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Results: 17

1.

Effects of Trichostatin A on Cumulus Expansion during Mouse Oocyte Maturation.

Du M, Fu X, Zhou Y, Zhu S.

Asian-Australas J Anim Sci. 2013 Nov;26(11):1545-52. doi: 10.5713/ajas.2013.13128.

PMID:
25049740
[PubMed]
Free PMC Article
2.

Trichostatin A targets the mitochondrial respiratory chain, increasing mitochondrial reactive oxygen species production to trigger apoptosis in human breast cancer cells.

Sun S, Han Y, Liu J, Fang Y, Tian Y, Zhou J, Ma D, Wu P.

PLoS One. 2014 Mar 13;9(3):e91610. doi: 10.1371/journal.pone.0091610. eCollection 2014.

PMID:
24626188
[PubMed - in process]
Free PMC Article
3.

Study of marine natural products including resorcyclic acid lactones from Humicola fuscoatra that reactivate latent HIV-1 expression in an in vitro model of central memory CD4+ T cells.

Mejia EJ, Loveridge ST, Stepan G, Tsai A, Jones GS, Barnes T, White KN, Drašković M, Tenney K, Tsiang M, Geleziunas R, Cihlar T, Pagratis N, Tian Y, Yu H, Crews P.

J Nat Prod. 2014 Mar 28;77(3):618-24. doi: 10.1021/np400889x. Epub 2014 Feb 4.

PMID:
24495105
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brain.

Seo YJ, Muench L, Reid A, Chen J, Kang Y, Hooker JM, Volkow ND, Fowler JS, Kim SW.

Bioorg Med Chem Lett. 2013 Dec 15;23(24):6700-5. doi: 10.1016/j.bmcl.2013.10.038. Epub 2013 Oct 30.

PMID:
24210501
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Small chemical chromatin effectors alter secondary metabolite production in Aspergillus clavatus.

Zutz C, Gacek A, Sulyok M, Wagner M, Strauss J, Rychli K.

Toxins (Basel). 2013 Oct 7;5(10):1723-41. doi: 10.3390/toxins5101723.

PMID:
24105402
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Histone deacetylase inhibitors: clinical implications for hematological malignancies.

Tambaro FP, Dell'aversana C, Carafa V, Nebbioso A, Radic B, Ferrara F, Altucci L.

Clin Epigenetics. 2010 Sep;1(1-2):25-44. doi: 10.1007/s13148-010-0006-2. Epub 2010 Jul 28.

PMID:
22704087
[PubMed]
Free PMC Article
7.

FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors.

Makala L, Di Maro S, Lou TF, Sivanand S, Ahn JM, Pace BS.

Anemia. 2012;2012:428137. doi: 10.1155/2012/428137. Epub 2012 May 14.

PMID:
22655179
[PubMed]
Free PMC Article
8.

Discovery and mechanism of natural products as modulators of histone acetylation.

Salvador LA, Luesch H.

Curr Drug Targets. 2012 Jul;13(8):1029-47. Review.

PMID:
22594471
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists.

Mossman D, Kim KT, Scott RJ.

BMC Cancer. 2010 Jul 12;10:366. doi: 10.1186/1471-2407-10-366.

PMID:
20618997
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Preclinical studies of chemotherapy using histone deacetylase inhibitors in endometrial cancer.

Takai N, Narahara H.

Obstet Gynecol Int. 2010;2010:923824. doi: 10.1155/2010/923824. Epub 2010 Feb 4.

PMID:
20169171
[PubMed]
Free PMC Article
11.

Modulating polo-like kinase 1 as a means for cancer chemoprevention.

Schmit TL, Ledesma MC, Ahmad N.

Pharm Res. 2010 Jun;27(6):989-98. doi: 10.1007/s11095-010-0051-8. Epub 2010 Jan 27. Review.

PMID:
20107874
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor.

Bowers A, West N, Taunton J, Schreiber SL, Bradner JE, Williams RM.

J Am Chem Soc. 2008 Aug 20;130(33):11219-22. doi: 10.1021/ja8033763. Epub 2008 Jul 19.

PMID:
18642817
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy.

Avila AM, Burnett BG, Taye AA, Gabanella F, Knight MA, Hartenstein P, Cizman Z, Di Prospero NA, Pellizzoni L, Fischbeck KH, Sumner CJ.

J Clin Invest. 2007 Mar;117(3):659-71. Epub 2007 Feb 22.

PMID:
17318264
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Drug discovery from natural sources.

Chin YW, Balunas MJ, Chai HB, Kinghorn AD.

AAPS J. 2006 Apr 14;8(2):E239-53.

PMID:
16796374
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Natural product-based inhibitors of hypoxia-inducible factor-1 (HIF-1).

Nagle DG, Zhou YD.

Curr Drug Targets. 2006 Mar;7(3):355-69. Review.

PMID:
16515532
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Isoprenoid biosynthesis as a target for antibacterial and antiparasitic drugs: phosphonohydroxamic acids as inhibitors of deoxyxylulose phosphate reducto-isomerase.

Kuntz L, Tritsch D, Grosdemange-Billiard C, Hemmerlin A, Willem A, Bach TJ, Rohmer M.

Biochem J. 2005 Feb 15;386(Pt 1):127-35.

PMID:
15473867
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Activation of the growth-differentiation factor 11 gene by the histone deacetylase (HDAC) inhibitor trichostatin A and repression by HDAC3.

Zhang X, Wharton W, Yuan Z, Tsai SC, Olashaw N, Seto E.

Mol Cell Biol. 2004 Jun;24(12):5106-18.

PMID:
15169878
[PubMed - indexed for MEDLINE]
Free PMC Article
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