. eCollection 2016.


Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation.

Meng F, Zhou R, Wu S, Zhang Q, Jin Q, Zhou Y, Plouffe SW, Liu S, Song H, Xia Z, Zhao B, Ye S, Feng XH, Guan KL, Zou J, Xu P.

Genes Dev. 2016 May 1;30(9):1086-100. doi: 10.1101/gad.277533.116. Epub 2016 Apr 28.


The hippo signaling pathway: implications for heart regeneration and disease.

Del Re DP.

Clin Transl Med. 2014 Dec;3(1):27. doi: 10.1186/s40169-014-0027-0. Epub 2014 Sep 16.


Defective Leukocyte Adhesion and Chemotaxis Contributes to Combined Immunodeficiency in Humans with Autosomal Recessive MST1 Deficiency.

Dang TS, Willet JD, Griffin HR, Morgan NV, O'Boyle G, Arkwright PD, Hughes SM, Abinun M, Tee LJ, Barge D, Engelhardt KR, Jackson M, Cant AJ, Maher ER, Koref MS, Reynard LN, Ali S, Hambleton S.

J Clin Immunol. 2016 Feb;36(2):117-22. doi: 10.1007/s10875-016-0232-2. Epub 2016 Jan 22. Erratum in: J Clin Immunol. 2016 Apr;36(3):336-7.


The hippo pathway in heart development, regeneration, and diseases.

Zhou Q, Li L, Zhao B, Guan KL.

Circ Res. 2015 Apr 10;116(8):1431-47. doi: 10.1161/CIRCRESAHA.116.303311. Review.


Regulation of mammalian Ste20 (Mst) kinases.

Rawat SJ, Chernoff J.

Trends Biochem Sci. 2015 Mar;40(3):149-56. doi: 10.1016/j.tibs.2015.01.001. Epub 2015 Feb 6. Review.


Mst1 inhibition rescues β1-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis.

Lee GJ, Yan L, Vatner DE, Vatner SF.

Basic Res Cardiol. 2015 Mar;110(2):7. doi: 10.1007/s00395-015-0461-1. Epub 2015 Jan 20.


Activation of pro-survival CaMK4β/CREB and pro-death MST1 signaling at early and late times during a mouse model of prion disease.

Shott RH, Majer A, Frost KL, Booth SA, Schang LM.

Virol J. 2014 Sep 2;11:160. doi: 10.1186/1743-422X-11-160.


hMOB3 modulates MST1 apoptotic signaling and supports tumor growth in glioblastoma multiforme.

Tang F, Zhang L, Xue G, Hynx D, Wang Y, Cron PD, Hundsrucker C, Hergovich A, Frank S, Hemmings BA, Schmitz-Rohmer D.

Cancer Res. 2014 Jul 15;74(14):3779-89. doi: 10.1158/0008-5472.CAN-13-3430. Epub 2014 May 28.


Mst1 promotes cardiac myocyte apoptosis through phosphorylation and inhibition of Bcl-xL.

Del Re DP, Matsuda T, Zhai P, Maejima Y, Jain MR, Liu T, Li H, Hsu CP, Sadoshima J.

Mol Cell. 2014 May 22;54(4):639-50. doi: 10.1016/j.molcel.2014.04.007. Epub 2014 May 8.


Functional roles of p38 mitogen-activated protein kinase in macrophage-mediated inflammatory responses.

Yang Y, Kim SC, Yu T, Yi YS, Rhee MH, Sung GH, Yoo BC, Cho JY.

Mediators Inflamm. 2014;2014:352371. doi: 10.1155/2014/352371. Epub 2014 Mar 20. Review.


MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes.

Ardestani A, Paroni F, Azizi Z, Kaur S, Khobragade V, Yuan T, Frogne T, Tao W, Oberholzer J, Pattou F, Kerr Conte J, Maedler K.

Nat Med. 2014 Apr;20(4):385-97. doi: 10.1038/nm.3482. Epub 2014 Mar 16.


An unbiased proteomic screen reveals caspase cleavage is positively and negatively regulated by substrate phosphorylation.

Turowec JP, Zukowski SA, Knight JD, Smalley DM, Graves LM, Johnson GL, Li SS, Lajoie GA, Litchfield DW.

Mol Cell Proteomics. 2014 May;13(5):1184-97. doi: 10.1074/mcp.M113.037374. Epub 2014 Feb 20.


Mst1 and Mst2 kinases: regulations and diseases.

Qin F, Tian J, Zhou D, Chen L.

Cell Biosci. 2013 Aug 28;3(1):31. doi: 10.1186/2045-3701-3-31.


Caspase-dependent regulation of the ubiquitin-proteasome system through direct substrate targeting.

Yeh TC, Bratton SB.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14284-9. doi: 10.1073/pnas.1306179110. Epub 2013 Aug 12.


MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS.

Lee JK, Shin JH, Hwang SG, Gwag BJ, McKee AC, Lee J, Kowall NW, Ryu H, Lim DS, Choi EJ.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12066-71. doi: 10.1073/pnas.1300894110. Epub 2013 Jul 1.


FoxO3a is activated and executes neuron death via Bim in response to β-amyloid.

Sanphui P, Biswas SC.

Cell Death Dis. 2013 May 9;4:e625. doi: 10.1038/cddis.2013.148.


MST1, a key player, in enhancing fast skeletal muscle atrophy.

Wei B, Dui W, Liu D, Xing Y, Yuan Z, Ji G.

BMC Biol. 2013 Feb 1;11:12. doi: 10.1186/1741-7007-11-12.


Ste20-like kinase SLK, at the crossroads: a matter of life and death.

Al-Zahrani KN, Baron KD, Sabourin LA.

Cell Adh Migr. 2013 Jan-Feb;7(1):1-10. doi: 10.4161/cam.22495. Epub 2012 Nov 15. Review.


Germinal center kinases in immune regulation.

Yin H, Shi Z, Jiao S, Chen C, Wang W, Greene MI, Zhou Z.

Cell Mol Immunol. 2012 Nov;9(6):439-45. doi: 10.1038/cmi.2012.30. Epub 2012 Sep 10. Review.

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