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Results: 19

1.

Werner Syndrome-specific induced pluripotent stem cells: recovery of telomere function by reprogramming.

Shimamoto A, Yokote K, Tahara H.

Front Genet. 2015 Jan 29;6:10. doi: 10.3389/fgene.2015.00010. eCollection 2015. Review.

PMID:
25688260
[PubMed]
Free PMC Article
2.

Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture.

Shimamoto A, Kagawa H, Zensho K, Sera Y, Kazuki Y, Osaki M, Oshimura M, Ishigaki Y, Hamasaki K, Kodama Y, Yuasa S, Fukuda K, Hirashima K, Seimiya H, Koyama H, Shimizu T, Takemoto M, Yokote K, Goto M, Tahara H.

PLoS One. 2014 Nov 12;9(11):e112900. doi: 10.1371/journal.pone.0112900. eCollection 2014.

PMID:
25390333
[PubMed - in process]
Free PMC Article
3.

Catalytic activities of Werner protein are affected by adduction with 4-hydroxy-2-nonenal.

Czerwińska J, Poznański J, Dębski J, Bukowy Z, Bohr VA, Tudek B, Speina E.

Nucleic Acids Res. 2014;42(17):11119-35. doi: 10.1093/nar/gku783. Epub 2014 Aug 28.

PMID:
25170083
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Ethnic-Specific WRN Mutations in South Asian Werner Syndrome Patients: Potential Founder Effect in Patients with Indian or Pakistani Ancestry.

Saha B, Lessel D, Nampoothiri S, Rao AS, Hisama FM, Peter D, Bennett C, Nürnberg G, Nürnberg P, Martin GM, Kubisch C, Oshima J.

Mol Genet Genomic Med. 2013 May 1;1(1):7-14.

PMID:
23936869
[PubMed]
Free PMC Article
5.

Pancreatic Adenocarcinoma Associated With Werner's Syndrome (Adult-Onset Progeria).

Chun SG, Yee NS, Holland JM, Shohet RV, Palalay MP, Bryant-Greenwood PK.

Gastrointest Cancer Res. 2011 Jan;4(1):24-8. No abstract available.

PMID:
21464868
[PubMed]
Free PMC Article
6.

Werner syndrome as a hereditary risk factor for exocrine pancreatic cancer: potential role of WRN in pancreatic tumorigenesis and patient-tailored therapy.

Chun SG, Yee NS.

Cancer Biol Ther. 2010 Sep 1;10(5):430-7. doi: 10.4161/cbt.10.5.12763. Epub 2010 Sep 22.

PMID:
20657174
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Werner syndrome gene variants in human sarcomas.

Hsu JJ, Kamath-Loeb AS, Glick E, Wallden B, Swisshelm K, Rubin BP, Loeb LA.

Mol Carcinog. 2010 Feb;49(2):166-74. doi: 10.1002/mc.20586.

PMID:
19824023
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

WRN polymorphisms affect expression levels of plasminogen activator inhibitor type 1 in cultured fibroblasts.

Castro E, Oviedo-Rodríguez V, Angel-Chávez LI.

BMC Cardiovasc Disord. 2008 Feb 29;8:5. doi: 10.1186/1471-2261-8-5.

PMID:
18312663
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Hyperinsulinemia and insulin resistance in Wrn null mice fed a diabetogenic diet.

Moore G, Knoblaugh S, Gollahon K, Rabinovitch P, Ladiges W.

Mech Ageing Dev. 2008 Apr;129(4):201-6. doi: 10.1016/j.mad.2007.12.009. Epub 2008 Jan 17.

PMID:
18295300
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The spectrum of WRN mutations in Werner syndrome patients.

Huang S, Lee L, Hanson NB, Lenaerts C, Hoehn H, Poot M, Rubin CD, Chen DF, Yang CC, Juch H, Dorn T, Spiegel R, Oral EA, Abid M, Battisti C, Lucci-Cordisco E, Neri G, Steed EH, Kidd A, Isley W, Showalter D, Vittone JL, Konstantinow A, Ring J, Meyer P, Wenger SL, von Herbay A, Wollina U, Schuelke M, Huizenga CR, Leistritz DF, Martin GM, Mian IS, Oshima J.

Hum Mutat. 2006 Jun;27(6):558-67.

PMID:
16673358
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Biased exon/intron distribution of cryptic and de novo 3' splice sites.

Královicová J, Christensen MB, Vorechovský I.

Nucleic Acids Res. 2005 Sep 1;33(15):4882-98. Print 2005.

PMID:
16141195
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

RecQ helicases: suppressors of tumorigenesis and premature aging.

Bachrati CZ, Hickson ID.

Biochem J. 2003 Sep 15;374(Pt 3):577-606. Review.

PMID:
12803543
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Werner Syndrome.

Chen L, Oshima J.

J Biomed Biotechnol. 2002;2(2):46-54.

PMID:
12488583
[PubMed - as supplied by publisher]
Free PMC Article
14.

Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA.

Shen JC, Loeb LA.

Nucleic Acids Res. 2000 Sep 1;28(17):3260-8.

PMID:
10954593
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Detection by epitope-defined monoclonal antibodies of Werner DNA helicases in the nucleoplasm and their upregulation by cell transformation and immortalization.

Shiratori M, Sakamoto S, Suzuki N, Tokutake Y, Kawabe Y, Enomoto T, Sugimoto M, Goto M, Matsumoto T, Furuichi Y.

J Cell Biol. 1999 Jan 11;144(1):1-9.

PMID:
9885239
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Disequilibrium likelihoods for fine-scale mapping of a rare allele.

Graham J, Thompson EA.

Am J Hum Genet. 1998 Nov;63(5):1517-30.

PMID:
9792879
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53.

Yamabe Y, Shimamoto A, Goto M, Yokota J, Sugawara M, Furuichi Y.

Mol Cell Biol. 1998 Nov;18(11):6191-200.

PMID:
9774636
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A.

Shen JC, Gray MD, Oshima J, Loeb LA.

Nucleic Acids Res. 1998 Jun 15;26(12):2879-85.

PMID:
9611231
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system.

Suzuki N, Shimamoto A, Imamura O, Kuromitsu J, Kitao S, Goto M, Furuichi Y.

Nucleic Acids Res. 1997 Aug 1;25(15):2973-8.

PMID:
9224595
[PubMed - indexed for MEDLINE]
Free PMC Article
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