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Results: 1 to 20 of 73

1.

Crystal Structures of PRK1 in Complex with the Clinical Compounds Lestaurtinib and Tofacitinib Reveal Ligand Induced Conformational Changes.

Chamberlain P, Delker S, Pagarigan B, Mahmoudi A, Jackson P, Abbasian M, Muir J, Raheja N, Cathers B.

PLoS One. 2014 Aug 11;9(8):e103638. doi: 10.1371/journal.pone.0103638. eCollection 2014.

PMID:
25111382
[PubMed - in process]
Free PMC Article
2.

The Rac1 hypervariable region in targeting and signaling: a tail of many stories.

Lam BD, Hordijk PL.

Small GTPases. 2013 Apr-Jun;4(2):78-89. doi: 10.4161/sgtp.23310. Epub 2013 Jan 25. Review.

PMID:
23354415
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Lysophospholipid receptor activation of RhoA and lipid signaling pathways.

Xiang SY, Dusaban SS, Brown JH.

Biochim Biophys Acta. 2013 Jan;1831(1):213-22. doi: 10.1016/j.bbalip.2012.09.004. Epub 2012 Sep 15. Review.

PMID:
22986288
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Regulation of protein kinase C-related protein kinase 2 (PRK2) by an intermolecular PRK2-PRK2 interaction mediated by Its N-terminal domain.

Bauer AF, Sonzogni S, Meyer L, Zeuzem S, Piiper A, Biondi RM, Neimanis S.

J Biol Chem. 2012 Jun 8;287(24):20590-602. doi: 10.1074/jbc.M111.327437. Epub 2012 Apr 16.

PMID:
22511787
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Genome-wide functional annotation of dual-specificity protein- and lipid-binding modules that regulate protein interactions.

Chen Y, Sheng R, Källberg M, Silkov A, Tun MP, Bhardwaj N, Kurilova S, Hall RA, Honig B, Lu H, Cho W.

Mol Cell. 2012 Apr 27;46(2):226-37. doi: 10.1016/j.molcel.2012.02.012. Epub 2012 Mar 22.

PMID:
22445486
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Structure of the Bro1 domain protein BROX and functional analyses of the ALIX Bro1 domain in HIV-1 budding.

Zhai Q, Landesman MB, Robinson H, Sundquist WI, Hill CP.

PLoS One. 2011;6(12):e27466. doi: 10.1371/journal.pone.0027466. Epub 2011 Dec 5.

PMID:
22162750
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Hypotonic swelling-induced activation of PKN1 mediates cell survival in cardiac myocytes.

Kajimoto K, Shao D, Takagi H, Maceri G, Zablocki D, Mukai H, Ono Y, Sadoshima J.

Am J Physiol Heart Circ Physiol. 2011 Jan;300(1):H191-200. doi: 10.1152/ajpheart.00232.2010. Epub 2010 Oct 29.

PMID:
21037231
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Development of an intracellularly acting inhibitory peptide selective for PKN.

Shiga K, Takayama K, Futaki S, Hutti JE, Cantley LC, Ueki K, Ono Y, Mukai H.

Biochem J. 2009 Dec 23;425(2):445-53. doi: 10.1042/BJ20090380.

PMID:
19857203
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Bacterial toxins induce sustained mRNA expression of the silencing transcription factor klf2 via inactivation of RhoA and Rhophilin 1.

Dach K, Zovko J, Hogardt M, Koch I, van Erp K, Heesemann J, Hoffmann R.

Infect Immun. 2009 Dec;77(12):5583-92. doi: 10.1128/IAI.00121-09. Epub 2009 Sep 28.

PMID:
19786564
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Protein kinase C-related kinase and ROCK are required for thrombin-induced endothelial cell permeability downstream from Galpha12/13 and Galpha11/q.

Gavard J, Gutkind JS.

J Biol Chem. 2008 Oct 31;283(44):29888-96. doi: 10.1074/jbc.M803880200. Epub 2008 Aug 19.

PMID:
18713748
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Fragmentation of protein kinase N (PKN) in the hydrocephalic rat brain.

Okii N, Amano T, Seki T, Matsubayashi H, Mukai H, Ono Y, Kurisu K, Sakai N.

Acta Histochem Cytochem. 2007 Aug 30;40(4):113-21.

PMID:
17898875
[PubMed]
Free PMC Article
12.

A rho-binding protein kinase C-like activity is required for the function of protein kinase N in Drosophila development.

Betson M, Settleman J.

Genetics. 2007 Aug;176(4):2201-12. Epub 2007 May 16.

PMID:
17507675
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease.

Wang L, Hauser ER, Shah SH, Pericak-Vance MA, Haynes C, Crosslin D, Harris M, Nelson S, Hale AB, Granger CB, Haines JL, Jones CJ, Crossman D, Seo D, Gregory SG, Kraus WE, Goldschmidt-Clermont PJ, Vance JM.

Am J Hum Genet. 2007 Apr;80(4):650-63. Epub 2007 Feb 8.

PMID:
17357071
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Large-scale identification of genes implicated in kidney glomerulus development and function.

Takemoto M, He L, Norlin J, Patrakka J, Xiao Z, Petrova T, Bondjers C, Asp J, Wallgard E, Sun Y, Samuelsson T, Mostad P, Lundin S, Miura N, Sado Y, Alitalo K, Quaggin SE, Tryggvason K, Betsholtz C.

EMBO J. 2006 Mar 8;25(5):1160-74. Epub 2006 Feb 23.

PMID:
16498405
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation.

Zhao ZS, Manser E.

Biochem J. 2005 Mar 1;386(Pt 2):201-14. Review.

PMID:
15548136
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Human RAS superfamily proteins and related GTPases.

Colicelli J.

Sci STKE. 2004 Sep 7;2004(250):RE13. Review.

PMID:
15367757
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Formin-dependent actin assembly is regulated by distinct modes of Rho signaling in yeast.

Dong Y, Pruyne D, Bretscher A.

J Cell Biol. 2003 Jun 23;161(6):1081-92. Epub 2003 Jun 16.

PMID:
12810699
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Control of T lymphocyte morphology by the GTPase Rho.

Woodside DG, Wooten DK, Teague TK, Miyamoto YJ, Caudell EG, Udagawa T, Andruss BF, McIntyre BW.

BMC Cell Biol. 2003 Feb 24;4:2. Epub 2003 Feb 24.

PMID:
12600279
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm.

Newton AC.

Biochem J. 2003 Mar 1;370(Pt 2):361-71. Review.

PMID:
12495431
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters.

Fritz G, Brachetti C, Bahlmann F, Schmidt M, Kaina B.

Br J Cancer. 2002 Sep 9;87(6):635-44.

PMID:
12237774
[PubMed - indexed for MEDLINE]
Free PMC Article

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