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The non-homologous end-joining pathway of S. cerevisiae works effectively in G1-phase cells, and religates cognate ends correctly and non-randomly.

Gao S, Honey S, Futcher B, Grollman AP.

DNA Repair (Amst). 2016 Jun;42:1-10. doi: 10.1016/j.dnarep.2016.03.013. Epub 2016 Apr 14.


Investigation of the DNA damage response to SFOM-0046, a new small-molecule drug inducing DNA double-strand breaks.

Pauty J, Côté MF, Rodrigue A, Velic D, Masson JY, Fortin S.

Sci Rep. 2016 Mar 22;6:23302. doi: 10.1038/srep23302.


Yeast homologous recombination-based promoter engineering for the activation of silent natural product biosynthetic gene clusters.

Montiel D, Kang HS, Chang FY, Charlop-Powers Z, Brady SF.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):8953-8. doi: 10.1073/pnas.1507606112. Epub 2015 Jul 6.


Requirement of POL3 and POL4 on non-homologous and microhomology-mediated end joining in rad50/xrs2 mutants of Saccharomyces cerevisiae.

Galli A, Chan CY, Parfenova L, Cervelli T, Schiestl RH.

Mutagenesis. 2015 Nov;30(6):841-9. doi: 10.1093/mutage/gev046. Epub 2015 Jun 29.


Alternative Okazaki Fragment Ligation Pathway by DNA Ligase III.

Arakawa H, Iliakis G.

Genes (Basel). 2015 Jun 23;6(2):385-98. doi: 10.3390/genes6020385. Review.


Polymerase Θ is a key driver of genome evolution and of CRISPR/Cas9-mediated mutagenesis.

van Schendel R, Roerink SF, Portegijs V, van den Heuvel S, Tijsterman M.

Nat Commun. 2015 Jun 16;6:7394. doi: 10.1038/ncomms8394.


Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair.

Liu P, Gan W, Guo C, Xie A, Gao D, Guo J, Zhang J, Willis N, Su A, Asara JM, Scully R, Wei W.

Mol Cell. 2015 Feb 19;57(4):648-61. doi: 10.1016/j.molcel.2015.01.005. Epub 2015 Feb 5.


DNA ligase C1 mediates the LigD-independent nonhomologous end-joining pathway of Mycobacterium smegmatis.

Bhattarai H, Gupta R, Glickman MS.

J Bacteriol. 2014 Oct;196(19):3366-76. doi: 10.1128/JB.01832-14. Epub 2014 Jun 23.


Non-homologous end joining often uses microhomology: implications for alternative end joining.

Pannunzio NR, Li S, Watanabe G, Lieber MR.

DNA Repair (Amst). 2014 May;17:74-80. doi: 10.1016/j.dnarep.2014.02.006. Epub 2014 Mar 7. Review.


A role for XLF in DNA repair and recombination in human somatic cells.

Fattah FJ, Kweon J, Wang Y, Lee EH, Kan Y, Lichter N, Weisensel N, Hendrickson EA.

DNA Repair (Amst). 2014 Mar;15:39-53. doi: 10.1016/j.dnarep.2013.12.006. Epub 2014 Jan 21.


The C-terminus of Nej1 is critical for nuclear localization and non-homologous end-joining.

Mahaney BL, Lees-Miller SP, Cobb JA.

DNA Repair (Amst). 2014 Feb;14:9-16. doi: 10.1016/j.dnarep.2013.12.002. Epub 2013 Dec 24.


Chromatin modifications associated with DNA double-strand breaks repair as potential targets for neurological diseases.

Brochier C, Langley B.

Neurotherapeutics. 2013 Oct;10(4):817-30. doi: 10.1007/s13311-013-0210-9. Review.


The fate of linear DNA in Saccharomyces cerevisiae and Candida glabrata: the role of homologous and non-homologous end joining.

Corrigan MW, Kerwin-Iosue CL, Kuczmarski AS, Amin KB, Wykoff DD.

PLoS One. 2013 Jul 24;8(7):e69628. doi: 10.1371/journal.pone.0069628. Print 2013.


Saccharomyces cerevisiae DNA ligase IV supports imprecise end joining independently of its catalytic activity.

Chiruvella KK, Liang Z, Birkeland SR, Basrur V, Wilson TE.

PLoS Genet. 2013 Jun;9(6):e1003599. doi: 10.1371/journal.pgen.1003599. Epub 2013 Jun 27.


Unligated Okazaki Fragments Induce PCNA Ubiquitination and a Requirement for Rad59-Dependent Replication Fork Progression.

Nguyen HD, Becker J, Thu YM, Costanzo M, Koch EN, Smith S, Myung K, Myers CL, Boone C, Bielinsky AK.

PLoS One. 2013 Jun 18;8(6):e66379. doi: 10.1371/journal.pone.0066379. Print 2013.


Basic mechanisms of therapeutic resistance to radiation and chemotherapy in lung cancer.

Willers H, Azzoli CG, Santivasi WL, Xia F.

Cancer J. 2013 May-Jun;19(3):200-7. doi: 10.1097/PPO.0b013e318292e4e3. Review.


Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.

Truong LN, Li Y, Shi LZ, Hwang PY, He J, Wang H, Razavian N, Berns MW, Wu X.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7720-5. doi: 10.1073/pnas.1213431110. Epub 2013 Apr 22.


Lif1 SUMOylation and its role in non-homologous end-joining.

Vigasova D, Sarangi P, Kolesar P, Vlasáková D, Slezakova Z, Altmannova V, Nikulenkov F, Anrather D, Gith R, Zhao X, Chovanec M, Krejci L.

Nucleic Acids Res. 2013 May 1;41(10):5341-53. doi: 10.1093/nar/gkt236. Epub 2013 Apr 9.


Differential requirement for SUB1 in chromosomal and plasmid double-strand DNA break repair.

Yu L, Volkert MR.

PLoS One. 2013;8(3):e58015. doi: 10.1371/journal.pone.0058015. Epub 2013 Mar 12.


Ovarian cancer and DNA repair: DNA ligase IV as a potential key.

Assis J, Pereira D, Medeiros R.

World J Clin Oncol. 2013 Feb 10;4(1):14-24. doi: 10.5306/wjco.v4.i1.14.

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