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Results: 1 to 20 of 26

1.

A type-II positive allosteric modulator of α7 nAChRs reduces brain injury and improves neurological function after focal cerebral ischemia in rats.

Sun F, Jin K, Uteshev VV.

PLoS One. 2013 Aug 9;8(8):e73581. doi: 10.1371/journal.pone.0073581. eCollection 2013.

PMID:
23951360
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Activation of the α7 nicotinic ACh receptor induces anxiogenic effects in rats which is blocked by a 5-HT₁a receptor antagonist.

Pandya AA, Yakel JL.

Neuropharmacology. 2013 Jul;70:35-42. doi: 10.1016/j.neuropharm.2013.01.004. Epub 2013 Jan 12.

PMID:
23321689
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Variable maternal stress in rats alters locomotor activity, social behavior, and recognition memory in the adult offspring.

Wilson CA, Terry AV Jr.

Pharmacol Biochem Behav. 2013 Mar;104:47-61. doi: 10.1016/j.pbb.2012.12.015. Epub 2012 Dec 31.

PMID:
23287801
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Enhancement of nicotinic receptors alleviates cytotoxicity in neurological disease models.

Kawamata J, Suzuki S, Shimohama S.

Ther Adv Chronic Dis. 2011 May;2(3):197-208. doi: 10.1177/2040622310397691.

PMID:
23251750
[PubMed]
Free PMC Article
5.

Nicotinic mechanisms in the treatment of psychotic disorders: a focus on the α7 nicotinic receptor.

Olincy A, Freedman R.

Handb Exp Pharmacol. 2012;(213):211-32. doi: 10.1007/978-3-642-25758-2_8. Review.

PMID:
23027417
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

'Old drugs for new applications': can orthopedic research benefit from this strategy?

Pan X, Cheng W, Wang J, Qin L, Lai Y, Tang J, Shang P, Ren P, Zhang P.

Ther Adv Musculoskelet Dis. 2011 Aug;3(4):201-5. doi: 10.1177/1759720X11408487.

PMID:
22870479
[PubMed]
Free PMC Article
7.

Somatic integration of single ion channel responses of α7 nicotinic acetylcholine receptors enhanced by PNU-120596.

Uteshev VV.

PLoS One. 2012;7(3):e32951. doi: 10.1371/journal.pone.0032951. Epub 2012 Mar 30.

PMID:
22479351
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

α7 nicotinic ACh receptors as a ligand-gated source of Ca(2+) ions: the search for a Ca(2+) optimum.

Uteshev VV.

Adv Exp Med Biol. 2012;740:603-38. doi: 10.1007/978-94-007-2888-2_27. Review.

PMID:
22453962
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory.

Pocivavsek A, Wu HQ, Potter MC, Elmer GI, Pellicciari R, Schwarcz R.

Neuropsychopharmacology. 2011 Oct;36(11):2357-67. doi: 10.1038/npp.2011.127. Epub 2011 Jul 27.

PMID:
21796108
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: advantages and limitations.

Williams DK, Wang J, Papke RL.

Biochem Pharmacol. 2011 Oct 15;82(8):915-30. doi: 10.1016/j.bcp.2011.05.001. Epub 2011 May 14. Review.

PMID:
21575610
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Activation of functional α7-containing nAChRs in hippocampal CA1 pyramidal neurons by physiological levels of choline in the presence of PNU-120596.

Kalappa BI, Gusev AG, Uteshev VV.

PLoS One. 2010 Nov 12;5(11):e13964. doi: 10.1371/journal.pone.0013964.

PMID:
21103043
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia.

Coyle JT, Balu D, Benneyworth M, Basu A, Roseman A.

Dialogues Clin Neurosci. 2010;12(3):359-82. Review.

PMID:
20954431
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Nicotinic receptors on rat alveolar macrophages dampen ATP-induced increase in cytosolic calcium concentration.

Mikulski Z, Hartmann P, Jositsch G, Zasłona Z, Lips KS, Pfeil U, Kurzen H, Lohmeyer J, Clauss WG, Grau V, Fronius M, Kummer W.

Respir Res. 2010 Sep 29;11:133. doi: 10.1186/1465-9921-11-133.

PMID:
20920278
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Discovery of novel alpha7 nicotinic receptor antagonists.

Peng Y, Zhang Q, Snyder GL, Zhu H, Yao W, Tomesch J, Papke RL, O'Callaghan JP, Welsh WJ, Wennogle LP.

Bioorg Med Chem Lett. 2010 Aug 15;20(16):4825-30. doi: 10.1016/j.bmcl.2010.06.103. Epub 2010 Jun 25.

PMID:
20638843
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Continuous administration of a selective alpha7 nicotinic partial agonist, DMXBA, improves sensory inhibition without causing tachyphylaxis or receptor upregulation in DBA/2 mice.

Stevens KE, Cornejo B, Adams CE, Zheng L, Yonchek J, Hoffman KL, Christians U, Kem WR.

Brain Res. 2010 Sep 17;1352:140-6. doi: 10.1016/j.brainres.2010.06.063. Epub 2010 Jul 3.

PMID:
20599427
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats.

Loram LC, Harrison JA, Chao L, Taylor FR, Reddy A, Travis CL, Giffard R, Al-Abed Y, Tracey K, Maier SF, Watkins LR.

Brain Behav Immun. 2010 Aug;24(6):959-67. doi: 10.1016/j.bbi.2010.03.008. Epub 2010 Mar 28.

PMID:
20353818
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A reversible model of the cognitive impairment associated with schizophrenia in monkeys: potential therapeutic effects of two nicotinic acetylcholine receptor agonists.

Buccafusco JJ, Terry AV Jr.

Biochem Pharmacol. 2009 Oct 1;78(7):852-62. doi: 10.1016/j.bcp.2009.06.102. Epub 2009 Jul 3.

PMID:
19577545
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Scientific and clinical challenges in sepsis.

Ulloa L, Brunner M, Ramos L, Deitch EA.

Curr Pharm Des. 2009;15(16):1918-35. Review.

PMID:
19519432
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Interaction of benzylidene-anabaseine analogues with agonist and allosteric sites on muscle nicotinic acetylcholine receptors.

Arias HR, Xing H, Macdougall K, Blanton MP, Soti F, Kem WR.

Br J Pharmacol. 2009 May;157(2):320-30. doi: 10.1111/j.1476-5381.2009.00156.x. Epub 2009 Mar 26.

PMID:
19338581
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

High throughput electrophysiology with Xenopus oocytes.

Papke RL, Smith-Maxwell C.

Comb Chem High Throughput Screen. 2009 Jan;12(1):38-50. Review.

PMID:
19149490
[PubMed - indexed for MEDLINE]
Free PMC Article
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