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High blood sugar levels significantly impact the prognosis of colorectal cancer patients through down-regulation of microRNA-16 by targeting Myb and VEGFR2.

Yang IP, Tsai HL, Huang CW, Lu CY, Miao ZF, Chang SF, Juo SH, Wang JY.

Oncotarget. 2016 Apr 5;7(14):18837-50. doi: 10.18632/oncotarget.7719.


Targeting Cell Survival Proteins for Cancer Cell Death.

Pandey MK, Prasad S, Tyagi AK, Deb L, Huang J, Karelia DN, Amin SG, Aggarwal BB.

Pharmaceuticals (Basel). 2016 Feb 25;9(1). pii: E11. doi: 10.3390/ph9010011. Review.


Dual-Reporter β-Cell-Specific Male Transgenic Rats for the Analysis of β-Cell Functional Mass and Enrichment by Flow Cytometry.

Ghislain J, Fontés G, Tremblay C, Kebede MA, Poitout V.

Endocrinology. 2016 Mar;157(3):1299-306. doi: 10.1210/en.2015-1550. Epub 2015 Dec 15.


Reduced Ki67 Staining in the Postmortem State Calls Into Question Past Conclusions About the Lack of Turnover of Adult Human β-Cells.

Sullivan BA, Hollister-Lock J, Bonner-Weir S, Weir GC.

Diabetes. 2015 May;64(5):1698-702. doi: 10.2337/db14-1675. Epub 2014 Dec 8.


Anticancer potential of Syzygium aromaticum L. in MCF-7 human breast cancer cell lines.

Kumar PS, Febriyanti RM, Sofyan FF, Luftimas DE, Abdulah R.

Pharmacognosy Res. 2014 Oct;6(4):350-4. doi: 10.4103/0974-8490.138291.


The enigmatic roles of caspases in tumor development.

Jäger R, Zwacka RM.

Cancers (Basel). 2010 Nov 24;2(4):1952-79. doi: 10.3390/cancers2041952.


Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53.

Morad SA, Madigan JP, Levin JC, Abdelmageed N, Karimi R, Rosenberg DW, Kester M, Shanmugavelandy SS, Cabot MC.

Biochem Pharmacol. 2013 Apr 15;85(8):1057-65. doi: 10.1016/j.bcp.2013.01.015. Epub 2013 Jan 24.


Targeting the Bcl-2 family for cancer therapy.

Thomas S, Quinn BA, Das SK, Dash R, Emdad L, Dasgupta S, Wang XY, Dent P, Reed JC, Pellecchia M, Sarkar D, Fisher PB.

Expert Opin Ther Targets. 2013 Jan;17(1):61-75. doi: 10.1517/14728222.2013.733001. Epub 2012 Nov 22. Review.


Hypoxia inducible factor-1α is necessary for invasive phenotype in Vegf-deleted islet cell tumors.

Takeda T, Okuyama H, Nishizawa Y, Tomita S, Inoue M.

Sci Rep. 2012;2:494. doi: 10.1038/srep00494. Epub 2012 Jul 4.


Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: implications for tumor angiogenesis.

Åkerblom B, Zang G, Zhuang ZW, Calounova G, Simons M, Welsh M.

Mol Oncol. 2012 Jun;6(3):333-46. doi: 10.1016/j.molonc.2012.01.006. Epub 2012 Jan 31.


PERK regulates the proliferation and development of insulin-secreting beta-cell tumors in the endocrine pancreas of mice.

Gupta S, McGrath B, Cavener DR.

PLoS One. 2009 Nov 24;4(11):e8008. doi: 10.1371/journal.pone.0008008.


Islet beta-cells deficient in Bcl-xL develop but are abnormally sensitive to apoptotic stimuli.

Carrington EM, McKenzie MD, Jansen E, Myers M, Fynch S, Kos C, Strasser A, Kay TW, Scott CL, Allison J.

Diabetes. 2009 Oct;58(10):2316-23. doi: 10.2337/db08-1602. Epub 2009 Jul 6.


Genetic ablation of Bcl-x attenuates invasiveness without affecting apoptosis or tumor growth in a mouse model of pancreatic neuroendocrine cancer.

Hager JH, Ulanet DB, Hennighausen L, Hanahan D.

PLoS One. 2009;4(2):e4455. doi: 10.1371/journal.pone.0004455. Epub 2009 Feb 11.


Bcl2 family proteins in carcinogenesis and the treatment of cancer.

Frenzel A, Grespi F, Chmelewskij W, Villunger A.

Apoptosis. 2009 Apr;14(4):584-96. doi: 10.1007/s10495-008-0300-z.


Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function.

Kebede M, Favaloro J, Gunton JE, Laybutt DR, Shaw M, Wong N, Fam BC, Aston-Mourney K, Rantzau C, Zulli A, Proietto J, Andrikopoulos S.

Diabetes. 2008 Jul;57(7):1887-95. doi: 10.2337/db07-1326. Epub 2008 Mar 28.


Matrix metalloproteinase-2 regulates vascular patterning and growth affecting tumor cell survival and invasion in GBM.

Du R, Petritsch C, Lu K, Liu P, Haller A, Ganss R, Song H, Vandenberg S, Bergers G.

Neuro Oncol. 2008 Jun;10(3):254-64. doi: 10.1215/15228517-2008-001. Epub 2008 Mar 21.


The tumour-suppressor p53 is not required for pancreatic beta cell death during diabetes and upon irradiation.

Nam SY, Lee MK, Sabapathy K.

J Physiol. 2008 Jan 15;586(2):407-17. Epub 2007 Nov 15.


Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization.

Ding Q, He X, Hsu JM, Xia W, Chen CT, Li LY, Lee DF, Liu JC, Zhong Q, Wang X, Hung MC.

Mol Cell Biol. 2007 Jun;27(11):4006-17. Epub 2007 Mar 26.

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