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Items: 1 to 20 of 36

1.

Ubiquitin-specific protease 7 regulates nucleotide excision repair through deubiquitinating XPC protein and preventing XPC protein from undergoing ultraviolet light-induced and VCP/p97 protein-regulated proteolysis.

He J, Zhu Q, Wani G, Sharma N, Han C, Qian J, Pentz K, Wang QE, Wani AA.

J Biol Chem. 2014 Sep 26;289(39):27278-89. doi: 10.1074/jbc.M114.589812. Epub 2014 Aug 12.

2.

Single-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates.

Ghodke H, Wang H, Hsieh CL, Woldemeskel S, Watkins SC, Rapić-Otrin V, Van Houten B.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):E1862-71. doi: 10.1073/pnas.1323856111. Epub 2014 Apr 23.

3.

DNA damage-binding complex recruits HDAC1 to repress Bcl-2 transcription in human ovarian cancer cells.

Zhao R, Han C, Eisenhauer E, Kroger J, Zhao W, Yu J, Selvendiran K, Liu X, Wani AA, Wang QE.

Mol Cancer Res. 2014 Mar;12(3):370-80. doi: 10.1158/1541-7786.MCR-13-0281. Epub 2013 Nov 18.

4.

The deubiquitinating protein USP24 interacts with DDB2 and regulates DDB2 stability.

Zhang L, Lubin A, Chen H, Sun Z, Gong F.

Cell Cycle. 2012 Dec 1;11(23):4378-84. doi: 10.4161/cc.22688. Epub 2012 Nov 16.

5.

Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair.

Yeh JI, Levine AS, Du S, Chinte U, Ghodke H, Wang H, Shi H, Hsieh CL, Conway JF, Van Houten B, Rapić-Otrin V.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):E2737-46. doi: 10.1073/pnas.1110067109. Epub 2012 Jul 20.

6.

Multiple skin cancers in adults with mutations in the XP-E (DDB2) DNA repair gene.

Oh KS, Emmert S, Tamura D, DiGiovanna JJ, Kraemer KH.

J Invest Dermatol. 2011 Mar;131(3):785-8. doi: 10.1038/jid.2010.352. Epub 2010 Nov 25. No abstract available.

7.

DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA.

Takedachi A, Saijo M, Tanaka K.

Mol Cell Biol. 2010 Jun;30(11):2708-23. doi: 10.1128/MCB.01460-09. Epub 2010 Apr 5.

8.

DDB2 decides cell fate following DNA damage.

Stoyanova T, Roy N, Kopanja D, Bagchi S, Raychaudhuri P.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10690-5. doi: 10.1073/pnas.0812254106. Epub 2009 Jun 16.

9.

Physical and functional interaction between DDB and XPA in nucleotide excision repair.

Wakasugi M, Kasashima H, Fukase Y, Imura M, Imai R, Yamada S, Cleaver JE, Matsunaga T.

Nucleic Acids Res. 2009 Feb;37(2):516-25. doi: 10.1093/nar/gkn964. Epub 2008 Dec 4.

10.

Cellular concentrations of DDB2 regulate dynamic binding of DDB1 at UV-induced DNA damage.

Alekseev S, Luijsterburg MS, Pines A, Geverts B, Mari PO, Giglia-Mari G, Lans H, Houtsmuller AB, Mullenders LH, Hoeijmakers JH, Vermeulen W.

Mol Cell Biol. 2008 Dec;28(24):7402-13. doi: 10.1128/MCB.01108-08. Epub 2008 Oct 20.

11.

Epstein-Barr virus latent membrane protein 1 represses DNA repair through the PI3K/Akt/FOXO3a pathway in human epithelial cells.

Chen YR, Liu MT, Chang YT, Wu CC, Hu CY, Chen JY.

J Virol. 2008 Aug;82(16):8124-37. doi: 10.1128/JVI.00430-08. Epub 2008 Jun 4.

12.

Damaged DNA binding protein 2 plays a role in breast cancer cell growth.

Kattan Z, Marchal S, Brunner E, Ramacci C, Leroux A, Merlin JL, Domenjoud L, Dauça M, Becuwe P.

PLoS One. 2008 Apr 23;3(4):e2002. doi: 10.1371/journal.pone.0002002.

13.

Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repair.

Wang QE, Praetorius-Ibba M, Zhu Q, El-Mahdy MA, Wani G, Zhao Q, Qin S, Patnaik S, Wani AA.

Nucleic Acids Res. 2007;35(16):5338-50. Epub 2007 Aug 9.

14.

Blood-derived gene-expression profiling in unravelling susceptibility to recessive disease.

Vahteristo P, Kokko A, Saksela O, Aittomäki K, Aaltonen LA.

J Med Genet. 2007 Nov;44(11):718-20. Epub 2007 Jul 27.

15.

The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites.

Kapetanaki MG, Guerrero-Santoro J, Bisi DC, Hsieh CL, Rapić-Otrin V, Levine AS.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2588-93. Epub 2006 Feb 10.

17.

Tumor-prone phenotype of the DDB2-deficient mice.

Yoon T, Chakrabortty A, Franks R, Valli T, Kiyokawa H, Raychaudhuri P.

Oncogene. 2005 Jan 13;24(3):469-78.

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