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Results: 1 to 20 of 27

1.

Intracellular Protein Degradation: From a Vague Idea through the Lysosome and the Ubiquitin-Proteasome System and onto Human Diseases and Drug Targeting.

Ciechanover A.

Rambam Maimonides Med J. 2012 Jan 31;3(1):e0001. doi: 10.5041/RMMJ.10068. Print 2012 Jan.

PMID:
23908826
[PubMed]
Free PMC Article
2.

Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death.

Lima H Jr, Jacobson LS, Goldberg MF, Chandran K, Diaz-Griffero F, Lisanti MP, Brojatsch J.

Cell Cycle. 2013 Jun 15;12(12):1868-78. doi: 10.4161/cc.24903. Epub 2013 May 20.

PMID:
23708522
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The role of chaperone-mediated autophagy in huntingtin degradation.

Qi L, Zhang XD, Wu JC, Lin F, Wang J, DiFiglia M, Qin ZH.

PLoS One. 2012;7(10):e46834. doi: 10.1371/journal.pone.0046834. Epub 2012 Oct 11.

PMID:
23071649
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Crystallization and preliminary X-ray crystallographic analysis of the Bag2 amino-terminal domain from Mus musculus.

Page RC, Xu Z, Amick J, Nix JC, Misra S.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jun 1;68(Pt 6):647-51. doi: 10.1107/S1744309112013267. Epub 2012 May 23.

PMID:
22684061
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Autophagy and disease: always two sides to a problem.

Sridhar S, Botbol Y, Macian F, Cuervo AM.

J Pathol. 2012 Jan;226(2):255-73. doi: 10.1002/path.3025. Epub 2011 Nov 23. Review.

PMID:
21990109
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons.

Liang Q, Ouyang X, Schneider L, Zhang J.

Mol Neurodegener. 2011 Jun 1;6:37. doi: 10.1186/1750-1326-6-37.

PMID:
21631942
[PubMed]
Free PMC Article
7.

LAMP-2-deficient human B cells exhibit altered MHC class II presentation of exogenous antigens.

Crotzer VL, Glosson N, Zhou D, Nishino I, Blum JS.

Immunology. 2010 Nov;131(3):318-30. doi: 10.1111/j.1365-2567.2010.03309.x.

PMID:
20518820
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Lysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease.

Schneider L, Zhang J.

Mol Neurodegener. 2010 Apr 13;5:14. doi: 10.1186/1750-1326-5-14.

PMID:
20388210
[PubMed]
Free PMC Article
9.

mTOR's role in ageing: protein synthesis or autophagy?

Hands SL, Proud CG, Wyttenbach A.

Aging (Albany NY). 2009 Jul 20;1(7):586-97. Review.

PMID:
20157541
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Antigen processing via autophagy--not only for MHC class II presentation anymore?

Münz C.

Curr Opin Immunol. 2010 Feb;22(1):89-93. doi: 10.1016/j.coi.2010.01.016. Epub 2010 Feb 9. Review.

PMID:
20149615
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Lysosomes as "suicide bags" in cell death: myth or reality?

Turk B, Turk V.

J Biol Chem. 2009 Aug 14;284(33):21783-7. doi: 10.1074/jbc.R109.023820. Epub 2009 May 27. Review. No abstract available.

PMID:
19473965
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2.

Bae D, Lu S, Taglienti CA, Mercurio AM.

J Biol Chem. 2008 Oct 17;283(42):28074-80. doi: 10.1074/jbc.M804203200. Epub 2008 Aug 14.

PMID:
18708346
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mechanisms for Hsp70 secretion: crossing membranes without a leader.

Mambula SS, Stevenson MA, Ogawa K, Calderwood SK.

Methods. 2007 Nov;43(3):168-75. Review.

PMID:
17920512
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Neurolysosomal pathology in human prosaposin deficiency suggests essential neurotrophic function of prosaposin.

Sikora J, Harzer K, Elleder M.

Acta Neuropathol. 2007 Feb;113(2):163-75. Epub 2006 Oct 6.

PMID:
17024494
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Autophagy and intracellular surveillance: Modulating MHC class II antigen presentation with stress.

Crotzer VL, Blum JS.

Proc Natl Acad Sci U S A. 2005 May 31;102(22):7779-80. Epub 2005 May 23. No abstract available.

PMID:
15911750
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Neurodegeneration and neuroprotection in Parkinson disease.

Fahn S, Sulzer D.

NeuroRx. 2004 Jan;1(1):139-54. Review.

PMID:
15717014
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Fusobacterium nucleatum increases collagenase 3 production and migration of epithelial cells.

Uitto VJ, Baillie D, Wu Q, Gendron R, Grenier D, Putnins EE, Kanervo A, Firth JD.

Infect Immun. 2005 Feb;73(2):1171-9.

PMID:
15664960
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Activation of chaperone-mediated autophagy during oxidative stress.

Kiffin R, Christian C, Knecht E, Cuervo AM.

Mol Biol Cell. 2004 Nov;15(11):4829-40. Epub 2004 Aug 25.

PMID:
15331765
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Disturbed cholesterol traffic but normal proteolytic function in LAMP-1/LAMP-2 double-deficient fibroblasts.

Eskelinen EL, Schmidt CK, Neu S, Willenborg M, Fuertes G, Salvador N, Tanaka Y, Lüllmann-Rauch R, Hartmann D, Heeren J, von Figura K, Knecht E, Saftig P.

Mol Biol Cell. 2004 Jul;15(7):3132-45. Epub 2004 Apr 30.

PMID:
15121881
[PubMed - indexed for MEDLINE]
Free PMC Article

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