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Items: 1 to 20 of 87

1.

XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination.

IJspeert H, Rozmus J, Schwarz K, Warren RL, van Zessen D, Holt RA, Pico-Knijnenburg I, Simons E, Jerchel I, Wawer A, Lorenz M, Patıroğlu T, Akar HH, Leite R, Verkaik NS, Stubbs AP, van Gent DC, van Dongen JJ, van der Burg M.

Blood. 2016 Aug 4;128(5):650-9. doi: 10.1182/blood-2016-02-701029. Epub 2016 Jun 8.

2.

Immune Cell Identity: Perspective from a Palimpsest.

Rothenberg EV.

Perspect Biol Med. 2015 Spring;58(2):205-28. doi: 10.1353/pbm.2015.0020.

3.

Rescue of DNA-PK Signaling and T-Cell Differentiation by Targeted Genome Editing in a prkdc Deficient iPSC Disease Model.

Rahman SH, Kuehle J, Reimann C, Mlambo T, Alzubi J, Maeder ML, Riedel H, Fisch P, Cantz T, Rudolph C, Mussolino C, Joung JK, Schambach A, Cathomen T.

PLoS Genet. 2015 May 22;11(5):e1005239. doi: 10.1371/journal.pgen.1005239. eCollection 2015 May.

4.

Predominant role for activation-induced cytidine deaminase in generating IgG anti-nucleosomal antibodies of murine SLE.

Detanico T, Guo W, Wysocki LJ.

J Autoimmun. 2015 Apr;58:67-77. doi: 10.1016/j.jaut.2015.01.006. Epub 2015 Jan 26. Erratum in: J Autoimmun. 2015 Jun;60:86.

5.

Expansion of the preimmune antibody repertoire by junctional diversity in Bos taurus.

Liljavirta J, Niku M, Pessa-Morikawa T, Ekman A, Iivanainen A.

PLoS One. 2014 Jun 13;9(6):e99808. doi: 10.1371/journal.pone.0099808. eCollection 2014.

6.

Functional overlaps between XLF and the ATM-dependent DNA double strand break response.

Kumar V, Alt FW, Oksenych V.

DNA Repair (Amst). 2014 Apr;16:11-22. doi: 10.1016/j.dnarep.2014.01.010. Epub 2014 Feb 20. Review.

7.

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.

Papaemmanuil E, Rapado I, Li Y, Potter NE, Wedge DC, Tubio J, Alexandrov LB, Van Loo P, Cooke SL, Marshall J, Martincorena I, Hinton J, Gundem G, van Delft FW, Nik-Zainal S, Jones DR, Ramakrishna M, Titley I, Stebbings L, Leroy C, Menzies A, Gamble J, Robinson B, Mudie L, Raine K, O'Meara S, Teague JW, Butler AP, Cazzaniga G, Biondi A, Zuna J, Kempski H, Muschen M, Ford AM, Stratton MR, Greaves M, Campbell PJ.

Nat Genet. 2014 Feb;46(2):116-25. doi: 10.1038/ng.2874. Epub 2014 Jan 12.

8.

Human syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development.

Yu X, Almeida JR, Darko S, van der Burg M, DeRavin SS, Malech H, Gennery A, Chinn I, Markert ML, Douek DC, Milner JD.

J Allergy Clin Immunol. 2014 Apr;133(4):1109-15. doi: 10.1016/j.jaci.2013.11.018. Epub 2014 Jan 7.

9.

Mutation of POLB causes lupus in mice.

Senejani AG, Liu Y, Kidane D, Maher SE, Zeiss CJ, Park HJ, Kashgarian M, McNiff JM, Zelterman D, Bothwell AL, Sweasy JB.

Cell Rep. 2014 Jan 16;6(1):1-8. doi: 10.1016/j.celrep.2013.12.017. Epub 2014 Jan 2.

10.

Modulation of Pleurodeles waltl DNA polymerase mu expression by extreme conditions encountered during spaceflight.

Schenten V, Guéguinou N, Baatout S, Frippiat JP.

PLoS One. 2013 Jul 31;8(7):e69647. doi: 10.1371/journal.pone.0069647. Print 2013.

11.

TdIF1 recognizes a specific DNA sequence through its Helix-Turn-Helix and AT-hook motifs to regulate gene transcription.

Kubota T, Koiwai O, Hori K, Watanabe N, Koiwai K.

PLoS One. 2013 Jul 10;8(7):e66710. doi: 10.1371/journal.pone.0066710. Print 2013.

12.

A Novel Quantitative Fluorescent Reporter Assay for RAG Targets and RAG Activity.

Trancoso I, Bonnet M, Gardner R, Carneiro J, Barreto VM, Demengeot J, Sarmento LM.

Front Immunol. 2013 May 16;4:110. doi: 10.3389/fimmu.2013.00110. eCollection 2013.

13.

Exploring the RNA world in hematopoietic cells through the lens of RNA-binding proteins.

Yuan J, Muljo SA.

Immunol Rev. 2013 May;253(1):290-303. doi: 10.1111/imr.12048. Review.

14.

Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?

Strande NT, Waters CA, Ramsden DA.

Genome Integr. 2012 Dec 31;3(1):10. doi: 10.1186/2041-9414-3-10.

15.

Ubiquitylation of terminal deoxynucleotidyltransferase inhibits its activity.

Maezawa S, Fukushima R, Matsushita T, Kato T, Takagaki Y, Nishiyama Y, Ando S, Matsumoto T, Kouda K, Hayano T, Suzuki M, Koiwai K, Koiwai O.

PLoS One. 2012;7(7):e39511. doi: 10.1371/journal.pone.0039511. Epub 2012 Jul 11.

16.

Terminal deoxynucleotidyl transferase requires KU80 and XRCC4 to promote N-addition at non-V(D)J chromosomal breaks in non-lymphoid cells.

Boubakour-Azzouz I, Bertrand P, Claes A, Lopez BS, Rougeon F.

Nucleic Acids Res. 2012 Sep 1;40(17):8381-91. Epub 2012 Jun 27.

17.

The response to and repair of RAG-mediated DNA double-strand breaks.

Helmink BA, Sleckman BP.

Annu Rev Immunol. 2012;30:175-202. doi: 10.1146/annurev-immunol-030409-101320. Epub 2012 Jan 3. Review.

18.

Absence of N addition facilitates B cell development, but impairs immune responses.

Schelonka RL, Ivanov II, Vale AM, Dimmitt RA, Khaled M, Schroeder HW Jr.

Immunogenetics. 2011 Sep;63(9):599-609. doi: 10.1007/s00251-011-0543-7. Epub 2011 Jun 10.

19.

The CDR-H3 repertoire from TdT-deficient adult bone marrow is a close, but not exact, homologue of the CDR-H3 repertoire from perinatal liver.

Schelonka RL, Ivanov II, Vale AM, Szymanska E, Zemlin M, Gartland GL, Schroeder HW Jr.

J Immunol. 2010 Nov 15;185(10):6075-84. doi: 10.4049/jimmunol.1001419. Epub 2010 Oct 18.

20.

On the logic of restrictive recognition of peptide by the T-cell antigen receptor.

Cohn M.

Immunol Res. 2011 May;50(1):49-68. doi: 10.1007/s12026-010-8173-y.

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