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Results: 18

1.

Taking the heart failure battle inside the cell: small molecule targeting of Gβγ subunits.

Kamal FA, Smrcka AV, Blaxall BC.

J Mol Cell Cardiol. 2011 Oct;51(4):462-7. doi: 10.1016/j.yjmcc.2011.01.006. Epub 2011 Jan 21. Review.

PMID:
21256851
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q.

Rebres RA, Roach TI, Fraser ID, Philip F, Moon C, Lin KM, Liu J, Santat L, Cheadle L, Ross EM, Simon MI, Seaman WE.

J Biol Chem. 2011 Jan 14;286(2):942-51. doi: 10.1074/jbc.M110.198200. Epub 2010 Oct 29.

PMID:
21036901
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity.

Jernigan KK, Cselenyi CS, Thorne CA, Hanson AJ, Tahinci E, Hajicek N, Oldham WM, Lee LA, Hamm HE, Hepler JR, Kozasa T, Linder ME, Lee E.

Sci Signal. 2010 May 11;3(121):ra37. doi: 10.1126/scisignal.2000647.

PMID:
20460648
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Multicolor BiFC analysis of competition among G protein beta and gamma subunit interactions.

Hynes TR, Yost E, Mervine S, Berlot CH.

Methods. 2008 Jul;45(3):207-13. doi: 10.1016/j.ymeth.2008.06.008. Epub 2008 Jun 27.

PMID:
18586104
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

G protein betagamma subunits as targets for small molecule therapeutic development.

Smrcka AV, Lehmann DM, Dessal AL.

Comb Chem High Throughput Screen. 2008 Jun;11(5):382-95. Review.

PMID:
18537559
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

G protein βγ subunits: central mediators of G protein-coupled receptor signaling.

Smrcka AV.

Cell Mol Life Sci. 2008 Jul;65(14):2191-214. doi: 10.1007/s00018-008-8006-5. Review.

PMID:
18488142
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Immunohistochemical localization of G protein betagamma subunits in the lateral wall of the rat cochlea.

Khan KM, Sarfaraz N, Siddiqui S, Nawaz H.

J Anat. 2006 Feb;208(2):205-18.

PMID:
16441565
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.

Gibson SK, Gilman AG.

Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):212-7. Epub 2005 Dec 21.

PMID:
16371464
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Mutation of cysteine 214 in Gi1 alpha subunit abolishes its endogenous GTPase activity.

Wang Y, Tawa G, Smith D, Krishnamurthy G, Young KH.

Biochem J. 2004 May 1;379(Pt 3):673-9.

PMID:
14725508
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA.

Hwang JI, Fraser ID, Choi S, Qin XF, Simon MI.

Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):488-93. Epub 2003 Dec 29.

PMID:
14699051
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Independent and synergistic interaction of retinal G-protein subunits with bovine rhodopsin measured by surface plasmon resonance.

Clark WA, Jian X, Chen L, Northup JK.

Biochem J. 2001 Sep 1;358(Pt 2):389-97.

PMID:
11513737
[PubMed - indexed for MEDLINE]
Free PMC Article
12.
13.

Crosstalk between Galpha(i)- and Galpha(q)-coupled receptors is mediated by Gbetagamma exchange.

Quitterer U, Lohse MJ.

Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10626-31.

PMID:
10485876
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Regulation of L-type Ca2+ channels in rabbit portal vein by G protein alphas and betagamma subunits.

Zhong J, Dessauer CW, Keef KD, Hume JR.

J Physiol. 1999 May 15;517 ( Pt 1):109-20.

PMID:
10226153
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Roles of phospholipase C beta2 in chemoattractant-elicited responses.

Jiang H, Kuang Y, Wu Y, Xie W, Simon MI, Wu D.

Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7971-5.

PMID:
9223297
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Effector contributions to G beta gamma-mediated signaling as revealed by muscarinic potassium channel gating.

Ivanova-Nikolova TT, Breitwieser GE.

J Gen Physiol. 1997 Feb;109(2):245-53.

PMID:
9041452
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

G-protein inhibition of phospholipase C-beta 1 in membranes: role of G-protein beta gamma subunits.

Litosch I.

Biochem J. 1996 Oct 1;319 ( Pt 1):173-8.

PMID:
8870665
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A segment of the C-terminal half of the G-protein beta 1 subunit specifies its interaction with the gamma 1 subunit.

Katz A, Simon MI.

Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):1998-2002.

PMID:
7892215
[PubMed - indexed for MEDLINE]
Free PMC Article
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