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Results: 18

Cited In for PubMed (Select 8294000)


Biochemical and structural insights into mesotrypsin: an unusual human trypsin.

Salameh MA, Radisky ES.

Int J Biochem Mol Biol. 2013 Sep 13;4(3):129-39. Review.


PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer.

Hockla A, Miller E, Salameh MA, Copland JA, Radisky DC, Radisky ES.

Mol Cancer Res. 2012 Dec;10(12):1555-66. doi: 10.1158/1541-7786.MCR-12-0314.


The P(2)' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity.

Salameh MA, Soares AS, Hockla A, Radisky DC, Radisky ES.

Biochem J. 2011 Nov 15;440(1):95-105. doi: 10.1042/BJ20110788.


Serine proteases, serine protease inhibitors, and protease-activated receptors: roles in synaptic function and behavior.

Almonte AG, Sweatt JD.

Brain Res. 2011 Aug 17;1407:107-22. doi: 10.1016/j.brainres.2011.06.042. Epub 2011 Jun 24. Review.


Serine proteases mediate inflammatory pain in acute pancreatitis.

Ceppa EP, Lyo V, Grady EF, Knecht W, Grahn S, Peterson A, Bunnett NW, Kirkwood KS, Cattaruzza F.

Am J Physiol Gastrointest Liver Physiol. 2011 Jun;300(6):G1033-42. doi: 10.1152/ajpgi.00305.2010. Epub 2011 Mar 24.


In vivo monitoring of neuronal loss in traumatic brain injury: a microdialysis study.

Petzold A, Tisdall MM, Girbes AR, Martinian L, Thom M, Kitchen N, Smith M.

Brain. 2011 Feb;134(Pt 2):464-83. doi: 10.1093/brain/awq360.


Determinants of affinity and proteolytic stability in interactions of Kunitz family protease inhibitors with mesotrypsin.

Salameh MA, Soares AS, Navaneetham D, Sinha D, Walsh PN, Radisky ES.

J Biol Chem. 2010 Nov 19;285(47):36884-96. doi: 10.1074/jbc.M110.171348. Epub 2010 Sep 22.


The amyloid precursor protein/protease nexin 2 Kunitz inhibitor domain is a highly specific substrate of mesotrypsin.

Salameh MA, Robinson JL, Navaneetham D, Sinha D, Madden BJ, Walsh PN, Radisky ES.

J Biol Chem. 2010 Jan 15;285(3):1939-49. doi: 10.1074/jbc.M109.057216. Epub 2009 Nov 17.


High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer.

Gaber A, Johansson M, Stenman UH, Hotakainen K, Pontén F, Glimelius B, Bjartell A, Jirström K, Birgisson H.

Br J Cancer. 2009 May 19;100(10):1540-8. doi: 10.1038/sj.bjc.6605047. Epub 2009 Apr 21.


Genetic and biochemical characterization of the E32del polymorphism in human mesotrypsinogen.

Nemoda Z, Teich N, Hugenberg C, Sahin-Tóth M.

Pancreatology. 2005;5(2-3):273-8. Epub 2005 Apr 22.


Human mesotrypsin is a unique digestive protease specialized for the degradation of trypsin inhibitors.

Szmola R, Kukor Z, Sahin-Tóth M.

J Biol Chem. 2003 Dec 5;278(49):48580-9. Epub 2003 Sep 24.


Expression and characterization of trypsinogen produced in the human male genital tract.

Paju A, Bjartell A, Zhang WM, Nordling S, Borgström A, Hansson J, Stenman UH.

Am J Pathol. 2000 Dec;157(6):2011-21.


Expression of trypsin by epithelial cells of various tissues, leukocytes, and neurons in human and mouse.

Koshikawa N, Hasegawa S, Nagashima Y, Mitsuhashi K, Tsubota Y, Miyata S, Miyagi Y, Yasumitsu H, Miyazaki K.

Am J Pathol. 1998 Sep;153(3):937-44.


Isolation and characterization of the chicken trypsinogen gene family.

Wang K, Gan L, Lee I, Hood L.

Biochem J. 1995 Apr 15;307 ( Pt 2):471-9.

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