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Results: 1 to 20 of 27

1.

pH-triggered conformational switching along the membrane insertion pathway of the diphtheria toxin T-domain.

Ladokhin AS.

Toxins (Basel). 2013 Aug 6;5(8):1362-80. doi: 10.3390/toxins5081362. Review.

PMID:
23925141
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

pH-triggered conformational switching of the diphtheria toxin T-domain: the roles of N-terminal histidines.

Kurnikov IV, Kyrychenko A, Flores-Canales JC, Rodnin MV, Simakov N, Vargas-Uribe M, Posokhov YO, Kurnikova M, Ladokhin AS.

J Mol Biol. 2013 Aug 9;425(15):2752-64. doi: 10.1016/j.jmb.2013.04.030. Epub 2013 May 3.

PMID:
23648837
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Crucial role of H322 in folding of the diphtheria toxin T-domain into the open-channel state.

Vargas-Uribe M, Rodnin MV, Kienker P, Finkelstein A, Ladokhin AS.

Biochemistry. 2013 May 21;52(20):3457-63. doi: 10.1021/bi400249f. Epub 2013 May 9.

PMID:
23621842
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Probing the interaction of brain fatty acid binding protein (B-FABP) with model membranes.

Dyszy F, Pinto AP, Araújo AP, Costa-Filho AJ.

PLoS One. 2013;8(3):e60198. doi: 10.1371/journal.pone.0060198. Epub 2013 Mar 28.

PMID:
23555925
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Obstructing toxin pathways by targeted pore blockage.

Nestorovich EM, Bezrukov SM.

Chem Rev. 2012 Dec 12;112(12):6388-430. doi: 10.1021/cr300141q. Epub 2012 Oct 11. No abstract available.

PMID:
23057504
[PubMed - in process]
Free PMC Article
6.

Replacement of C-terminal histidines uncouples membrane insertion and translocation in diphtheria toxin T-domain.

Rodnin MV, Kyrychenko A, Kienker P, Sharma O, Vargas-Uribe M, Collier RJ, Finkelstein A, Ladokhin AS.

Biophys J. 2011 Nov 16;101(10):L41-3. doi: 10.1016/j.bpj.2011.10.018. Epub 2011 Nov 15.

PMID:
22098755
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Studies of the mechanistic details of the pH-dependent association of botulinum neurotoxin with membranes.

Mushrush DJ, Koteiche HA, Sammons MA, Link AJ, McHaourab HS, Lacy DB.

J Biol Chem. 2011 Jul 29;286(30):27011-8. doi: 10.1074/jbc.M111.256982. Epub 2011 Jun 7.

PMID:
21652698
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Structural origins of nitroxide side chain dynamics on membrane protein α-helical sites.

Kroncke BM, Horanyi PS, Columbus L.

Biochemistry. 2010 Nov 30;49(47):10045-60. doi: 10.1021/bi101148w. Epub 2010 Nov 8.

PMID:
20964375
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Conformational switching of the diphtheria toxin T domain.

Rodnin MV, Kyrychenko A, Kienker P, Sharma O, Posokhov YO, Collier RJ, Finkelstein A, Ladokhin AS.

J Mol Biol. 2010 Sep 10;402(1):1-7. doi: 10.1016/j.jmb.2010.07.024. Epub 2010 Jul 21.

PMID:
20654627
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Conformational changes in BAK, a pore-forming proapoptotic Bcl-2 family member, upon membrane insertion and direct evidence for the existence of BH3-BH3 contact interface in BAK homo-oligomers.

Oh KJ, Singh P, Lee K, Foss K, Lee S, Park M, Lee S, Aluvila S, Park M, Singh P, Kim RS, Symersky J, Walters DE.

J Biol Chem. 2010 Sep 10;285(37):28924-37. doi: 10.1074/jbc.M110.135293. Epub 2010 Jul 6.

PMID:
20605789
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Kinetic intermediate reveals staggered pH-dependent transitions along the membrane insertion pathway of the diphtheria toxin T-domain.

Kyrychenko A, Posokhov YO, Rodnin MV, Ladokhin AS.

Biochemistry. 2009 Aug 18;48(32):7584-94. doi: 10.1021/bi9009264.

PMID:
19588969
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Endosome fusion induced by diphtheria toxin translocation domain.

Antignani A, Youle RJ.

Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):8020-5. doi: 10.1073/pnas.0711707105. Epub 2008 Jun 6.

PMID:
18539770
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Design and synthesis of single-nanoparticle optical biosensors for imaging and characterization of single receptor molecules on single living cells.

Huang T, Nallathamby PD, Gillet D, Xu XH.

Anal Chem. 2007 Oct 15;79(20):7708-18. Epub 2007 Sep 15.

PMID:
17867652
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Acid destabilization of the solution conformation of Bcl-xL does not drive its pH-dependent insertion into membranes.

Thuduppathy GR, Hill RB.

Protein Sci. 2006 Feb;15(2):248-57. Epub 2005 Dec 29.

PMID:
16385002
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Initial structural and dynamic characterization of the M2 protein transmembrane and amphipathic helices in lipid bilayers.

Tian C, Gao PF, Pinto LH, Lamb RA, Cross TA.

Protein Sci. 2003 Nov;12(11):2597-605.

PMID:
14573870
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

How do helix-helix interactions help determine the folds of membrane proteins? Perspectives from the study of homo-oligomeric helical bundles.

DeGrado WF, Gratkowski H, Lear JD.

Protein Sci. 2003 Apr;12(4):647-65. Review.

PMID:
12649422
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Site-directed spin labeling of a bacterial chemoreceptor reveals a dynamic, loosely packed transmembrane domain.

Barnakov A, Altenbach C, Barnakova L, Hubbell WL, Hazelbauer GL.

Protein Sci. 2002 Jun;11(6):1472-81.

PMID:
12021446
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Topography of diphtheria Toxin's T domain in the open channel state.

Senzel L, Gordon M, Blaustein RO, Oh KJ, Collier RJ, Finkelstein A.

J Gen Physiol. 2000 Apr;115(4):421-34.

PMID:
10736310
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Membrane lysis by the antibacterial peptides cecropins B1 and B3: A spin-label electron spin resonance study on phospholipid bilayers.

Hung SC, Wang W, Chan SI, Chen HM.

Biophys J. 1999 Dec;77(6):3120-33.

PMID:
10585933
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain.

Oh KJ, Senzel L, Collier RJ, Finkelstein A.

Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8467-70.

PMID:
10411898
[PubMed - indexed for MEDLINE]
Free PMC Article

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